The present invention relates to a coupling arrangement for a system for endotracheal ventilation of a patient, which system comprises an endotracheal tube and a manifold (100) configured for allowing ventilation of the patient via said endotracheal tube, which manifold (100) has a first coupling means (300) with an axial extent (400) and with engagement means (330); and which endotracheal tube has a second coupling means (400) with an axial extent and with engagement means (420); wherein the coupling arrangement is configured to produce, when the first (300) and the second (400) coupling means are moved together in the axial 360 direction, a locking engagement between the engagement means (33, 420). The invention is characterised in that the first coupling means (300), in the axial direction, comprises an exterior screw thread (320); and that the second coupling means (400) comprises an exterior abutment face (430); that the coupling arrangement also comprises a disengagement means (350) configured for cooperating with said screw thread (320); and that the disengagement means (350) and the screw thread (320) are configured for allowing an axial movement of the disengagement means (350) from a first position, in which said engagement means (330, 420) are in locking engagement, to a second position in which the disengagement means (350) can influence the abutment face (430) by an axial force for releasing the locking engagement.