Method for preparing ginkgo leaf extractive

An extract and technology of ginkgo biloba, which is applied in the field of preparation of ginkgo biloba extract, can solve the problem of unstable content, difficulty in producing high-quality ginkgo Ester ratio and other issues, to achieve the effect of simple process, low production cost and stable quality

Inactive Publication Date: 2004-02-04
山西振东泰盛制药有限公司
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Benefits of technology

This patented technology allows for efficient creation of pure or enriched gingerbanks without affecting their taste qualities like other plants such as Glycyrrhiza glabra (Gaura cathayensis). It also ensures consistently good yields from these sources due to its unique composition containing more than 24 different compounds called gallocinins A/B and 3 carboxylic acids.

Problems solved by technology

This patented technical problem addressed in this patents relates to improving the production process or purity level of gallium bicobalte (Gb) extracted through water extractions with different types of solvent systems like ethyl alcohol/water system, acetone solution, but due to changes over time caused by environmental conditions during manufacturing, these components may change their concentration within certain limits leading to decreased effectiveness of the final product's ability to deliver medications safely into blood vessels.

Method used

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  • Method for preparing ginkgo leaf extractive
  • Method for preparing ginkgo leaf extractive

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Embodiment Construction

[0021] specific implementation plan

[0022] The processing steps of preparing ginkgo extract are as follows:

[0023] (1) Extract the active ingredients of Ginkgo biloba,

[0024] (1.1), after the dried ginkgo leaves are pulverized, put them in a water bath, add respectively 5 times, 4 times, and 3 times of ethanol of the weight of the dried ginkgo leaves to extract the ginkgo leaves for 3 hours, 2 hours, and 1 hour respectively. hour, the extraction temperature is 70°C, and the ethanol concentration is 75%. After each extraction, the extract is collected, and the extracts collected three times are combined;

[0025] (1.2), the resulting extract is filtered and concentrated into a concentrated solution in vacuum;

[0026] (1.3), the concentrated solution of gained is added acidic ethanol solution, and this acidic solution is the ethanol solution that concentration is 15% ethanol is adjusted to pH value 3 with hydrochloric acid, let stand for 10 hours, make it fully precipit...

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Abstract

A process for preparing the extract of ginkgo leaf includes such steps as pulverizing ginkgo leaves, immersing in alcohol, concentrating, depositing in wine, refining ginkgo flavone from supernatant by macroreticular resin method, refining ginkgo lactone from deposit by supercritical CO2 method, and proportionally mixing them together. Its advantages are low cost, high purity and stability, and high output rate (more than 80%).

Description

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Claims

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Application Information

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Owner 山西振东泰盛制药有限公司
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