Musk precordial pain relieving drop pills and preparation method thereof
A technology of musk and dripping pills, applied in the directions of pill delivery, pharmaceutical formulations, cardiovascular system diseases, etc., can solve the problems of long dissolution time, low bioavailability, unfavorable for critically ill patients and allergic patients, etc., to avoid gastrointestinal tract. Irritant symptoms, accelerated dissolution and absorption, improved bioavailability
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Publication Date
- 2005-07-06
- Estimated Expiration
- Not applicable · inactive patent
Abstract
Description
technical field
[0001] The present invention relates to a kind of medicinal composition which has the effects of aromatic resuscitation, regulating qi and relieving pain, and is used for treating chest obstruction and heartache caused by qi stagnation and blood stasis, such as chest obstruction, chest pain, suffocation and other symptoms. Basic, a kind of pharmaceutical composition oral drop pill preparation that forms through dosage form reformation. Background technique
[0002] According to the formula and preparation process given in the national drug standard WS-10579 (ZD-0579)-2002, Musk Heart Pain Ointment is prepared, which has the functions of aromatic resuscitation, regulating qi and relieving pain, and is used to treat diseases caused by stagnation of qi and blood stasis. Chest obstruction and heart pain, oral Chinese medicine preparations for symptoms such as chest obstruction, chest pain, and suffocation, have been clinically verified to have stable quality and ...
Examples
Embodiment Construction
[0042] Now with several groups of specific examples, the preparation method of the Shexiang Xintong dripping pills of the present invention will be further described.
[0043] Group 1: Tests with a single matrix
[0044]1. Weigh a certain amount of drug raw materials according to the ratio given in [Preparation Method] 1, and then follow [Appendix 1: A preparation method for medicinal thick paste or dry powder], [Appendix 2: Preparation of Angelica dahurica liquid extract] and [Appendix 3: Preparation of Pig Tooth Soap Extract] The given method firstly prepares the active ingredients of the medicine containing musk, angelica liquid extract, pig tooth soap liquid extract, borneol, methyl salicylate, camphor, and diphenhydramine hydrochloride dry powder for use;
[0045] 2. Substrate: polyethylene glycol (2000、4000、6000、8000、10000、20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glyc...