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Compound nucleotide oral liquor for improving immunity and its preparing method

The technology of nucleotide oral liquid and oral liquid is applied in the fields of health care products, compound nucleotide oral liquid and preparation thereof, which can solve the problems of not having two-way regulation of the number of human leukocytes and the inability to reduce the number of leukocytes to a normal level, etc. The effect of enhancing human immunity, growing and repairing intestines, and enhancing appetite

Inactive Publication Date: 2009-03-11
庄田 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Existing nucleotide products cannot reduce the excessively high white blood cell count in the human body to a normal level, and do not have the function of bidirectionally regulating the white blood cell count in the human body

Method used

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Examples

Experimental program
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Effect test

Embodiment 1

[0022] Example 1 Extraction and separation of nucleotides

[0023] 1. Nucleotide extraction: Fermentation biological yeast is the raw material for extracting nucleic acid, and nucleotide (RNA) is extracted from yeast. Put yeast powder (purchased from Hubei Yichang Angel Yeast Co., Ltd., trade name "yeast powder", specification: food-grade biological yeast) into saturated brine with a concentration of 8-10%, heat to 90-95°C, and stir to react After 3-5 hours, cool to 10-15°C, filter to obtain a mixed crude nucleotide solution, adjust to pH 2.5 with 6N hydrochloric acid to acidify and precipitate for 4 hours, purify with ethanol and filter to obtain nucleic acid sludge, and then precipitate with ethanol , temperature at 95°C, 24 hours, adjust pH3, cool down to 20°C and precipitate for 24 hours, purify with dimethoxyethanol, temperature is 95°C, adjust pH3, recover dimethoxyethanol, measure 5'- after 12 hours Nucleotide content above 80% is completed.

[0024] 2. Separation of ...

Embodiment 2

[0026] Embodiment 2 Preparation of nucleotide oral liquid of the present invention

[0027] According to 10,000 bottles, the nucleotides prepared in Example 1 were weighed: 71g of adenine nucleotides, 45g of guanine nucleotides, 62g of uracil nucleotides, 49g of cytosine nucleotides and thymine nucleotides. glycoside 23g; add sterile ionized water, mix evenly, make up to 100 liters, pack 10 ml per bottle into 10,000 bottles, and sterilize.

Embodiment 3

[0028] Embodiment 3 Preparation of nucleotide oral liquid of the present invention

[0029] According to 10,000 bottles, the nucleotides prepared in Example 1 were weighed: 68g of adenine nucleotides, 43g of guanine nucleotides, 50g of uracil nucleotides, 42g of cytosine nucleotides and thymidine nucleotides. glycoside 22g; add sterilized ionized water, mix evenly, set the volume to 100 liters, pack 10 ml per bottle into 10,000 bottles, and sterilize.

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PUM

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Abstract

The invention discloses a new oral liquid of compound nucleotide and preparation thereof. Each ml. of said compound nucleotide oral liquid comprising the following nucleotide in weight: adenylic acid 0.68-0.76mg, guanylic acid 0.43-0.52mg, uridylate 0.5-0.67mg, cytidylic acid 0.42-0.55mg and thymidylic acid 0.22-0.25mg.

Description

technical field [0001] The invention relates to a health care product, in particular to a compound nucleotide oral liquid capable of bidirectionally regulating the number of human leukocytes and improving human immunity and a preparation method thereof, belonging to the field of biotechnology. Background technique [0002] In 1868, Swiss biologist Michel isolated a new phosphorus-containing acidic substance in human cells in the cell laboratory of Dupin University in France, and named it "nuclide". Afterwards, Atman, a scientist in the same laboratory, separated the protein-free substance, which was acidic, and renamed it nucleic acid. This is the earliest nucleic acid discovered in the world. Due to the importance of nucleic acid to life sciences, research on nucleic acid So far, more than 80 biologists, chemists, medical scientists, and physiologists have won Nobel Prizes. The DNA (deoxyribonucleic acid) double helix structure published in the world-renowned "Genetics" ma...

Claims

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Application Information

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IPC IPC(8): A61K31/7076A61K9/08A61K9/10A61P37/04
Inventor 庄田许振亚
Owner 庄田
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