Kaihoujian drip pill for treating throat disease and its preparation method

A technology of Kaihoujian and dripping pills, which is applied in the field of Kaihoujian dripping pills for treating throat diseases and its preparation, can solve the problems of low dissolution rate, high cost of spray manufacturing, unfavorable overall health level, etc., and achieve dissolution Accelerate absorption, improve bioavailability, and benefit labor protection

Inactive Publication Date: 2005-10-26
北京博智绿洲医药科技有限公司
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AI Technical Summary

Problems solved by technology

[0007] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect
Sprays are expensive to manufacture and inconvenient to use. At the same time, they can only be used as external medication and cannot treat both symptoms and root causes.
[0008] In addition, conventional oral dosage f

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0029] Several specific examples are now used to further illustrate the preparation method of the Kaihoujian dripping pill of the present invention.

[0030] The first group: single matrix test

[0031] 1. Raw materials: According to the [Appendix], prepare dry powder extracts containing four active ingredients of traditional Chinese medicine, such as Golden Dragon, Shandougen, Cicada, Menthol, etc.;

[0032] 2. Matrix: polyethylene glycol 1000 Polyethylene glycol 4000 Polyethylene glycol 6000 Polyethylene glycol 10000 Polyethylene glycol 20000 , Span 40, Polyoxy 40 stearate, poloxamer, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac;

[0033] 3. Proportion: in g or kg, in parts by weight, drug extract: matrix = 1:1 to 1:9;

[0034] 4. According to the process given in [Preparation Method] 4-7, Kaihoujian dripping pills of different specifications can be obtained.

[0035] [test results]

[0036] Test 1: In order to observe the difference in the qua...

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Abstract

A Chinese medicine in the form of dripping pill for treating pharyngolaryngitis, tonsillitis, sore throat, stomatitis, gingivitis, etc is prepared from 4 Chinese-medicinal materials including subprostrate sophora root, ciccada slough, menthol, etc. Its preparing process is also disclosed.

Description

Technical field [0001] The invention relates to a pharmaceutical composition that has the effects of clearing away heat, detoxifying, reducing swelling and relieving pain, and is used for the treatment of acute and chronic pharyngitis, tonsillitis, sore throat, stomatitis, gum swelling and pain, etc. A medicinal composition oral preparation prepared from the active ingredient extracts of four traditional Chinese medicines, such as shandougen, cicada slug, and menthol. Background technique [0002] According to the preparation method given in the national drug standard WS-10132(ZD-0132)-2002, the Kaihoujian spray is a kind of heat-clearing, detoxifying, swelling and pain-relieving effects. It is used for acute and chronic pharyngitis. Oral granules for the treatment of tonsillitis, sore throat, stomatitis, gingival swelling and pain, etc., have been clinically verified and have a definite effect. They are commonly used clinically and at home to treat the above-mentioned diseases. ...

Claims

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Application Information

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IPC IPC(8): A61K35/64
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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