Zuanshanfeng guttage pill and preparing method

A technology of drilling mountain winds and dripping pills, which is applied in the fields of pill delivery, pharmaceutical formulations, and medical preparations containing active ingredients, etc. It can solve the problems of immature preparation of dripping pills, affecting the accuracy of dosage, and increasing the cost of medication for patients, etc. problems, to achieve the effect of improving bioavailability, drug safety, and low production cost

Inactive Publication Date: 2006-03-08
北京博智绿洲医药科技有限公司
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AI Technical Summary

Problems solved by technology

[0009] Yet, because the preparation technology of drop pill is not yet very mature, and its related equipment has not yet reached the degree of standardization, when utilizing existing technology to prepare drop pill, product quality is affected by the physicochemical property of medicine, the kind of matrix and its mixing with medicine. Influenced by factors such as ratio, condensing agent and its temperature, indicators such as rounding rate and pill weight difference are quite different from the quality indicators of dripping pill preparations stipulated in the national drug standards. Such products seriously affect the dosage in use. The accuracy of the product also reduces the qualified rate of the product in production, increases the production cost, and indirectly increases the drug cost of the patient, thus reducing its practicability

Method used

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Examples

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Embodiment Construction

[0031] Now with several groups of specific examples, the preparation method of Zhuanshanfeng dripping pills of the present invention will be further described.

[0032] [recipe selection]

[0033] 1. Raw materials: According to the [Appendix], the extracts containing the active ingredients of 7 traditional Chinese medicines, such as Zhuanshanfeng, Gouercha, Sikuaiwa, Clematis, Qianjinba, Fengcheng Spatholobus, and Ginger, are prepared in advance for use ;

[0034] 2. Single matrix: selected from polyethylene glycol 1000 , polyethylene glycol 4000 , polyethylene glycol 6000 , polyethylene glycol 10000 , polyethylene glycol 20000 , Span 40, polyoxyl 40 stearate, poloxamer, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac and other carriers;

[0035] 3. Combination matrix: take g or kg as the unit, by weight, choose polyethylene glycol, polyoxyl 40 stearate, sodium carboxymethyl starch, beta cyclodextrin, Tween and other carriers for combinati...

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Abstract

The Chinese medicine composite zuanshanfeng dripping pills preparation for curing the diseases of cold pain in the lumbus and knees, numbness of the limbs and inhibited bending and stretching resulted from arthralgia due to wind-cold-dampress is made up by using extract of 7 Chinese medicinal materials of zuanshanfeng. berchemia sinica, rubia maillardi, clematis root, moghania root, millettia hirsutissima and alpinia japonica as raw material and pharmaceutical aueptable carrier through a certain preparation process.

Description

technical field [0001] The present invention relates to a kind of medicinal composition which has the functions of expelling wind and dampness, dissipating blood stasis and relieving pain, relaxing tendons and activating collaterals, and is used for the treatment of cold pain in the waist and knees, numbness of limbs, difficulty in stretching and flexion caused by wind-cold-dampness An oral preparation of a pharmaceutical composition prepared from the extracts of the active ingredients of seven traditional Chinese medicines, including Shanfeng, Goucatecha, Sikuaiwa, Clematis, Qianjinba, Fengcheng Spatholobus, and Shanjiang. Background technique [0002] According to the ministerial drug standard WS 3 -Zanshanfeng syrup prepared by the preparation method given in B-2011-95 is a kind of syrup with the functions of expelling wind and dampness, dissipating blood stasis and relieving pain, relaxing tendons and activating collaterals, and is used for cold pain in the waist and kne...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61K36/185A61K9/20A61P29/00
Inventor 曲韵智张宝文
Owner 北京博智绿洲医药科技有限公司
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