135results about How to "The preparation process conditions are simple" patented technology

The invention discloses a macromolecular soluble microneedle used for polypeptide and protein medicines. The macromolecular soluble microneedle comprises a base as well as a needle body on the base and a needle point on the needle body, wherein the base and the needle body are made of a mixture of a high polymer material and a stabilizer; and solid active peptide or protein medicines are embedded into the needle point. The concentration degree of the medicines embedded in the needle point of the macromolecular soluble microneedle is relatively high, and nearly no residual medicines exist on the bottom of the needle body, so that the administration efficiency and the administration accuracy are greatly improved; in addition, the part entering the subcutaneous tissue of the needle body can rapidly dissolve, and further degrade to be completely absorbed by the tissues without toxic or side effects, so that the possible needle breaking risk existing in the microneedle made of other materials such as metal, glass and silicon is avoided. The preparation method of the macromolecular soluble microneedle is carried out under simple technological conditions, is low in price, and suitable for volume production, and the macromolecular soluble microneedle can be widely applied to the field of cutaneous penetration of macromolecular medicines.

The invention provides a multi-walled composite conductive carbon nanotube-polyvinylidene fluoride ultrafiltration membrane and a preparation method thereof. The multi-walled composite conductive carbon nanotube-polyvinylidene fluoride ultrafiltration membrane is prepared from polyvinylidene fluoride, N-N-dimethylacetamide and multi-walled carbon nanotubes. According to the conductive ultrafiltration membrane, the insulated polyvinylidene fluoride serves as a film-forming matrix, the carboxylated multi-walled carbon nanotubes serve as a nano conductive filler, the multi-walled carbon nanotubes are uniformly dispersed in the matrix by adopting an ultrasonic dispersion method, and the multi-walled composite conductive carbon nanotube-polyvinylidene fluoride ultrafiltration membrane is prepared by adopting a wet-phase inversion method. Because the carbon nanotubes have the extremely high conductivity, the conductive performance of the composite membrane is well improved due to the addition of the carbon nanotubes, and the strength and the hydrophilicity of the membrane are enhanced. Therefore, the membrane can be effectively prevented from being polluted during water treatment, and the service life of the membrane is prolonged. The preparation method and a process flow are simple, the operation is convenient, the cost is low, equipment is not required to be transformed, and the operability is high.

The invention discloses a thermosetting multi-component modified epoxy binder for using in the middle between IC cores and insulating underlay base boards and its preparation process, which belongs to the electronic device packaging technical field. The said binding agent is made of combined modified epoxide resin, latent curing agent, filler and addition auxiliary agent in a correct proportion, wherein the combined modified epoxide resin is made of bisphenol ethylene oxide resin as the main resin, alicyclic rings and naphthalene epoxide resin as the modified resin, the said latent curing agent is aromatic terminal group amine or alicyclic ring terminal group amine, the said filler is inorganic powder prepared by tensioactive treatment, the said addition auxiliary agent contains toning agent, accelerating agent, flame retardant and phenols curing agent. The said binding agent in the invention has many advantages such as high glass transition temperature, high adhesive property, high heat resistance, middle-and-low graded curing temperature and short curing time.

A nanometer-grade medical decomposable composite material and its preparation method. By different Ca/P, different crystallizing states in the inorganic phase, the composite material adjusts decomposing rate, recombines with decomposable polymer, thus the biological decomoposing rate of the whole composite material is adjustable. The inorganic phase is selected from one or two of amorphous calcium phosphate, ª‡- tricalcium phosphate, ª‰- tricalcium phosphate, phosphorite and calcium phosphate dibasic. The preparation method comprises selecting organic solvents for uniformly dispersing calciumphosphate powder in a decomposable polymer matrix, then obtaining nanometer-grade composite material.

