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Application of Chinese medicine polygala root as in-vitro spermaticide and method for preparing the medicament thereof

A spermicidal and polygala technology, which is applied in the application field of traditional Chinese medicine polygala as an in vitro spermicidal drug, can solve the problems of uncertainty of toxic and side effects, toxic and side effects, and cannot be widely used, and achieves the effects of reliable contraceptive effect and convenient use.

Inactive Publication Date: 2007-05-23
SHANDONG PROVINCIAL FAMILY PLANNING INST OF SCI & TECH
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AI Technical Summary

Problems solved by technology

In response to this situation, there are many reports on the spermicidal drugs of traditional Chinese medicine compositions, but due to the uncertainty of its toxic and side effects, and many reasons such as low spermicidal efficacy, it cannot be widely used so far.
Some compounds have been reported to kill sperm, but because these contraceptives have multiple functions such as bactericidal, virucidal, and spermicidal, and are suitable for areas where sexually transmitted diseases and AIDS are common, there are still toxic and side effects for contraceptives that are purely spermicidal

Method used

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Embodiment Construction

[0011] The Chinese medicine polygala of the present invention is used as a medicine for killing sperm in vitro, wherein the medicine polygala is used as a drug raw material for killing sperm in vitro, and its extract is made into emulsion or suppository for vaginal contraceptive medicine. The excipients and dosages used in the emulsion and suppository are conventional pharmaceutical excipients and dosages.

[0012] The preparation method of the traditional Chinese medicine Polygala as a medicine for killing sperm in vitro is as follows: the Chinese medicine raw material Polygala is ground, placed in 0.9% normal saline and soaked for 1.5-2.5 hours, preferably 2 hours, and the ratio of Polygala raw material to normal saline is 100 grams : 900-1200 milliliters, preferably 100 grams: 1000 milliliters, placed in a metal bath at 100°C and heated for 15-40 minutes, preferably 30 minutes, after taking out, filtering and removing slag to obtain Polygala extract, and Polygala extract wit...

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Abstract

The invention relates to a method for using polygala root to kill sperm externally, wherein it uses polygala root as the drug to kill sperm externally, makes extractive into emulsion or suppositorium, to be used in vagina contraceptive. And its production comprises that: breaking polygala root, immerges in 0.9% normal saline, while their ration is 100g:900-1200ml, to be heated in 100Deg. C metal bath; taking out, filtering out the slag. The inventive polygala root extractive has non stimulation on vaginal mucosa, without damage on vaginal bacterial and side effect. And it has low cost.

Description

technical field [0001] The invention relates to a traditional Chinese medicine, and relates to the application of the traditional Chinese medicine polygala as an in vitro spermicide and a method for preparing the medicine. Background technique [0002] Among the contraceptive measures, intrauterine device, tubal ligation and vasectomy will all cause harm to the human body. For this reason, people use condoms or oral contraceptives to minimize the damage. However, long-term oral contraceptives will cause harm to the human body. Produce bigger side effect, and the use of condom still has certain probability of conception except that sensory property is poor, so this area is trying hard to study the medicine of in vitro spermicide again in recent years. The drugs used to kill sperm in vitro were the first to use imported drugs, and later more varieties were launched in China. Since the main ingredients of the drugs are all western medicines, it was found during use that these d...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/69A61P15/18
Inventor 邱毅王磊光贾颐舫张爱东杨丹彤李欣迎
Owner SHANDONG PROVINCIAL FAMILY PLANNING INST OF SCI & TECH
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