38 results about "Oral soft tissues" patented technology

The invention relates to the technical field of oral medical treatment, in particular to an oral disease analysis method and system based on AI intelligent recognition. Comprising the following steps that oral cavity three-dimensional surface data are obtained through an oral scanning module integrated with a dental chair, and the oral scanning module adopts a structured light coding and multi-view fusion algorithm; an oral soft tissue high-definition image is collected through an endoscope module, and an AI analysis unit is arranged in an endoscope to recognize mucous membrane lesion features in real time; calling CBCT image data of the patient, and aligning a three-dimensional image with oral scanning data through a spatial registration algorithm; the mouth scanning data, the endoscope image and the CBCT data are subjected to multi-modal fusion by adopting a dynamic weight fusion mechanism. According to the scheme, the problem of accurate registration of cross-modal data, the lack of a dynamic quality evaluation mechanism of heterogeneous data and the real-time collaboration bottleneck of dispersed equipment can be solved.

The invention provides an adjustable oral soft tissue traction fixing device for an apical surgery. The adjustable oral soft tissue traction fixing device comprises a dentition fixing component, a lower jaw fixing component and a soft tissue traction fixing component, the dentition fixing component is used for being fixed in the oral cavity of a subject and located at the upper end of the dentition where the operation teeth are located. The dentition fixing component comprises a buckle plate and an insertion rod; a groove is formed in the lower side of the buckle plate, and the buckle plate is buckled on the dentition through the groove; the upper end of the insertion rod is fixed to the first side of the buckle plate. The lower jaw fixing component comprises a bottom plate and a side plate; the bottom plate and the side plate are connected to form an L shape; the lower jaw fixing component is used for being fixed outside the oral cavity of a subject; first insertion holes are formed in the side plates in the vertical direction; the lower part of the inserting rod is inserted and fixed in the first inserting hole; the first end of the soft tissue traction fixing component can be adjustably fixed to the lower jaw fixing component, and the second end of the soft tissue traction fixing component is used for extending into the oral cavity of a subject so as to achieve traction and fixing of gingival soft tissue flaps.

The invention provides an oral cavity three-dimensional model texture mapping method and device for soft tissue. The method comprises the following steps: scanning and collecting a two-dimensional image and three-dimensional point cloud data of an oral cavity; carrying out panoramic fusion and soft and hard tissue segmentation processing on the two-dimensional image; adopting an off-line parameterization method for the separated soft tissue part, and reconstructing a soft tissue three-dimensional model by setting deformation parameters and based on iterative optimization of segmented fusion; and mapping the texture information of the two-dimensional image to the three-dimensional model, and optimizing and screening the texture information through a probability graph to complete the three-dimensional model texture mapping of the oral soft tissue. Through a differentiated and efficient data processing method, rapid and accurate oral cavity three-dimensional model reconstruction and texture mapping are realized.

The invention provides a composition for repairing oral soft tissue injury. The composition for repairing the oral soft tissue injury comprises amelogenin, a plant extract and a zinc ion compound, and the plant extract comprises at least one of a liquorice extract, a scindapsus aureus flower extract and a fructus piperis longi extract. The composition for repairing oral soft tissue injury can effectively repair oral soft tissue cells, inhibit release of inflammatory factors and improve halitosis, so that oral soft tissue injury symptoms are improved, injury healing is promoted, and fresh breath is kept.

The utility model relates to a bite block which comprises a U-shaped bite block body, a first via hole penetrating through the inner side face and the outer side face of the U-shaped bite block body is formed near the bending position of the U-shaped bite block body, and an air supply pipe guide pipe penetrates through the first via hole. A fixing mechanism is arranged at the position, located at the first via hole, of the outer side face of the U-shaped bite block body and used for being fixedly connected with the tracheal catheter. The dental pad provided by the utility model can avoid deformation of a tracheal catheter, can avoid damage to teeth of a patient in an operation, and can prevent bite injury of tongue and oral soft tissues; the first via hole is formed near the bending position of the U-shaped bite block body, the fixing mechanism is arranged at the position, located at the first via hole, of the outer side face of the U-shaped bite block body, and after a tracheal catheter penetrates through the first via hole, the tracheal catheter is fixed through the fixing mechanism, so that fixation between the tracheal catheter and the bite block is achieved.

