Methods for diagnosing osteoarthritis

a technology of osteoarthritis and prognosis, applied in the field of osteoarthritis prognosis, can solve the problems of incomplete knowledge of the biology of oa, the functional importance of these susceptibility loci has not yet been confirmed,
US20150153362A1Inactive Publication Date: 2015-06-04VALORISATION HSJ LLP
1 Cites 1 Cited by

Patent Information

Authority / Receiving Office
US · United States
Patent Type
Applications(United States)
Current Assignee / Owner
VALORISATION HSJ LLP
Publication Date
2015-06-04
Estimated Expiration
Not applicable · inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

A method of predicting the risk of developing osteoarthritis (OA) comprising: (a) measuring the nuclear cellular level of prohibitin (PHB-1) in nucleated cells present in a blood sample from a subject having or suspected of having OA; and (b) comparing said nuclear cellular level to that corresponding to a control sample; and (c) identifying the subject as being at risk of developing OA when the nuclear cellular level of said PHB-1 in said blood sample is higher than in the control sample.
Need to check novelty before this filing date? Find Prior Art

Description

CROSS REFERENCE TO RELATED APPLICATIONS

[0001] This application is a continuation of U.S. patent application Ser. No. 12 / 447,152, which is a National Entry Application of PCT Application Serial No. PCT / CA2007 / 001901 filed on Oct. 25, 2007 and published in English under PCT Article 21(2), which itself claims priority on U.S. Provisional Application Ser. No. 60 / 854,077 filed on 25 Oct. 2006. All documents above are incorporated herein in their entirety by reference.FIELD OF THE INVENTION

[0002] The present invention relates to methods of prognosing osteoarthritis, methods of selecting compounds and kits therefore.REFERENCE TO SEQUENCE LISTING

[0003] Pursuant to 37 C.F.R. 1.821(c), a sequence listing is submitted herewith as an ASCII compliant text file named 12810—230_ST25, that was created on Dec. 11, 2014 and having a size of 34 kilobytes. The content of the aforementioned file is hereby incorporated by reference in its entirety.BACKGROUND OF THE INVENTION

[0004] The etiology of (OA), the m...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More