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Method for producing hollow capsules dissoluble in stomach by using seaweed polysaccharide as raw material

A technology of seaweed polysaccharides and hollow capsules, applied in capsule delivery, chemical instruments and methods, colloid chemistry, etc., can solve the problems of harming human beings, and achieve the effects of low cost, less mold and deterioration, and no toxic and side effects

Inactive Publication Date: 2009-08-26
黄族和
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The hollow capsule of prior art adopts gelatin to make usually, and gelatin then is boiled out by the skin, bone, tendon of animals such as pig, ox, and in recent years infectious diseases such as pig, ox once occurred in countries all over the world, endanger human beings, use The gelatin made from the skin, bone, and tendon of these animals is used to make medicinal capsules, which will be restricted and eliminated in the future

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Embodiment 1, a kind of seaweed polysaccharide gum of the present invention makes the method for stomach-dissolving hollow capsule, is used for making stomach-dissolving medicinal empty capsule, and it comprises the following steps;

[0028] The first step, raw material pretreatment: adjust the viscosity of the raw material powder, namely seaweed polysaccharide gum, to 5-30 centipoise, the fineness to 60-200 mesh, and the pH value to 5.0-7.0;

[0029] The second step, sol: In a stainless steel container, pour 6 to 10 times the weight of seaweed polysaccharide glue into pure water, gradually sprinkle the glue powder in, and sprinkle the powder while stirring until it is completely dissolved; when the production batch is relatively large, A mixer can be used for mixing;

[0030] The third step, blending: add no more than 1 / 10,000 natural pigments and titanium dioxide to the material glue to make corresponding colors;

[0031] The fourth step, grinding: use a three-roller...

Embodiment 2

[0046] Embodiment 2, a kind of seaweed polysaccharide gum of the present invention makes the method for gastro-soluble empty capsule, is used for making enteric-coated medicinal empty capsule, and it comprises the following steps;

[0047] The first step, raw material pretreatment: adjust the viscosity of the raw material powder, namely seaweed polysaccharide gum, to 5-30 centipoise, the fineness to 60-200 mesh, and the pH value to 5.0-7.0;

[0048]The second step, sol: In a stainless steel container, pour 6 to 10 times the weight of seaweed polysaccharide glue into pure water, gradually sprinkle the glue powder in, and sprinkle the powder while stirring until it is completely dissolved; when the production batch is relatively large, A mixer can be used for mixing;

[0049] The third step, blending: add no more than 1 / 10,000 natural pigments and titanium dioxide to the material glue to make corresponding colors;

[0050] The fourth step, grinding: use a three-roller or multi-...

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Abstract

A process for preparing the gastro-soluble hollow capsule from polymycose gum includes such steps as pre-treating, fusing, mixing with additives, grinding, thermal fusing, dipping, cooling, baking, rewetting, demoulding, cutting, examining, baking, sleeving and packing.

Description

technical field [0001] The invention relates to a method for making a hollow capsule, in particular to a method for making a gastric-soluble hollow capsule from seaweed polysaccharide. Background technique [0002] Empty capsule is a kind of drug carrier, which can be used to fill various powdery and granular drugs, especially for powdery and granular drugs with bitter, astringent or irritating taste, after filling with hollow capsules, the bad taste and smell of the drug will be eliminated. Covering, people will not have bad feeling when swallowing the capsule medicament, after the capsule medicament is swallowed by people, it can disintegrate in people's stomach or intestines, release medicine, and achieve the purpose of drug treatment. There are usually two types of hollow capsules. One is stomach-soluble hollow capsules. After the medicines in gastric-soluble hollow capsules enter the stomach of the human body, the capsules disintegrate, the medicines in the capsules are...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61J3/07B01J13/00
Inventor 黄族和
Owner 黄族和