The invention discloses a personalized complete denture precise manufacturing method based on a multi-modal digital technology, and relates to the technical field of oral restoration engineering and digital medical treatment. According to the method, firstly, three-modal data acquisition of oral soft tissue, facial aesthetics and alveolar bone anatomy is completed through an intraoral scanner, surface scanning equipment and CBCT; performing precise registration through an ICP algorithm to generate an integrated model; a virtual jaw frame and intelligent tooth arrangement software are combined to complete personalized design; for special cases, a transition / temporary denture and a biocompatibility tissue regulator are adopted to realize dynamic adaptation; and finally, completing false tooth manufacturing and verification through 3D printing or five-axis cutting. The method solves the problems that a traditional method is low in precision, weak in special case treatment and the like, achieves anatomy-function-aesthetics synergistic repair of the false tooth, and has the advantages of being high in adaptation degree, short in period and less in revival.

The invention belongs to the field of protein hydrogel, and relates to protein adhesive hydrogel for promoting diabetic oral soft tissue injury repair and a preparation method of the protein adhesive hydrogel. The hydrogel is prepared by mixing an aqueous solution of recombinant fusion protein and an aqueous solution of polyethylene glycol bissuccinimide succinate. The sequence of the recombinant fusion protein is as shown in SEQ ID NO: 1: [PAATAVSHTTHAP (VPGKG) 5] 36. The hydrogel disclosed by the invention has good biocompatibility and excellent adhesion performance, can form a lasting antibacterial barrier, and is electrostatically combined with free DNA (Deoxyribonucleic Acid) in NETs, so that inflammatory factor expression induced by the NETs is inhibited, and finally diabetes wound healing is accelerated.

The invention discloses a rapid-absorption collagen repair membrane and a preparation method thereof, and relates to the technical field of biological materials. The repairing membrane is of a double-layer structure and comprises a purified collagen layer and an absorbable polymer spinning layer loaded with inorganic nanoparticles. The preparation method comprises the following steps: purifying animal skin to obtain a purified collagen layer; the preparation method comprises the following steps: respectively dispersing akermanite and hydroxyapatite nanoparticles, and mixing; adding the mixed dispersion liquid into the absorbable polymer solution to obtain a composite spinning solution; spinning the composite spinning solution on the surface of the collagen layer by adopting an electrostatic spinning method to form a spinning layer; and drying to obtain the repairing film. According to the invention, by regulating and controlling the variety, proportion, crystallinity and spatial distribution of the inorganic particles, the synergistic enhancement of mechanical properties and biological activity is realized, so that the repair film has pH-responsive graded release ability, can automatically adjust degradation behavior according to inflammation intensity, actively adapts to microenvironment, and has good application prospects. The method can be widely applied to the fields of oral soft tissue repair, periodontal wound covering and the like.

Mouth Mirror Designed for Patients with Sensitive Oral Soft Tissues

The invention provides an oral soft tissue recognition method, device and equipment and a storage medium, and relates to the technical field of oral scanning. The method comprises the following steps: firstly, acquiring an original oral cavity endoscope image, then performing multi-level feature extraction on the original oral cavity endoscope image, and constructing a multi-scale feature pyramid; performing over-domain adaptive processing on the multi-scale feature pyramid, and synchronously performing image segmentation processing and depth estimation processing based on the processed multi-scale feature pyramid to obtain segmentation features; and finally, based on the segmentation features, obtaining an oral soft tissue segmentation result, thereby realizing high-quality oral soft tissue segmentation while ensuring real-time performance.

The invention provides a composition for oral rehabilitation and a preparation method thereof, and belongs to the technical field of oral care. The composition for repairing the oral cavity is prepared from glaze protein, polylysine, ceramide NP, a plant extract, a penetration enhancer, a slow release agent, a preservative and a solvent. The amelogenin dominates cell proliferation and differentiation and tissue regeneration and provides core repair power; the polylysine promotes proliferation, resists bacteria and strengthens the mechanical strength of newborn tissues; the ceramide NP reconstructs the mucosal barrier, reduces component loss and external stimulation, and stabilizes and restores the environment. Through compounding of the three components, the oral soft tissue injury repair efficiency can be remarkably improved, the healing period is shortened, and the recurrence rate is reduced. Experiments show that the composition can effectively promote cell proliferation and migration, inhibit release of inflammatory factors and remarkably shorten the wound healing period, and the repairing effect is excellent.

