30results about How to "Avoid postoperative complications" patented technology

The invention discloses an injectable temperature-sensitive hydrogel artificial lens material having a cell membrane biomimetic property and a preparation method thereof, and belongs to the field of biomedical materials. The material is prepared through free radical polymerization of polymerizable monomers and an initiator, wherein the polymerizable monomers are divided into three classes; the first class comprises N-isopropylacrylamide, vinyl pyrrolidone, 2-(Dimethylamino)ethyl methacrylate or other temperature-sensitive functional monomers; the second class comprises 2-phenoxyethyl methacrylate or 2-phenoxyethyl acrylate; the third class comprises 2-methylacryloyloxyethyl phosphorylcholine; and the initiator is azodiisobutyronitrile. The material is temperature-sensitive and has favorable water solubility and flowability at low temperature, thereby being beneficial to injection operation; the material can be gelated within the temperature range of a human body, and has favorable mechanical and optical properties; and the artificial lens has the characteristic of cell membrane biomimetic property, has favorable biocompatibility and can reduce the proliferation of human epithelial cells on the surface of the artificial lens, so that surgical incisions are effectively decreased through an injection means.

The invention provides a Chinese medicinal composition for promoting mature of internal arteriovenous fistula and reducing complications, an application and a using method thereof. The Chinese medicinal composition comprises a component A and a component B, wherein the component A is composed of rheum officinale, mirabilite, borneol and paris polyphylla, and the component B is composed of ligusticum wallichii, Chinese angelica, borneol and leech. The Chinese medicinal composition is prepared by adopting the following steps: baking and crushing the component A, and screening through a 100-mesh screen; gradually adding water, and stirring to obtain a paste medicament; immersing the component B with water, decocting for three times, and filtering the filtrates of three times and concentrating to obtain an ointment medicament, wherein an interval is not needed in each time of decoction. The paste medicament is applied to the hand back each time before sleep, and is washed after wakeup in the morning three days before an operation; 2ml of the ointment medicament is applied to the affected part one time a day after suture is taken out after 7-10 days of the operation; 14 days is taken as a course of treatment, and 1-2 courses are used. The Chinese medicinal composition is convenient to obtain materials and easy to manufacture, is convenient to use, economical and practical, has the advantages of low cost, no toxicity or hazard, remarkable use effect and the like, and is mainly used for a patient who is subjected to uremia arteriovenous fistula plasty. The Chinese medicinal composition avoids the adverse response caused by internal administration, and plays an active and effective effect in the process of treating chronic renal failure.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine for haemorrhoids and a preparation method thereof. The traditional Chinese medicine for haemorrhoids is prepared from the following medicinal raw materials in parts by weight: 24-36 parts of fortune paulownia flower, 3-9 parts of garden burnet, 8-16 parts of dicliptera chinensis, 8-16 parts of herba violae, 8-16 parts of dandelion, 8-16 parts of Chinese angelica, 3-9 parts of mirabilite, 3-9 parts of alumen, 8-16 parts of Chinese knotweed herb, 8-16 parts of sophora flower, 8-16 parts of honeysuckle, 8-16 parts of pepper, 8-16 parts of oriental wormwood and 8-16 parts of folium artemisiae argyi. The traditional Chinese medicine for haemorrhoids has the effects of clearing away heat, drying dampness, removing toxicity for detumescence, promoting blood circulation to arrest pain and cooling blood for hemostasis. Clinical test results prove that the total effective rate of the traditional Chinese medicine reaches 96.49%.

The invention relates to a fluorescent probe for targeted marking eye lens epithelial cells and a preparation method and application thereof and belongs to the field of fluorescent sensing materials. The fluorescent probe is DPPHP-2CHO, has functions of in-situ targeted marking of the eye lens epithelial cells and inhibiting of lens epithelial cell proliferation and is suitable for the field of treating cataract. The preparation method includes: adding 1, 4-bis(4-bromophenyl)-2, 5-diphenyl-1, 4-dihydropyroole[3, 2-b] pyrrole, 4-formylbenzeneboronic acid and a catalyst into a reaction container; vacuumizing, feeding shielding gas for more than twice, adding a deoxidized solvent I, and allowing backflow reaction; cooling, adding a solvent II for extraction, using anhydrous magnesium sulfate to dry an organic phase obtained by extraction and separation, and spin-drying the organic phase to obtain a crude product; subjecting the crude product to column chromatography separation and purification, and drying to obtain solid powder which is the fluorescent probe.

The present application relates to a tissue sealant powder, a preparation process thereof, and a tissue sealant. The sealant powder includes a first component and a second component, and the first component is an electrophilic raw material, which itself contains an electrophilic functional group , or a compound with an electrophilic functional group supported by physical means; the second component is a plant-derived biological material; the component distribution ratio is as follows: the mass ratio of the first component: the second component is 1:1-10. The preparation method uses a physical melting method and a fluidized bed method to make the super absorbent substances of the first and second components contain active functional groups without any other catalysts, reagents, or change their own chemical properties. The tissue sealant has rapid liquid absorption, high liquid absorption ability, strong adhesion ability, in vivo degradation, mild inflammatory reaction, and can be directly applied to the wound surface.

The present invention relates to a negative Poisson's ratio myocardial patch with conductive stability and a preparation method thereof. The surface is coated with a conductive coating to obtain a negative Poisson's ratio structure myocardial patch with conductive stability; or, the yarn is first processed to make a conductive coated yarn, and then the conductive coated yarn is used as a raw material for weaving or Knitting and weaving a negative Poisson's ratio structure myocardial patch with concave polygon as the minimum structural unit; the resistance change rate of the prepared myocardial patch is less than 5% under 50% tensile deformation, and the minimum structure The stretch rate of the unit is within 50%, the fabric exhibits a negative Poisson's ratio structure, and expands in the vertical direction of the tensile load, the fabric exhibits a negative Poisson's ratio effect and anisotropy of Young's modulus, which is similar to that of normal myocardial tissue Mechanical behavior matches.

The invention relates to a composite tendon repair material, characterized in that the composite tendon repair material includes a base layer and at least one active unit; the base layer and the at least one active unit are fixed to each other; the base layer includes an extracellular matrix material ; Each active unit in the at least one active unit comprises a first active layer, a second active layer and a cover layer respectively; the first active layer comprises an extracellular matrix material and a first active component; the second active The layer comprises an extracellular matrix material and a second active ingredient; each active unit is prepared by mechanical compression. The repair material promotes the growth and repair of bone tissue wound and the growth and repair of tendon tissue wound at the tear of tendon and bone respectively, and finally promotes the healing of the junction of tendon and bone, effectively forming a transition from bone, calcified cartilage, fibrocartilage to Insertion-like structure of the tendon. This construct will enable the repair of giant rotator cuff tendon tears.

The present invention relates to a production equipment of hemostatic sponge for operation, which comprises a shunt device and a forming device; the shunt device includes a shunt box, an adjustment sheet, a sub-section, and a connecting piece; the shunt box is a triangular box-shaped object, the lower surface is closed, and the upper surface is Need to decide whether it is closed, the apex of the triangle is connected to the pipe, and the bottom plate of the triangle is provided with side-by-side holes, which are used to insert the mold holder. Low; the hemostatic sponge production equipment disclosed in the present invention can realize the production of a one-button fully automated hemostatic stick, which is safe and worry-free to use. Different shapes of hemostatic sticks can be made to meet the hemostatic needs of different parts. It has the effects of rapid hemostasis, prevention of adhesion, acceleration of wound healing, etc., and reduces the prevention of postoperative complications.

The invention discloses a method for making a fully autologous tissue double-coated conformable breast prosthesis. According to the pre-estimated resection range and volume, the skin epidermis and dermis tissue, as well as subcutaneous fat tissue are obtained from the patient's own body, and then The epidermis and skin-removed adipose tissue are placed in a sterile container, placed in a water bath box at 50-60 degrees Celsius for 20-40 minutes to inactivate, and the inactivated autologous adipose tissue is trimmed and sewn into a desired shape and size. Conformal breast prosthesis content, according to the shape and size of the conformal breast prosthesis content, the inactivated skin surface tissue is sewn into the inner capsule of the conformal breast prosthesis content, and the dermis is sewn The outer capsule that forms the conformal breast implant contents. The method of the present invention can prevent the infiltration of inflammatory cells in the surrounding tissue after the prosthesis is implanted, prevent the possible inflammatory reaction of the prosthesis content, have no risk of prosthesis stabbing and rupture, and improve the toughness, elasticity, Shape maintenance and anti-extrusion ability.

According to one aspect of the invention, composite implants for soft tissue repair are provided which comprise (a) a substantially two-dimensional piece of biologic matrix material and (b) one or more non-absorbable synthetic polymeric filaments.