Dripping pills for treating high blood fat and its preparing method

A technology of Xiangdropping pills and rhubarb, applied in the field of Huangxiang dropping pills and its preparation, can solve the problems of low dissolution rate, inaccurate dosage, large dosage, etc., achieve faster dissolution and absorption, improve bioavailability, and take The effect of small doses

Inactive Publication Date: 2007-01-31
北京博智绿洲医药科技有限公司
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  • Application Information

AI Technical Summary

Problems solved by technology

[0012] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect
However, the granule preparation also has the disadvantages of low drug content, large dosage, inaccurate dosage, inconvenient taking, and inconvenient carrying.
[0013] In addition, conventional oral dosage forms, such as tablets, capsules, etc., will produce relatively large dust pollution due to the granulation process in the preparation process, which will cause harm to the health of the staff to a certain extent, and will also give some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0038] Now with several groups of specific examples, the preparation method of Huangxiang dripping pills of the present invention will be further described.

[0039] Group 1: Tests with a single matrix

[0040] 1. Weigh a certain amount of traditional Chinese medicine raw materials according to the ratio given in [Preparation Method] 1, and then prepare two pure Chinese medicine active ingredients containing rhubarb and patchouli according to the section [Appendix: a preparation method of a Chinese medicine extract] Extract dry powder and volatile oil for standby;

[0041] 2. Substrate: polyethylene glycol (2000、4000、6000、8000、10000、20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc. pharmaceutical carrier;

[0042] 3. Proportion—in g or kg, in parts by weight, drug extract: matrix = 1:1~1:9;

[0043] 4. Then prepare according to the process of [Prepa...

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PUM

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Abstract

The invention relates to a medicinal oral preparation with the functions of promoting blood flow, antihyperglycemic and treating hyperlipoidemia, which has the advantages of high biological availability, quick-speed medicine release, quick-speed effect, less toxic and side effects, higher medicinal content, smaller amount of administration, accurate administration dosage, easy administering, low price, and facilitated carrying. The medicine is prepared through the conventional drop pill preparing process.

Description

technical field [0001] The invention relates to a pharmaceutical composition which has the effect of promoting blood circulation, removing turbidity and lowering lipids, and is used for treating hyperlipidemia caused by stasis and dampness, in particular to a Chinese medicine Chenghuangxiang granule, which is formulated through dosage form. The pharmaceutical composition is an oral drop pill preparation. Background technique [0002] According to the formula and extraction process given in the national drug standard WS-10902 (ZD-0902)-2002, Huangxiang granule is a kind of granule that has the effect of promoting blood circulation, removing turbidity and lowering fat, and is used for the treatment of turbidity caused by dampness. The oral pure Chinese medicine preparation for hyperlipidemia has been clinically verified, has stable quality and definite curative effect, and is a commonly used pharmaceutical preparation for clinical and family treatment of the above diseases. ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/20A61K36/708A61K36/53A61P3/06
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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