The invention relates to a bionic collagen matrix with a density gradient double-layer structure, and belongs to the technical field of medical materials. The collagen matrix takes telopeptide collagen derived from mammalian dermis or achilles tendon as a main component, and comprises a double-layer structure of a compact layer and a loose layer, and the compact layer is smooth in surface and compact in structure, so that cell migration can be blocked, and a certain protection effect is achieved; the loose layer is of a porous structure, cell ingrowth and blood clot stabilization are facilitated, and a support is provided for tissue repair. The preparation method of the biological membrane comprises the following steps: preparing telopeptide-removed collagen gel, preparing collagen sponge, preparing a collagen tissue regeneration membrane, and compounding the collagen tissue regeneration membrane and the collagen sponge into an integrated double-layer structure through bonding, drying and crosslinking. The double-layer structure simultaneously meets the double requirements of barrier protection and tissue regeneration, the process is simple and controllable, and the double-layer structure is suitable for clinical scenes such as oral soft tissue repair, alveolar ridge reconstruction and tooth extraction pit coverage.

The invention discloses a preparation process and application of potassium calcium sodium phosphosilicate fluoride, and belongs to the technical field of biological materials. By optimizing the low-temperature fluoride raw material and the bioactive glass powder and under the sintering treatment process, high fluorine loading capacity can be obtained, the fluorine element is combined with the bioglass in a chemical bond form, the stability is higher, and the application effect of the bioglass is guaranteed; and low-temperature sintering treatment is low in energy consumption, large-scale production can be achieved, and operability is high. Besides, the fluorinated sodium potassium calcium phosphosilicate prepared by the invention is high in biological safety, can play remarkable roles in inhibiting bacteria, preventing dental caries and tooth sensitivity symptoms, promoting oral soft tissue healing, inhibiting gingivitis and freshening breath when being applied to preparation of medical oral products and daily chemical products, can also be applied to preparation of foods, and has a wide application prospect. Especially in the preparation of betel nuts, as an active material, the betel nuts can relieve tooth sensitivity symptoms, promote oral soft tissue healing and inhibit gingivitis.

The present invention provides an oral soft tissue repair device and method based on a biological cell scaffold, relating to the field of biological oral technologies. The device includes a bionic adaptive biological cell scaffold, a multi-dimensional precision 3D printing system, and an intelligent implantation and regulation device. The bionic adaptive biological cell scaffold is made of a composite of collagen, hyaluronic acid, and a biodegradable poly(lactic-co-glycolic acid) copolymer. The bionic adaptive biological cell scaffold has a multi-layer spiral pore network, and the inner wall of the pore network is embedded with microfluidic channels. Chemical-sensitive microvalves are arranged in the microfluidic channels. By integrating the bionic adaptive biological cell scaffold, the multi-dimensional precision three-dimensional printing system, and the intelligent implantation and regulation device, and combining finite element analysis and the particle swarm optimization algorithm, the present invention can accurately simulate the chewing dynamics and saliva secretion characteristics of patients, effectively solving the problem of the lack of dynamic adaptability in the static design of traditional scaffolds.

The utility model provides a shell-shaped appliance which comprises an appliance body and further comprises a first reinforcing film, and the first reinforcing film is connected to at least part of the wall face, facing the tongue side, of the appliance body. By adopting the structural form, direct contact between the first reinforcing film and oral mucosa is avoided, so that stimulation and friction of the first reinforcing film to oral soft tissue are reduced, the probability of mucosa injury or ulcer is reduced, and the use experience of customers is improved. Besides, the first reinforcing film is connected to the wall surface, facing the tongue side, of the shell-shaped appliance, so that the force application point of the first reinforcing film is closer to the impedance center of the teeth, the torque and the moving direction of the teeth can be controlled, and the correction speed and the correction effect are improved.

The utility model relates to the technical field of mouth rehabilitation, and discloses a comprehensive invisible removable denture with a local metal support, which comprises a support, an invisible base and an implant denture, the support comprises a main body frame and a connecting frame, and the invisible base comprises an upper invisible base and a lower invisible base. The implant denture comprises an artificial tooth root connected with the invisible denture, an artificial tooth crown connected with the artificial tooth root and an adjusting screw which penetrates through an abutment in the artificial tooth crown and is used for adjusting the height and the angle of the implant denture. Due to the design of the invisible base plate, the direct contact with oral soft tissues is reduced, the discomfort is reduced, and the wearing comfort is improved. Meanwhile, the false tooth can be conveniently taken off and worn, is convenient to clean and maintain, and is beneficial to maintenance of oral hygiene. The design of the implant denture allows the height and the angle to be adjusted through the adjusting screw, so that the correct occlusion relationship with other teeth in the oral cavity is ensured, the chewing efficiency is improved, and meanwhile, the displacement of adjacent teeth and the degeneration of soft and hard tissues in the oral cavity are reduced.

