Chromatography pump
a chromatography pump and chromatography technology, applied in the direction of positive displacement pump components, liquid fuel engine components, etc., can solve the problems of reducing the performance of the chromatography pump, affecting the flow rate of the solution, and air bubbles prone to be trapped in the chromatography pump cylinder, etc., to achieve the effect of compact design
Inactive Publication Date: 2013-10-03
GE HEALTHCARE BIO SCI CORP
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Benefits of technology
The invention aims to provide a chromatography pump with automatic purging, eliminating the need for manual means. Additionally, it facilitates the transport of air bubbles through the pump.
Problems solved by technology
However, to some extent air bubbles tend to be trapped within the chromatography pump cylinder even if the purging arrangement has removed the major volume of air held in the chromatography pump.
The air bubbles trapped within the chromatography pump reduces the performance of the chromatography pump, so that the pressure and flow of the solution will fluctuate.
This will influence on the overall chromatography mixing process, so that less accurate results will be achieved.
Method used
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Embodiment Construction
[0028]FIG. 1 shows a diagrammatic cross section view of a prior art chromatography pump 101, which comprises a cylinder 102 in which a piston 104 is arranged for a reciprocating movement. The reciprocating movement of the piston 104 is generated by a driving means 106, such as an electric motor. A front element 108 is provided with a cylinder head area 110 which together with the cylinder 102 and the piston 104 defines a cylinder space 112. An inlet valve 114 and an outlet valve 116 in form of check valves are arranged in the front element 108. An inlet channel 118 is arranged in the front element 108 between the inlet valve 114 and the cylinder head area 110, and an outlet channel 120 is arranged in the front element 108 between the cylinder head area 110 and the outlet valve 116. When the piston 104 moves in the left direction in FIG. 1 a liquid 122 held in a schematically disclosed container 124 is sucked into the cylinder space 112 through the inlet valve 114 and the inlet chann...
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The invention relates to a chromatography pump, comprising a cylinder (202, 402) in which a piston (204, 404) is arranged for a reciprocating movement; a front element (208) provided with a cylinder head area (210) which together with the cylinder (202, 402) and the piston (204, 404) defines a cylinder space (212); an inlet valve (214) and an outlet valve (216) arranged in the front element (208); an inlet channel (218) arranged in the front element (208) between the inlet valve (214) and the cylinder head area (210); an outlet channel (220) arranged in the front element (208) between the cylinder head area (210) and the outlet valve (216). The inlet channel (218) and outlet channel (220) extend in a substantially straight direction, so that air bubbles (234) are prevented from being trapped within the inlet and outlet channels (218, 220).
Description
TECHNICAL FIELD[0001]The present invention relates to a chromatography pump according to the preamble of claim 1.[0002]Chromatography is a chemical process for identifying and quantifying compositions held in a sample and also for purification and extraction of compositions. In the process, compositions in a solution are separated from each other as the solution moves through a stationary material held in a column.[0003]The solution is pumped under high pressure through the stationary material in the column by one or several chromatography pumps.BACKGROUND ART[0004]In chromatography and especially in liquid chromatography often only very small samples of the material to be analyzed or purified are available. The process during mixing gradients of two different liquids is also sensitive for rapid changes in the flow and pressure of solution as it moves through the stationary material in the column. For this reason the chromatography pump system has to be very accurate in order to ach...
Claims
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Patent Timeline
Login to View More IPC IPC(8): F04B53/16
CPCF04B11/0033F04B53/16F04B53/06
Inventor SALVEN, OWEOLOVSSON, BJORNLUNDKVIST, MATSKRANSE, JAN
Owner GE HEALTHCARE BIO SCI CORP