The invention relates to a preparation method of a palladium-platinum bimetallic catalyst. The preparation method is characterized by using active carbon as a carrier, pretreating the active carbon respectively by hydrochloric acid and nitric acid before preparation, then simultaneously loading palladium and platinum on the pretreated active carbon, and adding an activating agent into the active carbon with palladium and platinum for reduction to finally obtain the palladium-platinum bimetallic catalyst. According to the invention, the preparation method is simple; and the obtained palladium-platinum bimetallic catalyst disclosed herein has the advantages of high activity, long life, etc, and is especially suitable for preparing o-phenylenediamine by solvent-free hydrogenation.

The present invention relates to a preparation method of fat-soluble tea polyphenol and aims to expand the use of the tea polyphenol by using the water-soluble tea polyphenol as raw material to prepare the fat-soluble tea polyphenol. In the preparation method, carbon acylation is used for preparing the fat-soluble tea polyphenol. More accurately, the preparation of the fat-soluble tea polyphenol causes no loss of phenolic hydroxyl of the raw material of tea polyphenol. Thus the product has improved fat-solubility and original antioxidant properties. The product can be dissolved in oil, fat and organic solvents but can not be dissolved in water. The antioxidant free group and anti-lipid overoxidation performance are similar to the tea polyphenol. The present invention also relates to a preparation method and conditions therefore for the esterification of class formation of catechin through carbon acylation. And the fat-soluble tea polyphenol has the performances that are superior to the products of the same class in the prior art.

The invention provides a geopolymer adsorption material and a preparation method thereof. The geopolymer adsorption material is prepared from the following raw materials in parts by weight: 15-35 parts of fly ash, 65-85 parts of metakaolin, 40-120 parts of water glass, 2-30 parts of sodium hydroxide and 30-90 parts of deionized water. The preparation method comprises the following steps that all the raw materials are uniformly mixed to obtain slurry, the slurry is injected into a mould to be alternately cured at a temperature of 80 DEG C and under a room temperature condition, and therefore, the geopolymer adsorption material is obtained. According to the geopolymer adsorption material and the preparation method thereof provided by the invention, the fly ash, the metakaolin and the like are taken as the raw materials to prepare the geopolymer adsorption material with high adsorption performance and low cost; on one hand, a new material is provided for removing heavy metal ions in sewage; on the other hand, the resource utilization of industrial waste can be realized, and the geopolymer adsorption material has a good application prospect.

The invention relates to successful preparation of a Co-MOF-71 nano-material. According to the invention, preparation process conditions are optimized; the prepared Co-MOF-71 nano-material is uniform in crystal grain size and has good stability; and when Co utilizes the acidic catalysis reaction of MOF framework metal ions, the metal ions are active sites and the supporting points of a framework, and metal ions undergo coordination in the process of catalysis. The prepared Co-MOF-71 material has high metal content and completely exposed metal sites; more Lewis acid site Co-MOF-71 materials can be provided; and the material is beneficial for total activation of reactant molecules and has good catalytic activity.

The invention provides a high-impedance material which is composed of the following components by weight percent: 10 to 30 % of bonding resin, 20 to 50 % of an opacifier, 30 to 65 % of a solvent and 0.03 to 0.2 % of an adhesive modifier. The high-impedance material provided by the invention can be used for preparing a black matrix (BM) which can play a role of isolation. By applying the black matrix to a liquid crystal display apparatus, induced charges generated due to electric field change at electrode lead areas on both sides of a lower substrate are enabled to gather and bound at the edge of an upper-side BM area at the instant of power on, and do not diffuse and leak into an inner side, so that situations of white lines on both sides of ADS products can be thoroughly resolved.

The invention discloses an oral insulin complexing preparation, which is characterized by the following: allocating 1-15% insulin raw material, 50-97% stable protecting agent, 1-15% carrying medicine carrier, 1-20% absorption promoting agent; setting the stable protecting agent as one or several of carbowax and casein, protamine, albumin and protease inhibitor; setting the carrying medicine carrier as calcium phosphate salt; setting the absorption promoting agent as one or several of salicylic acid, cholate and fatty acid; setting the insulin raw material as human retooling insulin or human retooling insulin chemical trimmed by single methoxy carbowax derivant. This invention also relates to a preparing method of oral insulin complexing preparation. This invention can increase biostability of human retooling insulin and can resist degradation of gastrointestinal tract enzyme.