The invention discloses a cembrane diterpenoid compound as well as a preparation method and application thereof, and relates to the technical field of natural compounds. The cembrane diterpenoids have a structural formula as shown in formulas 1-9, and the preparation method comprises the following steps: firstly extracting and coarsely separating cigar tobacco leaves, and then finely separating and purifying to obtain the cembrane diterpenoids. The cembrane diterpenoids which are not reported are extracted and separated from cigar tobacco leaves, and the compounds 1-9 are proved to be capable of promoting proliferation of human oral mucosa fibroblasts and have a certain effect on healing of oral soft tissue defects.

The invention provides an injection for treating cat stomatitis through oral soft tissue injection. The active ingredients of the injection comprise glucocorticoid and B vitamins, and also comprise mesenchymal stem cells at the same time. According to the invention, the mesenchymal stem cells, the glucocorticoid and the vitamin B are combined as the active ingredient of the injection for biological medicine preparation for the first time, so that the long-term effect and stability of the inflammation inhibition and tissue repair functions of the mesenchymal stem cells are fully exerted, and meanwhile, the characteristic of quick inflammation inhibition effect of the glucocorticoid is utilized; the defects that glucocorticoid is large in side effect after being used for a long time and the condition is repeated after medicine withdrawal are overcome, so that the treatment effect on stomatitis is remarkably improved, and the treatment period is greatly shortened; furthermore, the active ingredients are creatively injected into soft tissues of the oral cavity of an affected cat in a multi-point micro-injection manner in an oral soft tissue injection manner, and a better treatment effect is realized by utilizing low-dose and short-term mesenchymal stem cells and glucocorticoid, so that the technical difficulty in treating the cat stomatitis is overcome.

The invention relates to the technical field of intelligent electric protector control, and discloses an electric toothbrush automatic start-stop control method based on oral cavity multi-sensor fusion and a toothbrush, the method comprises the following steps: collecting proximity sensing and ambient light illumination signals, and switching to an active detection mode when the signals accord with oral cavity darkroom characteristics; then the motor is controlled to generate micro-amplitude vibration, and the load damping characteristic quantity of the motor phase current and the optical-mechanical coupling coefficient obtained through demodulation by using the detection frequency are extracted; when it is judged that the load damping characteristic quantity and the optical-mechanical coupling coefficient both exceed a set threshold value, it is confirmed that effective contact is established between the brush head and oral soft tissue, and a motor is controlled to be started and enter a normal operation mode; and during operation, the ambient light change rate is monitored in real time, and the motor is controlled to stop when the shift-out action is recognized. According to the invention, through a multi-dimensional physical contact verification mechanism, false start splashing and invalid idling in a non-oral environment are effectively prevented.

The invention discloses a pharmaceutical composition for relieving orthodontic pain and a preparation method of various dosage forms of the pharmaceutical composition. The pharmaceutical composition for relieving orthodontic pain comprises vanillin or a pharmaceutically acceptable derivative thereof, and pharmaceutical auxiliary materials. Dosage forms of the pharmaceutical composition comprise a gel type gargle, a foam type gargle and an aromatherapy agent. The gel type gargle comprises the following raw materials in parts by weight: 0.5-3 parts of vanillin, 1-6 parts of a gel matrix, 0.05-0.2 part of an antibacterial agent, 0.5-2 parts of an anti-sensitive agent, 5-10 parts of a humectant, 0.5-2 parts of a solubilizer, 0.1-0.5 part of a sweetening agent, 0.05-0.1 part of a preservative, 0.1-0.5 part of a pH regulator, 0.5-18 parts of ethanol and the balance of deionized water, wherein the sum of the parts by weight of the raw materials is 100. Through the unique texture, the contact time of vanillin in the oral cavity is prolonged, the action effect of vanillin in the oral cavity is improved, so that tooth and oral cavity soft tissue pain caused in the orthodontic treatment process is better relieved, safety and no side effect are achieved, and the treatment comfort of a patient is improved. In addition, the preparation process is simple, and only stirring is needed under the conditions of heating and room temperature until complete dissolution.

