Application of ligusticum oil in preparation of medicine for treating cerebral thrombosis

A technology of Chuanxiong oil and cerebral thrombosis, which is applied in the application field of preparing medicines for treating cerebral thrombosis, can solve problems that have not been reported before, and achieve the effects of strong drug effect, good medicinal prospects, and high export profits

Inactive Publication Date: 2006-12-27
SICHUAN HEZHENG PHARM CO LTD
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the use of Chuanxiong oil in the preparation of medicines for the treatment of cerebral thrombosis has never been reported.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Embodiment 1: Chuanxiong oil soft capsule

[0032] Efficacy of the new drug: analgesia, sedation, reduction of vascular resistance, increase of cerebral blood flow, anti-thrombosis.

[0033] Indications: Treatment of vascular nerve headache, cerebral thrombosis, and cerebrovascular sclerosis.

[0034] Applicable amount: 300-1500 mg

[0035] Made with a single flavor. Ligusticum chuanxiong medicinal materials were dried, pulverized, passed through an 8-mesh sieve, and washed with supercritical CO 2 Extraction, extraction temperature 46°C, extraction pressure 25Mpa, CO 2 The flow rate is calculated as 20Kg / hr per kilogram of crude drug of Chuanxiong Rhizoma Chuanxiong. After extracting in the separation tank for 100 minutes, the collected extracts are combined, placed in a volatile oil separator, and left to stand at room temperature for 5 hours, and the oil layer is centrifuged (3000 rpm). Put the obtained Chuanxiong oil in a brown bottle and seal it for storage; amo...

Embodiment 2

[0037] Embodiment 2: Chuanxiong oil tablet

[0038] Made with compound. choose supercritical CO 2 The extracted chuanxiong oil and angelica oil are prepared according to the ratio of 1:0.1-20.

[0039] The present invention can also choose supercritical CO 2 The extracted chuanxiong oil and angelica oil are made into medicine according to the ratio of 1:0.1-30 or borneol according to the ratio of 1:1-500.

[0040] The present invention has exerted new medical application to the Chinese medicine Rhizoma Chuanxiong, has opened up a new application field, adopts supercritical CO 2 The extracted Chuanxiong oil is safe and non-toxic, has strong medicinal effects, and has a good medicinal prospect, and Chuanxiong has abundant raw materials, low price, simple extraction process, low cost of making traditional Chinese medicine, high export profit, and can be made into various dosage forms .

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

An application of Chuan-xiong oil extracted from Chuan-xiong rhizome by supercritical Co2 in preparing the medicine for treating cerebral thrombus is disclosed.

Description

Technical field: [0001] The present invention relates to the purposes of Chuanxiong oil, especially relate to the use of supercritical CO 2 Application of extracted Chuanxiong oil in preparation of medicine for treating cerebral thrombosis. Background technique: [0002] Cerebral thrombosis, also known as arteriosclerotic cerebral infarction, refers to the formation of thrombus on the basis of cerebral artery intimal lesions, resulting in stenosis or occlusion of the vessel lumen, obstruction of blood flow, resulting in acute cerebral blood supply insufficiency and local brain tissue necrosis. [0003] The common cause of this disease is that cerebral atherosclerosis, hypertension, hyperlipidemia, and diabetes can often promote the development of arteriosclerosis. Other causes include various cerebral arteritis, moyamoya disease, connective tissue disease, polycythemia vera, hypercoagulable state, etc. Atherosclerosis is most likely to occur at the bifurcations and bends o...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/236A61K9/02A61K9/16A61K9/08A61K9/10A61K9/20A61K9/48A61P7/02A61P9/10A61K125/00
Inventor 刘传捷胡坦莲张廷模
Owner SICHUAN HEZHENG PHARM CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap