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Medical chitosan dressing and production method thereof

A technology of chitosan and polyvinyl alcohol, applied in medical science, bandages, absorbent pads, etc., can solve the problems of not being able to maintain a moist environment on the wound, not being suitable for dry wounds, and not being able to re-form a film, so as to reduce the work of changing dressings Quantity, low cost, easy to observe and operate

Active Publication Date: 2009-09-16
WUHAN DAZHENG HIGH TECH BIOLOGICAL MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But there are following problems in the chitosan medical dressing of existing development: (1) degree of humidity is not enough, can not keep the moist environment suitable for wound surface, is not suitable for dry wound surface; (3) It cannot be re-formed after the wound dissolves

Method used

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  • Medical chitosan dressing and production method thereof

Examples

Experimental program
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Effect test

Embodiment Construction

[0013] Table 1 is the raw materials and proportioning used in Examples 1 to 4 of the present invention

[0014] Raw materials used in each embodiment of table 1 and proportioning unit: Kg

[0015] Example 1

Example 2

Example 3

Example 4

Chitosan

10

5

8

10

polyvinyl alcohol

12

7

10

12

gelatin

10

6

10

12

Glycerin

20

12

17

22

water

48

25

55

60

[0016] The production method of medical chitosan dressing, carries out as follows: (1) polyvinyl alcohol, gelatin are fully swollen with water by the amount of above-mentioned form, then water bath dissolves; (2) chitosan is dissolved in glycerol aqueous solution, and Mix the two solutions together and stir well, adjust the pH value to 4-7 with acetic acid, filter, defoam, and directly fill to make medical chitosan gel dressing, or flat-plate salivation film to make medical c...

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Abstract

The invention relates to a medical chitosan dressing, which is composed of chitosan, polyvinyl alcohol, gelatin and glycerin. The above-mentioned components are calculated in parts by weight: chitosan: 5-10, polyvinyl alcohol: 6-15, Gelatin: 5-10, glycerin: 10-20, water 45-75, fully swell polyvinyl alcohol and gelatin with water, then dissolve in a water bath, dissolve chitosan in glycerin aqueous solution, mix the two solutions together and stir well , adjust the pH value to 4-7, filter and defoam to obtain a medical chitosan dressing. The invention satisfies the moist requirement of the wound surface, absorbs infiltration without forming effusion with the wound surface, and re-forms a film after the wound surface dissolves, so as to provide an ideal healing environment and platform for the wound surface.

Description

technical field [0001] The invention relates to a medical chitosan dressing and a production method thereof. Background technique [0002] Chitin, also known as chitin and chitin, is the only positively charged natural polymer in nature. Its chemical name is β-1,4-2-acetylamino-2-deoxy-D-glucose, and its molecular formula is (C 8 h 13 NO 5 )n, insoluble in water, dilute acid, dilute alkali and general organic solvents, widely exists in shrimp and crab shells, insect shells. The products of chitin after deacetylation are called chitosan, chitosan, and soluble chitin. Chitosan is soluble in water, has good biocompatibility, does not produce rejection reaction with body fluids, tissues and cells, has low immune antigenicity, is biodegradable in vivo, has no toxic side effects, and has high safety. It has the properties of improving immune activity, antibacterial, promoting tissue healing and repair, hemostasis, and inhibiting scar formation. It is widely used in industry, ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L15/44A61L15/28A61L15/24
Inventor 郭兆刚
Owner WUHAN DAZHENG HIGH TECH BIOLOGICAL MEDICINE
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