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'Wudan Xinggan' granular for treating fatty liver, and its prepn. method

A technology for fatty liver and granules, which is applied in the field of Wudan Xinggan Granules and its preparation, which can solve the problems of complex preparation methods, many drug prescriptions, and large active ingredients, and achieve simple preparation processes, small loss of active ingredients, and toxic and side effects small effect

Inactive Publication Date: 2007-05-02
吉林修正药业新药开发有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But its medicine prescription is more, and preparation method is complicated, and active ingredient is big, has certain toxic and side effects

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] a: Take 600g of Salvia miltiorrhiza and add 6000mL, 4800mL of 80% ethanol to heat and reflux twice for 2 hours and 1 hour, combine the extracts, filter and concentrate to about 180g of clear paste with a relative density of 1.20-1.22 (60-75°C) ,spare:

[0026] b: Add 4800 mL and 3600 mL of water to the medicinal residues, decoct for 2 hours and 1 hour, combine the filtrates, concentrate to about 210 g of clear paste with a relative density of 1.20-1.22 (60-75°C), and set aside;

[0027] c: Take 450g of Radix Polygoni Multiflori, 25g of Hawthorn, add 7000mL, 5600mL of 60% ethanol and heat and reflux twice for 1.5 hours and 1 hour, combine the extracts, filter, and concentrate to a relative density of 1.20-1.22 (60-75°C) about 72g of clear paste, set aside;

[0028] d: Combine the above clear pastes, add appropriate amount of dextrin and 5 g of stevioside to make 100 g of granules, and pack them.

[0029] Usage and Dosage: Take it orally, three times a day, 6g each time...

Embodiment 2

[0031] a: 700g of Salvia miltiorrhiza plus 7000mL, 5600mL of 80% ethanol and heated and refluxed twice for 2 hours and 1 hour, combined the extracts, filtered, and concentrated to about 210g of clear paste with a relative density of 1.20-1.22 (60-75°C), spare;

[0032] b: Add 5600mL and 4200mL of water to the dregs, decoct for 2 hours and 1 hour, combine the filtrate, concentrate to about 245g of clear paste with a relative density of 1.20-1.22 (60-75°C), and set aside;

[0033] c: Prepare Radix Polygoni Multiflori 550g, Hawthorn 350g, add 9000ml, 720mL 60% ethanol to heat and reflux twice for 1.5 hours and 1 hour, combine the extracts, filter and concentrate to a relative density of 1.20-1.22 (60-75°C) About 230g of clear paste, set aside;

[0034] d: Combine the above clear pastes, add appropriate amount of dextrin and 5 g of stevioside to make 1000 g of granules, and pack them.

[0035] Usage and Dosage: Take it orally, three times a day, 6g each time.

Embodiment 3

[0037] a: 666.7g of Salvia miltiorrhiza plus 6667mL, 5333mL of 80% ethanol and heated and refluxed twice for 2 hours and 1 hour, combined the extracts, filtered, and concentrated to about 200g of a clear paste with a relative density of 1.20-1.22 (60-75°C) ,spare;

[0038] b: Add 5333 mL and 4000 mL of water to the dregs, decoct for 2 hours and 1 hour, combine the filtrate, concentrate to about 233 g of clear paste with a relative density of 1.20-1.22 (60-75°C), and set aside;

[0039] c: Prepare Shouwu 500g, hawthorn 333.3g, add 8333mL, 6666mL 60% ethanol to heat and reflux for two times for 1.5 hours and 1 hour, combine the extracts, filter, and concentrate to a relative density of 1.20-1.22 (60-75°C) about 225g of clear paste, set aside;

[0040] d: Combine the above clear pastes, add appropriate amount of dextrin and 5 g of stevioside to make 1000 g of granules, and pack them.

[0041] Usage and Dosage: Take it orally, three times a day, 6g each time.

[0042] The above...

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Abstract

A Chinese medicine in the form of particles for treating fatty liver is prepared from red sage root, fleece flower root and haw through respectively extracting active components, mixing, adding dextrin and rebaudiose, and granulating.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation for treating fatty liver and a preparation method thereof, in particular to Wudan Xinggan Granules for treating hyperlipidemia fatty liver or alcoholic fatty liver disease and a preparation method thereof. Background technique: [0002] With the improvement of people's living standards, the incidence of hyperlipidemia fatty liver or alcoholic fatty liver disease is increasing. At present, there is no ideal specific drug for the treatment of fatty liver at home and abroad. Gynostemma Gynostemma, Duoxikang, Clofibrate, Lepingzhi, etc. are commonly used in clinical practice. Most of them have moderate effects and no significant curative effect. Some drugs can damage the liver after long-term use, so they are not suitable for the treatment of fatty liver. toxic side effect. [0003] Chinese patent CN1343514, a traditional Chinese medicine compound preparation for treating fatty liver. Th...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/734A61K36/704A61K36/53A61K9/16A61P1/16A61P3/06
Inventor 张惠云
Owner 吉林修正药业新药开发有限公司