Degradable nanometer composite material for biological and medical use and method of preparation the same

Abstract

A nanometer-grade medical decomposable composite material and its preparation method. By different Ca / P, different crystallizing states in the inorganic phase, the composite material adjusts decomposing rate, recombines with decomposable polymer, thus the biological decomoposing rate of the whole composite material is adjustable. The inorganic phase is selected from one or two of amorphous calcium phosphate, alpha-tricalcium phosphate, beta-tricalcium phosphate, phosphorite and calcium phosphate dibasic. The preparation method comprises selecting organic solvents for uniformly dispersing calcium phosphate powder in a decomposable polymer matrix, then obtaining nanometer-grade composite material.

Description

technical field

[0001] The invention relates to a degradable biomedical nanocomposite material and a preparation method thereof, belonging to the technical field of preparation of biomedical substitute materials. Background technique

[0002] Due to diseases or trauma, hard tissues such as human bones or teeth are damaged or lost, and a large number of artificial synthetic substitute materials are needed for repair and treatment. At present, hard tissue replacement materials mainly include three types of materials: metals, ceramics, and polymers. They each have their own characteristics.

[0003] Metal materials have high strength and are easy to process. However, the price is expensive, and it does not match the bone stress, which will cause bone tissue resorption, and the metal ions produced by physiological corrosion will have adverse reactions to the tissue, and such materials need a second operation to remove after the tissue heals.

[0004] ...