The utility model relates to a cleaning unit, a cleaning unit group and a configuration box capable of removing redundant adhesive, the cleaning unit comprises a cleaning part with a hollow ring hole structure, and the section of a hollow ring hole is matched with the section of a tooth, so that the cleaning part can be attached to a narrow gap between a bridge tissue surface and gingiva, and the redundant adhesive on a linear edge is effectively removed; the cleaning unit further comprises an operation structure. The cleaning part and the operation structure are integrally made of elastic materials, so that the cleaning unit can deform when making contact with gingiva and oral cavity soft tissue, and scratching or stabbing possibly caused by rigid instruments is avoided. The operating structures are ear wings which are designed on two sides of the cleaning part and are convenient for clamping operation by two hands; or the operating structure is a finger ring which is designed on one side of the cleaning part and is convenient for single-hand operation, so that the doctor can select two-hand clamping or single-hand operation according to actual requirements during operation, and the flexibility and convenience of use are greatly improved.

This invention discloses a teeth whitening product containing piezoelectric materials. The invention uses piezoelectric materials with a piezoelectric effect as the whitening ingredient in the teeth whitening product. By contacting the teeth with the whitening product and applying pressure to the tooth surface, the piezoelectric properties of the material are activated, generating a large number of active groups that degrade stains on the tooth surface, achieving teeth whitening. The teeth whitening product of this invention is safe and non-toxic, the teeth whitening method is simple to operate, it does not damage oral soft tissues, nor does it damage the enamel layer on the tooth surface, it does not harm the tooth structure, and it can achieve long-lasting and effective teeth whitening results.

This invention relates to the fields of biomedical engineering and regenerative medicine, and particularly to a plasma matrix composite membrane activated by autologous keratinized epithelial tissue fragments, its preparation method, and its applications. The composite membrane is obtained by mixing autologous keratinized epithelial tissue fragments with a liquid autologous plasma matrix in a specific ratio, utilizing tissue factors on the surface of the tissue fragments to trigger platelet activation, spontaneously forming a gel, and then pressing it into a membrane. This invention is the first to utilize the biointerface of autologous keratinized epithelial tissue fragments to activate platelets, eliminating the need for exogenous thrombin and achieving completely autologous in-situ gelation. The composite membrane formed after pressing possesses excellent mechanical properties and barrier function, and can be prepared in a single operation in the operating room without the need for in vitro cell culture. The composite membrane of this invention is used for oral soft tissue augmentation, such as widening of keratinized gingiva and alveolar ridge soft tissue augmentation, and has advantages such as no donor site damage, high biosafety, and ease of operation.

The utility model relates to tissue forceps for assisting in trimming oral soft tissues. The tissue forceps comprise two tissue forceps bodies, each tissue forceps body comprises two forceps bodies, and the two forceps bodies are connected through a forceps shaft to form a forceps type structure capable of being opened and closed around the forceps shaft. Each plier body comprises a plier ring, a plier handle, a plier head and a square clamping plate, the plier ring is connected with the lower end of the plier handle, the plier head is connected with the upper end of the plier handle, and the square clamping plate is arranged on the plier head; a first preset angle is formed between the square clamping plate in one tissue forceps body and the corresponding forceps head, and the square clamping plate is used for clamping soft tissue in an oral cavity anterior tooth area; a second preset angle is formed between the square clamping plate in the other tissue forceps body and the corresponding forceps head, and the square clamping plate is used for clamping soft tissue in the rear tooth area of the oral cavity. More tissues are clamped through the two square clamping plates which are oppositely arranged, so that the tissues are stably clamped and fixed and do not slip off, and subsequent tissue trimming by a blade is facilitated.

The present invention relates to a tooth-whitening catalytic material based on a photothermal integrated Fenton reaction, as well as its preparation method and application. The present invention utilizes an iron-doped carbon aerogel with a large specific surface area, high conductivity, and strong adsorption as a substrate, and modified TiO2 nanoparticles as the primary component of the tooth-whitening product. Laser light of a specific wavelength excites the material's photothermal Fenton effect, releasing a large amount of active substances, thereby degrading tooth surface pigments and achieving the purpose of tooth whitening. Compared with existing technologies, the present invention has the advantage of reducing the adverse effects of high-concentration hydrogen peroxide while not damaging normal oral soft tissue, achieving efficient and safe bleaching results in a short period of time.

