Lipid-regulating agent and use thereof

Abstract

The object of the present invention is to provide a lipid-regulating agent or a composition for regulating the amount of lipids comprising the agent. The present invention solves the above object by providing a lipid-regulating agent comprising a cyclic tetrasaccharide and / or its saccharide-derivative(s) and a composition for regulating the amount of lipids comprising the lipid-regulating agent.

Description

TECHNICAL FIELD [0001] The present invention relates to a novel lipid-regulating agent and use thereof, particularly, to a novel lipid-regulating agent comprising a non-reducing saccharide where four glucose molecules are bound via alternating α-1,3 and α-1,6 linkages, i.e., a cyclic tetrasaccharide, represented by the formula of cyclo {→6)-α-D-glucopyranosyl-(1→3)-α-D-glucopyranosyl-(1→6)-α-D-glucopyranosyl-(1→3)-α-D-glucopyranosyl-(1→) (hereinafter, simply abbreviated as “CTS” in this specification), and / or its saccharide-derivative(s) as an effective ingredient(s), and to a composition for regulating the amount of lipids, comprising the lipid-regulating agent. BACKGROUND ART [0002] In recent years, accompanying with the progress in living standard, dietary habits have altered to Western-style in many countries including Japan. Therefore, we tend to intake excess calories and lipids compared with a traditional dietary habit. As a result, patients and potential patients of lifestyl...

AI Technical Summary

Benefits of technology

[0008] To solve the above objects, the present inventors have studied on a lipid-regulating agent comprising a saccharide as an effective ingredient for a long period of time. As a result, the present inventors found that CTS and / or its saccharide-derivative(s) effected on the regulation of the amount of lipids, and then inhibits the increase of body weight, and regulates the amount of cholesterol to the ordinary level or very close to it. The present inventors accomplished the present invention by establishing a novel lipid-regulating agent and a composition for regulating the amount of lipids, comprising the lipid-regulating agent.

Problems solved by technology

Among those, adiposis, which is caused by the excess increase of lipids in the living body, is a risk factor of those lifestyle-related diseases and is recognized as a large problem on human health.

Also, women in and / or after adolescence tend to hate the corpulence.

Some of them get out of order of hormone valance and cause critical diseases such as osteoporosis by the diet with wrong methods, causing excess burden on the body.

However, many people are forced to abandon such methods because they require pointed leadings and a long period.

Also, the dietary restriction is not preferable from the viewpoint of mental health.

Although taking drugs is effective for curing or preventing adiposis and hyperlipemia, the side-effect and cost of the drugs cause problems.

However, in the case of using those ingredients for materials of foods and beverages, some of those ingredients are food materials having disadvantages of deteriorating the taste, flavor, and mouthfeel; being not effective without taking in a relatively large amount; or causing diarrhea depending on the physical condition or the predisposition.

However, in all those literatures, there is no disclosure about the lipid-regulating activity of CTS and / or its saccharide-derivative(s) or a composition comprising those saccharides.