The invention discloses a silica-based porous bulk for heat insulating material and a coating-dry pressing preparation method thereof. The preparation method comprises the following steps of: preparing porous silica powder through the hydrolytie polycondensation of tetraethoxysilane by using tetraethoxysilane as a precursor, a nonionic surfactant P123 as a template agent and trimethylbenzene as aswelling agent; hydro-thermally treating the silica powder so as to ensure that Si-OH in pore walls is completely polycondensed; coating the hydro-thermally treated silica powder with sol, and preparing the silica-based porous bulk for a heat insulating material by using the dry pressing method. The silica-based porous bulk is obtained by sintering the porous silica powder with oxide coated surface, wherein the oxide is alumina or titania. The mesoporous aperture of the silica-based porous bulk prepared by using the method is 21-35 nm, the mesoporous window is 10-18 nm, the total porosity is 65-82%, the mesoporosity is 80-99%, and the tensile strength is 45-180 MPa.

The invention discloses bone-like bio-medical material of a slow-release bioactive factor, the bone-like bio-medical material consists of a medical metal transplant body and the bone-like bioactive coating of the slow-release bioactive factor, and the bone-like bioactive coating is coated on the surface of the medical metal transplant body. The invention adopts an electrolytic deposition method to prepare, electrolyte solution contains calcium, a phosphorous compound, bone matrix collagen and the bioactive factor, the medical metal transplant body is taken as a working electrode, platinum is taken as a reference electrode, through the electrode reaction, the bone-like bioactive coating of the slow-release bioactive factor is deposited on the surface of the medical metal transplant body. Compared with the pure inorganic coating, through the adoption of the invention method, the bioactive coating acquired on the surface of the metal transplant body is similar to a natural bone in the component and the structure, and can control the slow-release bioactive factor, adjust, control and promote the growth of bones. The disadvantages that the biological activity of the business use hydroxyapatite coating is limited, the growth of bones cannot be promoted, the required curing time is long, etc. are solved. The preparation process of the invention is simple, highly effective and easy to be industrialized.

The invention discloses a phenylboronic acid hydrogel-based sugar-sensitive microneedle pad and a preparation method thereof. The phenylboronic acid hydrogel-based sugar-sensitive microneedle pad comprises a base and a microneedle array which is located on the base, wherein the base and microneedles are mainly prepared from a vinyl phenylboronic acid monomer and a vinyl monomer through free radical copolymerization; microneedle bodies and the base can both be used for embedding insulin drugs; the phenylboronic acid monomer is selected from 3-acrylamidophenylboronic acid, and the vinyl monomeris selected from N-isopropyl acrylamide and N-vinyl pyrrolidone. The preparation method disclosed by the invention is simple; the obtained phenylboronic acid hydrogel-based sugar-sensitive microneedlepad is regular in structure, has good mechanical performance, is capable of effectively piercing the skin, has stimulus responsiveness to glucose concentration, and is capable of regulating the release rate and the dosage of insulin according to blood sugar concentrations and effectively preventing a risk of hypoglycemia caused by excessive release of the insulin.