This invention relates to a gradient elastic modulus sports protective brace, its preparation method, and its application. The gradient elastic modulus sports protective brace includes at least an impact-resistant layer, a buffer layer, and an adhesive layer with a segmented or continuous gradient distribution of elastic modulus. The adhesive layer is used to adhere to the tooth surface and oral soft tissues, and to help disperse residual impact energy. The buffer layer surrounds the adhesive layer and is used to disperse impact energy. The impact-resistant layer surrounds the buffer layer and is used to resist external impact loads and guide energy inward. The elastic modulus of the impact-resistant layer is greater than that of the buffer layer, and the elastic modulus of the buffer layer is greater than that of the adhesive layer. Compared with existing technologies, this invention, through its gradient elastic modulus distribution design, achieves progressive absorption and effective dissipation of impact energy by the sports brace, significantly reducing the peak force on the user's teeth and periodontal tissues during impact, thereby improving overall protective performance and making it suitable for sports scenarios of varying intensities.

The application provides a tooth bleaching material based on a biological heterojunction and a preparation method and application thereof, and belongs to the field of medical new materials. The tooth bleaching material is a BaTiO3@CeO2-GOx (BCG) biological heterojunction, and the preparation method comprises the following steps: preparing a BaTiO3@CeO2 heterojunction; fixing glucose oxidase GOx on the surface of the BaTiO3@CeO2 heterojunction through electrostatic adsorption to obtain a BaTiO3@CeO2-GOx (BCG) biological heterojunction material. Under the action of ultrasonic waves, the BCG produces active oxygen (ROS) through piezoelectric catalysis, realizes efficient oxidative decomposition of tooth pigments, and simultaneously, the CeO2 component in the BCG can effectively remove excessive free ROS, thereby protecting oral soft tissues from oxidative damage. The material has excellent non-damaging tooth whitening ability in in-vitro experiments, and provides a safe and efficient precise treatment method for oral aesthetic care.

According to the chewing-resistant cow leather collagen pet chew and the preparation method thereof, the palatability of the product is improved through the minced meat flavor coating, and the chewing interest of pet dogs can be attracted. Fiber recombination in the forming process effectively eliminates sharp edges and corners, and the risk of oral soft tissue injury is reduced. The raw material cost is remarkably reduced through recycling of the broken cow leather, and the production economic benefits are improved. Moreover, the plasticity is high after the raw materials are mixed, the chew can be made into a special shape, and the interestingness of interaction between an owner and a pet is increased.

The invention relates to a tool for obtaining free soft tissue flaps in oral soft tissue transplantation surgery, which comprises a handle and a working structure fixed at the front end of the handle, the working structure is made of medical-grade metal materials, and the whole working structure is of an arc shovel-shaped structure and is matched with the radian of an alveolar bone; a working blade is arranged at the front end of the working structure, a depth limiting structure used for limiting the shoveling depth is arranged on the side portion of the working structure, the position of the depth limiting structure is relatively higher than the working blade, and a preset height difference exists between the depth limiting structure and the working blade. The tool ensures that the thickness of the soft tissue valve obtained every time is accurate and uniform through the working head with the standardized thickness and width, obtaining can be completed through one-time cutting and propelling, and the operation efficiency is improved.

The invention discloses a lycium barbarum polysaccharide spray as well as a preparation method and application thereof, and belongs to the technical field of biological medicines. The lycium barbarum polysaccharide spray comprises a partially oxidized dialdehyde polysaccharide aqueous solution and lycium barbarum polysaccharide-gelatin microspheres dispersed in the partially oxidized dialdehyde polysaccharide aqueous solution, the lycium barbarum polysaccharide-gelatin microspheres take cross-linked gelatin as a matrix, and lycium barbarum polysaccharide is uniformly embedded in the cross-linked gelatin. The preparation method of the lycium barbarum polysaccharide spray comprises the following steps: preparing lycium barbarum polysaccharide-gelatin microspheres by adopting an emulsion template method, and dispersing the lycium barbarum polysaccharide-gelatin microspheres in a partially oxidized dialdehyde polysaccharide solution, thereby obtaining the lycium barbarum polysaccharide spray. The invention also discloses an application of the lycium barbarum polysaccharide spray in preparation of a medicine for preventing or / and oral cavity tissue injury. The traditional Chinese medicine active ingredient lycium barbarum polysaccharide is applied to the field of oral medicine through a modern medicine technology, and a brand new scheme with remarkable clinical value is provided for preventing and treating oral soft tissue injury, particularly tobacco-caused injury.