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Multiplexed / pathlength resolved noninvasive analyzer apparatus and method of use thereof

a non-invasive, multi-path technology, applied in the field of non-invasive analyzers, can solve the problems of diabetes being the leading cause of death and disability worldwid

Inactive Publication Date: 2015-02-12
ZYOMED
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Currently, diabetes is a leading cause of death and disability worldwide.

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  • Multiplexed / pathlength resolved noninvasive analyzer apparatus and method of use thereof
  • Multiplexed / pathlength resolved noninvasive analyzer apparatus and method of use thereof
  • Multiplexed / pathlength resolved noninvasive analyzer apparatus and method of use thereof

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Embodiment Construction

[0048]The invention comprises a noninvasive analyzer apparatus and method of use thereof using at least one two-dimensional near-infrared detector array.

[0049]In another embodiment, an apparatus and method of use thereof is described using a plurality of time resolved sample illumination zones coupled to at least one two-dimensional detector array monitoring a plurality of detection zones linked to the sample illumination zones.

[0050]In still another embodiment, an apparatus and method of use thereof is described using acquisition of noninvasive mapping spectra of skin and subsequent optical / optical path reconfiguration for subsequent subject specific data collection.

[0051]For example, a near-infrared noninvasive analyzer is configured with a first optical configuration used to map an individual and / or group of individuals through use of mapping spectra. The mapping spectra are analyzed and used to reconfigure the optical setup of the analyzer to a second optical configuration suite...

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Abstract

A noninvasive analyzer apparatus and method of use thereof is described using a plurality of time resolved sample illumination zones coupled to at least one two-dimensional detector array monitoring a plurality of detection zones. Control of illumination times and / or patterns along with selected detection zones yields pathlength resolved groups of spectra. Sectioned pixels and / or zones of the detector are optionally filtered for different light throughput as a function of wavelength. The pathlength resolved groups of spectra are subsequently analyzed to determine an analyte property. Optionally, in the mapping and / or collection phase, incident light is controllably varied in time in terms of any of: sample probe position, incident light solid angle, incident light angle, depth of focus, energy, intensity, and / or detection angle. Optionally, one or more physiological property and / or model property related to a physiological property is used in the analyte property determination.

Description

CROSS REFERENCES TO RELATED APPLICATIONS[0001]This application:[0002]is a continuation-in-part of U.S. patent application Ser. No. 13 / 941,411 filed Jul. 12, 2013, which is a continuation-in-part of U.S. patent application Ser. No. 13 / 941,389 filed Jul. 12, 2013, which is a continuation-in-part of U.S. patent application Ser. No. 13 / 941,369 filed Jul. 12, 2013, which claims the benefit of:[0003]U.S. provisional patent application No. 61 / 672,195 filed Jul. 16, 2012;[0004]U.S. provisional patent application No. 61 / 700,291 filed Sep. 12, 2012; and[0005]U.S. provisional patent application No. 61 / 700,294 filed Sep. 12, 2012; and[0006]claims the benefit of U.S. provisional patent application No. 61 / 845,926 filed Jul. 12, 2013,[0007]all of which are incorporated herein in their entirety by this reference thereto.TECHNICAL FIELD OF THE INVENTION[0008]The present invention relates to a noninvasive analyzer using a sample mapping phase to generate instrumentation setup parameters followed by a...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61B5/145A61B5/00A61B5/1455
CPCA61B5/14532A61B5/6801A61B5/1455A61B5/14552G01N2021/4742G01N2021/4747G01N2201/0826G01N21/474A61B5/0022A61B5/1079G01J3/42
Inventor NOVOTNY, VLADGULATI, SANDEEPGEORGE, THOMASRUCHTI, TIMOTHYABUL-HAJ, ALANHAZEN, KEVIN H.
Owner ZYOMED
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