The invention relates to a preparation method of a modified magnesium borate whisker/PP (propene polymer) composite material. In the method, a PP material is used as a matrix, and a borate coupling agent modified magnesium borate whisker is used as reinforcement. The preparation method comprises the following steps of: (1) sufficiently dissolving 1 to 3 parts by mass of borate coupling agent with a proper amount of absolute ethanol at a temperature of between 30 and 50 DEG C, and uniformly mixing for 0.5 to 1 hour with 97 to 99 parts by mass of magnesium borate whisker which is dried for 4 hours at a temperature of between 120 and 140 DEG C, filtering, cleaning, and baking at a temperature of between 90 and 120 DEG C for 4 to 6 hours to obtain a surface modified whisker; (2) preheating a mixing mill to a temperature of between 180 and 200 DEG C, adding a PP base material to melt for 3 to 5 minutes, and adding the borate coupling agent modified magnesium borate whisker which is prepared in the step (1) according to a proportion to mix for 8 to 10 minutes to prepare a semifinished product; and (3) molding the semifinished product prepared in the step (2) for 6 to 8 minutes in a molding machine at a pressure of 10MPa and a temperature of between 180 and 185 DEG C to prepare the modified magnesium borate whisker/PP composite material. The preparation method of the invention has the advantages of simple conditions and low cost; and the mechanical performance of the modified magnesium borate whisker/PP composite material is remarkably improved, and the application prospect is wide.

The invention relates to an indium doped zinc oxide transparent conducting film and a preparation method thereof. In the method, a ZnO:In transparent conducting film with a polycrystal structure is prepared on a common alkali glass and quartz glass substrate by adopting a multitarget co-sputtering magnetron sputtering technology and adopting a zinc oxide ceramic target and indium metal target co-sputtering method. In the process condition, the pressure of the argon and oxygen mixed working gas is 0.2-2.0Pa; the volume ratio of the oxygen to the argon is 0-0.2; the sputtering power of a zinc oxide target and an indium target are respectively 50-200W and 5-40W; the substrate temperature is room temperature-500 DEG C; and the bias voltage is 0-negative 200V. The prepared transparent conducting film reduces indium atomic number content to 2 percent, has favorable conducting performance, transmissivity larger than 90 percent at 400-1,100nm and can be widely applied to the fields of solar batteries, panel display, and the like instead of ITO (Indium Tin Oxide).

The invention relates to a water-coating-sand colorful paint and a preparation method thereof. The paint includes, by weight, 15-20 parts of a resin compound emulsion, 30-45 parts of compound powder, 3-5 parts of an additive, 30-50 parts of color sands, and 20-30 parts of water, wherein the resin compound emulsion is prepared by mixing acrylic pure acrylic emulsion and silicone acrylic emulsion. The additive includes, by weight, 0.3-0.5 parts of dodecanoate, 0.8-1.2 parts of propylene glycol, 0.2-0.4 parts of a wetting agent X-405, 0.2-0.4 parts AMP-95 neutralizing amine, 0.5-0.8 parts of an ammonium salt dispersant, 0.2-0.4 parts of a defoamer, 0.7-1 part of a DR-72 alkali swelling thickener, 1-1.2 parts of aluminum-magnesium silicate, 0.3-0.5 parts of cellulose, and 0.5-1 part of a liquid stabilizer. Compared with the prior art, the paint has good water resistance, extensibility and stain resistance, is low in preparation cost, is good in storage stability, is easy to construct and saves labor hour.

The invention discloses a preparation method for superparamagnetism ferrite nano particles, relates to nanometer materials and provides a quick, environment-friendly and convenient preparation method for the superparamagnetism ferrite nano particles. The preparation method comprises the following steps: adding a sodium hydroxide solution into oleinic acid, stirring so as to obtain a white sodium oleate solid; then utilizing absolute ethyl alcohol to dissolute the sodium oleate solid during the stirring process and obtaining a homogeneous and transparent solution A; adding a hydrazine hydrate solution into the solution A during the stirring process; continuously stirring, enabling reactants to be well mixed and obtaining a homogeneous and transparent solution B; sequentially adding a Fe <3+> salt solution and a M<2+> salt solution into the solution B, stirring, enabling reactants to be well mixed and obtaining a solution C; transferring the solution C to a quartz reaction tube of a microwave synthesizer; sealing the solution C, packing the solution C into the microwave synthesizer and conducting a microwave synthesis; when the reaction stops, taking out the reaction vessel and adding the absolute ethyl alcohol; conducting an ultrasonic washing or centrifugal separation on the products; obtaining the superparamagnetism ferrite nano particles after the drying.