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Use of esterified amidates as feed additive

A technology of feed additive and esterified lysine, which is applied in the fields of application, animal feed, animal feed, etc., can solve the problems of reduced bioavailability of feed crystalline amino acids, decreased ability of animal protein synthesis, and loss of feeding value. Achieve the effects of improving animal immunity, improving feed utilization and improving ability

Inactive Publication Date: 2007-01-24
HANGZHOU KINGTECHINA FEED CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, research has found that: (1) when crystalline amino acids (lysine, methionine, threonine, tryptophan) are used in ruminants, they have been decomposed when they pass through the rumen of the animal, losing their original Feeding value; (2) Feed protein-bound amino acids and added free crystalline amino acids have obvious problems of digestion and absorption time difference in aquatic products, poultry and other animals, and the biological utilization of crystalline amino acids for feeding is reduced, resulting in animal protein The ability to synthesize
[0005] Chinese patent ZL200510049911.4 discloses the "Application of Esterified Amino Acids as Feed Additives" applied by our company. However, since esterified amino acids are in liquid state, there are problems such as inconvenient transportation, difficult addition in feed, and high cost, so the application for esterification Patent for the application of amino acid salts as feed additives

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

[0010] Example 1: Application of esterified amino acid salts as feed additives in high-yielding dairy cow feed

[0011] Experimental group feed formulation weight percent: corn 51%, soybean meal 34%, bran 11%, salt 1%, bone meal 3%, vitamin 0.01%, trace element 0.1%, lysine (lysine ethyl ester hydrochloride form ) 0.13%, methionine (methionine ethyl ester hydrochloride form) 0.14%.

[0012] Feed formula for the control group: without adding lysine ethyl ester hydrochloride and methionine ethyl ester hydrochloride, but adding feed crystal lysine and methionine, the addition amount is equal to that of the experimental group, and the rest of the formula and its content are the same as those of the experimental group. The group agrees.

[0013] Sixty healthy Holstein cows with the same weight and age were selected and divided into two groups, the experimental group and the control group, with 30 cows in each group, and 3 replicates in each group, with 10 cows in each replicate, a...

example 2

[0014] Example 2: Application of esterified amino acid salts as feed additives in dairy cows at the peak lactation period

[0015] Experimental group feed formulation weight percent: cornmeal 44%, flax cake 29%, bran 24%, bone meal 3%, vitamin 0.01%, trace element 0.1%, lysine (lysine methyl ester hydrochloride form) 0.15% , methionine (methionine ethyl ester hydrochloride form) 0.15%. .

[0016] Preparation of lysine methyl ester hydrochloride: add 12L of methanol and 1538g of lysine hydrochloride into a 20L reactor. While stirring, dry hydrogen chloride gas is passed into the above suspension until saturated. Lysine hydrochloride gradually dissolves, and the solution is transparent after heating and reflux. After the solution is sealed and left standing for 12 hours, hydrogen chloride and excess methanol are evaporated under reduced pressure. After the solution is concentrated, it is added to cold anhydrous ether. At this time, yellow White crystals were precipitated, wash...

example 3

[0022] Example 3: Application of Esterified Methionine Hydrochloride in Penaeus vannamei Feed

[0023] Experimental group feed formula weight percent: fish meal 34%, soybean meal 28%, peanut meal 8%, flour 18%, squid paste 1%, shrimp shell powder 3%, fish oil 1%, soybean oil 1%, calcium dihydrogen phosphate 1.5%, Zeolite powder 2%, vitamin 1%, trace element 0.3%, salt 0.2%, binder 0.5%, choline chloride 0.3%, methionine (methionine ethyl ester hydrochloride form) 0.2%.

[0024] Feed formula for the control group: no ethyl methionine hydrochloride was added, but crystal methionine for feed was added, the amount added was equal to that of the experimental group, and the rest of the formula and its content were consistent with the experimental group.

[0025] A total of 200 vannamei shrimps that were healthy and of the same size were selected and randomly divided into 2 groups with 100 fish in each group (5 replicates in each group, 20 in each replicate). 3 In the plastic bucket...

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Abstract

The present invention relates to new use of esterified amidates, and is especially the application of esterified amidates in feed. The esterified amidates includes esterified amidate hydrochloride, esterified amidate sulfate and esterified amidate phosphate, which are synthesized with esterified lysine, esterified methionine, esterified threnine or esterified tryptophan with hydrochloric acid, sulfuric acid or phosphoric acid in the equal molar amount. The esterified amidates are added into feed in the amount of 1g to 50Kg each ton. They can raise feed utilization rate by means of the action of the rumen of ruminant, raise the capacity of animal to synthesize protein and raise the immunity of animal.

Description

technical field [0001] The present invention relates to the use of esterified amino acid salts, especially the application of esterified amino acid salts as feed additives. technical background [0002] Amino acids are important components of biological organisms and play a vital role in life phenomena. With the advancement of biological science, human beings understand the physiological functions and metabolic activities in living organisms, and the important biological functions of amino acids in living organisms are becoming more and more clear. Amino acids are extremely important substances for the nutrition, survival and development of living organisms, and play an important role in the regulation of material metabolism and information transmission in living organisms. [0003] The functions of amino acids have always aroused people's strong interest, and they can be widely used in various fields such as medicine, food, agriculture, anim...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23K1/16A23K20/142
Inventor 李浙烽占秀安
Owner HANGZHOU KINGTECHINA FEED CO LTD
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