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Production of containing bupleurum root, seed of spine date and soybean isoflavone for improving sleeping, preparation method and application

A soy isoflavone and sleep-improving technology, which can be used in medical preparations containing active ingredients, pharmaceutical formulations, nervous system diseases, etc., can solve problems such as large side effects of hormones, achieve no toxic side effects, wide adaptability, and improve sleep state. Effect

Inactive Publication Date: 2005-08-31
江西中天医药生物有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In western countries, menopausal women generally use estrogen replacement therapy, but the current situation is that hormone side effects are relatively large

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] No. 1 product formula (parts by weight): 125 parts of Bupleurum bupleurum, 250 parts of wild jujube seed, and 10 parts of soybean isoflavone.

[0029] Production process: Weigh Bupleurum and Suanzaoren according to the ratio of ingredients in the formula, add 10 times the amount of water to decoct, decoct for 2 hours for the first time, add 8 times the amount of water for 1 hour for the second time; combine the two filtrates, decompress Concentrate into an extract with a measured relative density of 1.08 at 45°C, spray dry to obtain a dry powder; mix the dry powder with soybean isoflavones and add 30% ethanol solution to boil and granulate; after the granules pass the inspection, fill them with No. 2 hollow capsules; remove powder, Polished; packaged to be a finished product.

[0030] The product prepared by the above-mentioned method is 0.25g per capsule, the water content should not be higher than 8.0%, and the total flavonoids should not be lower than 80mg / g.

[003...

Embodiment 2

[0043] No. 2 product formula (parts by weight): 200 parts of Bupleuri, 200 parts of Suanzaoren, 125 parts of Poria cocos, 125 parts of Radix Paeoniae Alba, 125 parts of Angelica sinensis, 125 parts of Gardenia, 25 parts of licorice, 10 parts of soybean isoflavones.

[0044] Production Process:

[0045] Ingredients of Bupleurum, Suanzaoren, Poria, Paeoniae Alba, Angelica, Gardenia, Licorice and other seven medicinal materials are prepared according to the formula; add 10 times the amount of water and decoct twice, the first time for 2 hours, the second time for 1 hour; combine the two The filtrate is concentrated under reduced pressure into an extract with a relative density of 1.06 to 1.10 measured at 40°C to 50°C, and spray-dried to obtain a dry powder; the dry powder is mixed with soybean isoflavones and then added with 30% ethanol solution to boil and granulate; after passing the particle inspection , filled with No. 1 hollow capsules; depowdered and polished; packaged to o...

Embodiment 3

[0053] No. 3 product formula (parts by weight):

[0054] 125 parts of Bupleurum, 250 parts of Suanzaoren, 125 parts of Poria cocos, 125 parts of white peony, 125 parts of angelica, 125 parts of gardenia, 125 parts of licorice, 75 parts of pearl, and 10 parts of soybean isoflavones.

[0055] Production Process:

[0056] Ingredients of Bupleurum, Suanzaoren, Poria, Paeoniae Alba, Angelica, Gardenia, Licorice and other seven medicinal materials are prepared according to the formula; add 10 times the amount of water and decoct twice, the first time for 2 hours, the second time for 1 hour; combine the two The filtrate is concentrated under reduced pressure into an extract with a relative density of 1.06 to 1.10 measured at 40°C to 50°C, and spray-dried to obtain a dry powder; the dry powder is mixed with pearl powder and soybean isoflavones, and then added with 30% ethanol solution to boil and granulate; After passing the inspection, fill with No. 1 hollow capsules; remove powder ...

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PUM

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Abstract

A health-care and medical product for treating insomnia and improving quality of sleeping is prepared from bupleurom root, wild jujube kernel and soybean isoflavone. Its preparing process is also disclosed.

Description

technical field [0001] The invention relates to a new product with therapeutic and health care functions, especially a product made of Bupleurum chinensis, wild jujube seed, soybean isoflavone, etc., which can regulate mood and improve sleep. Background technique [0002] Insomnia, also known as sleep disorder, is a condition of unsatisfactory quality and / or quantity of sleep that lasts for a considerable period of time, often manifested as difficulty falling asleep, falling asleep, maintaining sleep, and waking up prematurely or intermittently. cause sleep deprivation. Insomnia is one of the most common sleep disorders, almost everyone has experienced insomnia. With the development of society and the quickening pace of life, the incidence of insomnia has an upward trend. According to statistics, about 30% of adults suffer from insomnia, and it becomes more prominent with the increase of age, and insomnia symptoms can be as high as more than 70% among the elderly. The mai...

Claims

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Application Information

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IPC IPC(8): A61P25/20
Inventor 龚建平杨世林饶毅曾燕斌钟文军游剑
Owner 江西中天医药生物有限公司
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