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Almond cough-relieving drop pills and preparation method thereof

A technology for almonds and dropping pills, applied in the field of pharmaceutical compositions, can solve the problems of low dissolution rate, unfavorable improvement of patients' ability to seek medical treatment, increase in medication cost, etc., and achieves accelerated dissolution and absorption, improved bioavailability, and increased total surface area. Effect

Inactive Publication Date: 2005-07-06
北京博智绿洲医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect
In addition, conventional oral dosage forms, such as tablets, capsules, granules, etc., will produce relatively large dust pollution due to the granulation process in the preparation process, which will cause harm to the health of the staff to a certain extent, and also Will cause some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0030] The preparation method of Xingren Zhike Dropping Pills of the present invention will be further described with several groups of specific examples.

[0031] Group 1: Tests with a single matrix

[0032] 1. Take l or ml as the unit, using commercially available finished products, almond water 30.2%, polygala fluid extract 17%, tangerine peel fluid extract 11.3%, bellflower fluid extract 15.1%, licorice fluid extract 11.3%, babuliu Extraction 15.1%; the above six flavors, the almond water is mixed with each liquid extract, concentrated to a thick paste with a relative density of 1.30 or more, and then dried at low temperature and crushed to obtain a dry powder for subsequent use;

[0033] 2. Substrate: polyethylene glycol (2000、4000、6000、8000、10000、20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc. pharmaceutical carrier;

[0034] 3. Proportion: t...

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PUM

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Abstract

The invention discloses an apricot kernel cough-relieving drop pills, which is a medicinal oral preparation having the functions of cough-relieving and phlegm reducing, and can be used for treating acute and chronic bronchitis, cough and expectoration. The drop pill has the advantages of high biological availability, quick-speed medicine release, quick-speed effect, less toxic and side effects, higher medicinal content, smaller amount of administration, accurate administration dosage, easy administering, low price, and facilitated carrying. The drop pill is prepared through the conventional apricot kernel cough-relieving electuary preparing processes.

Description

technical field [0001] The present invention relates to a kind of pharmaceutical composition which has the function of reducing phlegm and relieving cough, and is used for treating acute and chronic bronchitis, cough with phlegm and other symptoms, especially relates to a traditional Chinese medicine Xingren Zhike Granules, which is formulated through formulation reformation. The pharmaceutical composition is an oral drop pill preparation. Background technique [0002] According to the ministerial drug standard WS 3 - Xingren Zhike Granule prepared according to the formula and extraction process given in B-0552-91 is a pure oral syrup that has the effect of resolving phlegm and relieving cough, and is used to treat symptoms such as acute and chronic bronchitis, cough and phlegm. Traditional Chinese medicine preparations have been clinically verified to have stable quality and definite curative effect, and are commonly used in clinics and households. [0003] The following ...

Claims

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Application Information

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IPC IPC(8): A61K9/20A61P11/10A61P11/14
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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