The invention relates to a fast charging cable for a new energy electric vehicle charging pile. The invention belongs to the technical field of wires and cables. The fast charging cable includes two main power line cores, a protective ground line core, a control cable core, a monitoring cable core, filling, an inner layer, a total shielding layer, and a sheath layer. The main power line core and the protective ground line core are formed by conductors, cladding layers and insulating layers. The control cable core is formed by conductors, an insulation layer, filling, a sub-shielding layer, and a cable core protective layer. The monitoring cable core is formed by conductors, an insulation layer, filling, a sub-shield layer, and a cable core sheath layer. An inner protective layer is arranged outside the main power line core, the protective ground line core, the control cable core and the monitoring cable core. A total shielding layer is arranged outside the inner protective layer. A sheath layer is extruded outside the total shielding layer. The fast charging cable has the advantages of high voltage level, good flexibility, good tensile resistance, excellent flame retardancy, weatherability, chemical resistance and electromagnetic interference resistance.