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Multiplexed / pathlength resolved noninvasive analyzer apparatus and method of use thereof

a non-invasive, multi-path technology, applied in the field of non-invasive analyzers, can solve the problems of diabetes being the leading cause of death and disability worldwid

Inactive Publication Date: 2015-02-12
ZYOMED
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

The solution provides accurate and precise noninvasive glucose concentration measurements, reducing errors and enhancing the ability to manage diabetes by optimizing photon interaction with skin layers, thereby improving patient care.

Problems solved by technology

Currently, diabetes is a leading cause of death and disability worldwide.

Method used

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  • Multiplexed / pathlength resolved noninvasive analyzer apparatus and method of use thereof

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Embodiment Construction

[0048]The invention comprises a noninvasive analyzer apparatus and method of use thereof using at least one two-dimensional near-infrared detector array.

[0049]In another embodiment, an apparatus and method of use thereof is described using a plurality of time resolved sample illumination zones coupled to at least one two-dimensional detector array monitoring a plurality of detection zones linked to the sample illumination zones.

[0050]In still another embodiment, an apparatus and method of use thereof is described using acquisition of noninvasive mapping spectra of skin and subsequent optical / optical path reconfiguration for subsequent subject specific data collection.

[0051]For example, a near-infrared noninvasive analyzer is configured with a first optical configuration used to map an individual and / or group of individuals through use of mapping spectra. The mapping spectra are analyzed and used to reconfigure the optical setup of the analyzer to a second optical configuration suite...

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Abstract

A noninvasive analyzer apparatus and method of use thereof is described using a plurality of time resolved sample illumination zones coupled to at least one two-dimensional detector array monitoring a plurality of detection zones. Control of illumination times and / or patterns along with selected detection zones yields pathlength resolved groups of spectra. Sectioned pixels and / or zones of the detector are optionally filtered for different light throughput as a function of wavelength. The pathlength resolved groups of spectra are subsequently analyzed to determine an analyte property. Optionally, in the mapping and / or collection phase, incident light is controllably varied in time in terms of any of: sample probe position, incident light solid angle, incident light angle, depth of focus, energy, intensity, and / or detection angle. Optionally, one or more physiological property and / or model property related to a physiological property is used in the analyte property determination.

Description

CROSS REFERENCES TO RELATED APPLICATIONS[0001]This application:[0002]is a continuation-in-part of U.S. patent application Ser. No. 13 / 941,411 filed Jul. 12, 2013, which is a continuation-in-part of U.S. patent application Ser. No. 13 / 941,389 filed Jul. 12, 2013, which is a continuation-in-part of U.S. patent application Ser. No. 13 / 941,369 filed Jul. 12, 2013, which claims the benefit of:[0003]U.S. provisional patent application No. 61 / 672,195 filed Jul. 16, 2012;[0004]U.S. provisional patent application No. 61 / 700,291 filed Sep. 12, 2012; and[0005]U.S. provisional patent application No. 61 / 700,294 filed Sep. 12, 2012; and[0006]claims the benefit of U.S. provisional patent application No. 61 / 845,926 filed Jul. 12, 2013,[0007]all of which are incorporated herein in their entirety by this reference thereto.TECHNICAL FIELD OF THE INVENTION[0008]The present invention relates to a noninvasive analyzer using a sample mapping phase to generate instrumentation setup parameters followed by a...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61B5/145A61B5/00A61B5/1455
CPCA61B5/14532A61B5/6801A61B5/1455A61B5/14552G01N2021/4742G01N2021/4747G01N2201/0826G01N21/474A61B5/0022A61B5/1079G01J3/42
Inventor NOVOTNY, VLADGULATI, SANDEEPGEORGE, THOMASRUCHTI, TIMOTHYABUL-HAJ, ALANHAZEN, KEVIN H.
Owner ZYOMED
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