Hemostatic beautyberry dripping pill and its preparing method

A technology of purple beads and dropping pills, applied in the directions of pill delivery, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve problems such as adverse overall health level, low dissolution rate, inconvenient taking or carrying, etc. Labor protection and environmental protection, the effect of accelerating dissolution and absorption, and improving bioavailability

Inactive Publication Date: 2005-10-19
北京博智绿洲医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect
However, syrup oral preparations also have disadvantages such as low drug content, difficulty in taking and measuring accurately, inconvenient taking or carrying, etc.
[0007] In addition, conventional oral dosage forms, such as tablets, capsules, etc., will produce relatively large dust pollution due to the granulation process in the preparation process, which will cause harm to the health of the staff to a certain extent, and will also cause harm to the human body. some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0028] Several sets of specific examples are now used to further illustrate the preparation method of the dripping pill formulation of the present invention.

[0029] The first group: single matrix test

[0030] 1. Raw materials: dry powder of extracts containing the effective ingredients of the traditional Chinese medicine Porphyratum leaves prepared according to the preparation method 1;

[0031] 2. Matrix: polyethylene glycol (1000、2000、4000、6000、8000、10000、20000) , Polyoxy 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc.;

[0032] 3. Proportion: in g or kg, in parts by weight, drug extract: matrix = 1:1 to 1:9;

[0033] 4. According to the process given in [Preparation Method] 4~7, you can get Zizhu Hemostatic Dropping Pills of different specifications.

[0034] [test results]

[0035] Test 1: In order to observe the difference in the quality of the Zizhu Zhixue Droppin...

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PUM

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Abstract

The present invention relates to a kind of medicine composition, hemostatic beautyberry dripping pill, with functions of clearing away heat and toxic material and astringing to arrest bleeding and for treating gastrointestinal bleeding, hematochezia, traumatic breeding, etc. The present invention has high bioavailability, fast medicine release, fast acting, high effective content, taking convenience and low cost. The manyprickle acanthopanax -ginseng -astragalus dripping pill is prepared with Chinese medicinal material beautyberry leaf and medicine carrier as matrix.

Description

Technical field [0001] The invention relates to a pharmaceutical composition with the effects of clearing away heat, detoxifying, astringent and hemostasis, and is used for the treatment of gastrointestinal bleeding, hematochezia, hemoptysis, traumatic bleeding and other diseases, and particularly relates to a pharmaceutical composition prepared from the traditional Chinese medicine Echinacea leaves as raw materials The pharmaceutical composition is an oral preparation. Background technique [0002] According to the Ministry of Drug Standard WS 3 -The Zizhu hemostatic oral liquid prepared by the preparation method given in B-2435-97 is a kind of clearing away heat, detoxifying, astringent and hemostasis effect, used for the treatment of gastrointestinal bleeding, blood in the stool, hemoptysis and traumatic bleeding. Oral syrup preparations. This product has been clinically verified and has definite curative effect. It is a common medicine used clinically and at home to treat the...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/20A61P1/00
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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