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Prepn process of superfine Chinese medicine powder prepn for treating rheumatic disease

A technology of traditional Chinese medicine preparation and ultrafine powder, which is applied in the field of medicine, can solve the problems that affect the onset time and curative effect of drugs, and can only be thrown away in vain, and achieve the effects of low cost, improved product quality, and enhanced stability

Active Publication Date: 2009-08-26
JILIN CHANGBAISHAN PHARMA GROUP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Shexiang Fengshi Capsule has the functions of expelling wind and dampness, activating collaterals and relieving pain. It is a commonly used traditional Chinese medicine for clinical treatment of rheumatism. The prescription contains a large amount of animal medicine and medicinal materials with strong toughness and fiber. The traditional preparation process can only crush it to 100 It is difficult to crush it finer, only a few cell walls are broken, and the active ingredients in the cells need to go through several or even dozens of cells before they can enter the solvent and be absorbed by the human body, and a considerable part of the active ingredients cannot Through the cell wall and into the solvent, this part can only be thrown away, seriously affecting the onset time and curative effect of the drug

Method used

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  • Prepn process of superfine Chinese medicine powder prepn for treating rheumatic disease
  • Prepn process of superfine Chinese medicine powder prepn for treating rheumatic disease

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Take 15g of Chuanwu, 10g of scorpion, 25g of earthworm (washed in wine), 25g of black soybean (fried), 30g of honeycomb (washed in wine), 0.5g of musk, and 200g of black snake (removed in wine) for later use.

[0024] Preparation:

[0025] ① Take Chuanwu, Scorpion, Dilong, black beans (stir-fried), honeycomb (washed in wine), black snake (headed and soaked in wine) and grind them into fine powder, grind musk into fine powder with a mortar, and set aside;

[0026] ② Pulverize the 6-flavor fine powder such as Aconitum aconitum prepared in ① and the musk fine powder into superfine powder, the temperature is 20° C., and the fineness is 200 mesh;

[0027] ③Add 1% micronized silica gel to the superfine powder prepared in ②, mix well, and set aside;

[0028] 4. The medicinal powder in 3. is packed into a capsule, and made into a hard capsule to obtain the present invention.

Embodiment 2

[0030] Take 15g of Chuanwu, 10g of scorpion, 25g of earthworm (washed in wine), 25g of black soybean (fried), 30g of honeycomb (washed in wine), 0.5g of musk, and 200g of black snake (removed in wine) for later use.

[0031] Preparation:

[0032] ① Take Chuanwu, Scorpion, Dilong, black beans (stir-fried), honeycomb (washed in wine), black snake (headed and soaked in wine) and grind them into fine powder, grind musk into fine powder with a mortar, and set aside;

[0033]

[0034] 2. Pulverize the 6-flavor fine powder such as Aconitum aconitum prepared in ① and the musk fine powder into superfine powder, the temperature is 18° C., and the fineness is 300 mesh;

[0035] 3. Add 2% talcum powder to the superfine powder prepared in 2., mix well, and set aside;

[0036] ④ making the medicated powder in ③ into granules, coating with film, and making coated granules to obtain the present invention.

Embodiment 3

[0038] Take 15g of Chuanwu, 10g of scorpion, 25g of earthworm (washed in wine), 25g of black soybean (fried), 30g of honeycomb (washed in wine), 0.5g of musk, and 200g of black snake (removed in wine) for later use.

[0039] Preparation:

[0040] ① Take Chuanwu, Scorpion, Dilong, black beans (stir-fried), honeycomb (washed in wine), black snake (headed and soaked in wine) and grind them into fine powder, grind musk into fine powder with a mortar, and set aside;

[0041] 2. Pulverize the 6-flavored fine powder and musk powder prepared in ① into superfine powder, the temperature is 14 ° C, and the fineness is 400 mesh;

[0042] ③Add 3% micronized silica gel to the superfine powder prepared in ②, mix well, and set aside;

[0043] ④ making the medicinal powder in ③ into honeyed pills to obtain the present invention.

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Abstract

The present invention discloses the preparation process of superfine Chinese medicine powder preparation for treating rheumatic disease. The superfine Chinese medicine powder is prepared with Sichuan aconite root, scorpion, earthworm, black bean, honeycomb, black-tail snake and musk and through superfine crushing to 200-1000 mesh at 20 deg.c and below. The superfine Chinese medicine powder may be prepared into different orally taken preparations, including hard capsule, soft capsule, granule, coated granule, dripping pill, etc. The medicine preparations with small medicine particle size and high cell wall breaking rate has high bioavailability, fast leaching out of the effective components, quick acting and high curative effect.

Description

technical field [0001] The invention belongs to the technical field of medicine, and specifically relates to a preparation method of a traditional Chinese medicine preparation for treating rheumatism, and the international patent classification numbers are A61K35 / 78 and A61P29 / 00. Background technique [0002] Rheumatism is a universally recognized difficult disease. According to the statistics of the World Health Organization, there are 40 million patients who are disabled due to rheumatism every year. In China alone, there are as many as 20 million patients with rheumatism and rheumatoid, and one tenth Is a critically ill patient. The patient suffers from joint pain, and his movements remain unchanged. In severe cases, he cannot take care of himself, which seriously affects his work and life. Rheumatism is an "intractable disease" that is difficult to overcome, and is called "undead cancer" by world medicine. [0003] Shexiang Fengshi Capsule has the functions of expellin...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/714A61K35/64A61K35/55A61K35/58A61K9/20A61K9/48A61P29/00A61K35/62A61K35/646
Inventor 高陆高文功王丽清姜英夫程秀娟付强于艳辉赵源慧姜轲
Owner JILIN CHANGBAISHAN PHARMA GROUP
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