Inspection method for Chinese medicinal composition for treating blood and qi depletion,irregular menstruation

A technology for irregular menstruation and quality detection method is applied in the field of traditional Chinese medicine compositions for treating chronic illness and physical deficiency and women with blood deficiency and qi deficiency and irregular menstruation. The effect of nourishing blood

Inactive Publication Date: 2009-06-24
李湛明 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Hypomenorrhea and amenorrhea are the most common diseases of women. Modern medical treatment lacks effective treatment methods. Traditional Chinese medicine has obvious advantages in treating this disease.

Method used

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  • Inspection method for Chinese medicinal composition for treating blood and qi depletion,irregular menstruation
  • Inspection method for Chinese medicinal composition for treating blood and qi depletion,irregular menstruation
  • Inspection method for Chinese medicinal composition for treating blood and qi depletion,irregular menstruation

Examples

Experimental program
Comparison scheme
Effect test

experiment example 1

[0023] After 150 clinical cases and 50 cases of Fukangbao oral liquid (donkey-hide gelatin, mugwort leaves, white peony root, chuanxiong, angelica, rehmannia glutinosa, licorice) were compared and observed, the report is as follows:

[0024] 1. Clinical data

[0025] The 150 cases in the treatment group were all outpatient cases, 4 cases were over 40 years old, 81 cases were 21-39 years old, 65 cases were 18-20 years old, 21 cases were 4 months old, 99 cases were 5-10 months old , 30 cases over 10 months. The 50 cases in the control group were all outpatient cases, 2 cases were over 40 years old, 30 cases were 21-39 years old, 18 cases were 18-20 years old; 7 cases were 4 months old, 30 cases were 5-10 months old , 13 cases over 10 months.

[0026] 2. Diagnostic criteria of traditional Chinese medicine: according to the "Guiding Principles of Clinical Research of New Chinese Medicines for Amenorrhea" promulgated by the Ministry of Health

[0027] (1) Diagnosis of amenorrhea...

experiment example 2

[0047] Experimental example 2 Research on Quality Control Methods

[0048] [Content Determination] is the determination method of Radix Astragali.

[0049] (1) Instruments and reagents

[0050] 1. Instruments: CS-9301PC thin-layer scanner (Shimadzu, Japan); quantitative capillary (Drummond); MettlerAE100, 200 electronic balance.

[0051] 2. Test drug: Amenorrhea No. 3 oral liquid (composition oral liquid preparation of the present invention) (produced and provided by Guangdong Yongkang Pharmaceutical Co., Ltd.; batch numbers: 020401, 020402, 020403); astragaloside IV reference substance (781-9002, China Provided by the Institute for the Control of Pharmaceutical and Biological Products); D 101 type macroporous adsorption resin (Tianjin Rubber Factory); neutral alumina for chromatography (batch number: 200321 Chemical Reagent Glass Instrument Wholesale Department of Guangzhou Pharmaceutical Company); thin-layer chromatography silica gel G (type 60) (batch number: 990313 Ch...

Embodiment 1

[0085] Example 1 oral liquid

[0086] Ejiao 216g Astragalus 180g Codonopsis 180g

[0087] Rehmannia glutinosa 120g Atractylodes macrocephala 90g Angelica 60g

[0088]For the above six flavors, take Chinese Angelica and Atractylodes Rhizoma Atractylodes Rhizome and cut them into pieces, distill them, collect the distillate for later use, decoct the residue with Astragalus, Codonopsis, Rehmannia glutinosa and water for 3 times, 1.5 hours for the first time, 1 hour for the second and third times, and combine the decoctions , filtered, and the filtrate was concentrated to a clear paste with a relative density of 1.08-1.10 (75°C-80°C). After cooling, ethanol was added to make the alcohol content 50-55%. Stir well, cool, stand still, filter, recover ethanol from the filtrate, concentrate to a relative density of 1.08, and set aside; take donkey-hide gelatin and add appropriate amount of water to melt, filter, and combine the filtrate with the above concentrate; make syrup with ...

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Abstract

The invention discloses a traditional Chinese medicine composition for treating "chronic illness and physical deficiency and irregular menstruation due to blood deficiency and qi deficiency in women" and a preparation method thereof. The composition is composed of donkey-hide gelatin, astragalus root, Codonopsis pilosula, Rehmannia glutinosa, Atractylodes Rhizoma and Angelica sinensis. The traditional Chinese medicine composition can be prepared into dosage forms including oral liquid preparation, tablet, capsule, syrup, dripping pill, pill (concentrated pill), injection and the like by decocting, distilling, concentrating, and adding auxiliary materials; meanwhile, the present invention also provides The quality control method of the composition identification and content determination is presented. The composition preparation of the invention has good effects of nourishing yin and blood, strengthening the spleen and nourishing qi, regulating menstruation and nourishing blood, and has no side effects.

Description

field of invention [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating long-term physical deficiency and irregular menstruation in women with blood deficiency, Qi deficiency, and a preparation method of the composition. Background technique [0002] Hypomenorrhea and amenorrhea are the most common diseases among women. Modern medical treatment lacks effective treatment methods. Traditional Chinese medicine has obvious advantages in treating this disease. [0003] The discharge of menstrual blood is significantly reduced, even dripping, or the menstrual time is too short, less than two days, and the menstrual flow is also reduced. It is recorded in "On the Causes and Symptoms of Various Diseases" that "the moon is less...it is less", and "Danxi Xinfa" is also known as "the classics are few". Women who are over 18 years old and have not menstruated, or who have had menstruation bu...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/481A61K125/00A61K36/344A61K36/804A61K36/284A61K36/232A61K35/36A61P1/14A61P15/00G01N30/90
Inventor 李湛明
Owner 李湛明
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