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Chinese medicinal composition for dispelling wind and freeing collateral vessels, strengthening muscles and bones, and preparation method thereof

A technology for strengthening tendons and bones, dispelling wind and dredging collaterals, which is applied in drug combination, medical formula, drug delivery, etc. It can solve the problems of poor absorption and bioavailability of Chinese medicine preparations when they are dissolved and released, and poor granule formability.

Active Publication Date: 2009-12-02
SHAANXI HANWANG PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The inventors found that only by pulverizing the above fourteen Chinese herbal medicines into fine powder, the dissolution and release of the prepared Chinese medicine preparation, the absorption and bioavailability of the medicine in the body are not good
And the ethanol solution of polyvinylpyrrolidone was used as a binder in the preparation process, but it was found that the aged cortex in the medicinal material was loose, and the ethanol solution of polyvinylpyrrolidone was used as a binder, and the granules formed by it had poor formability

Method used

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  • Chinese medicinal composition for dispelling wind and freeing collateral vessels, strengthening muscles and bones, and preparation method thereof
  • Chinese medicinal composition for dispelling wind and freeing collateral vessels, strengthening muscles and bones, and preparation method thereof
  • Chinese medicinal composition for dispelling wind and freeing collateral vessels, strengthening muscles and bones, and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0108] [Example 1] Preparation of tablet

[0109] The formula of the Chinese medicine tablet includes the following Chinese medicine raw materials:

[0110] Chuanwu 90g

[0111] Zhicaowu 90g

[0112] Nux 6g

[0113] Pinellia 25g

[0114] Arisa 13g

[0115] Chenpi 10g

[0116] Sichuan Ayurvedic Knuckle 6g

[0117] Papaya 6g

[0118] Codonopsis 10g

[0119] Uncaria 10g

[0120] Dendrobium 6g

[0121] Dipsacus 15.1g

[0122] Chrysanthemum stone 4.5g

[0123] Baicao Cream 4.5g

[0124] Chinese medicine tablet is prepared by following process:

[0125] 1) Process the above-mentioned raw materials of traditional Chinese medicines respectively to obtain decoction pieces or coarse particles of Chinese medicines;

[0126] 2) Grinding the prepared Chinese medicine slices or coarse particles in the above steps to obtain Chinese medicine fine powder;

[0127] 3) Mix the obtained traditional Chinese medicine fine powder, add syrup to make granules, add magnesium stearate and...

Embodiment 2

[0128] [Example 2] Preparation of tablet

[0129] The formula of the Chinese medicine tablet includes the following Chinese medicine raw materials:

[0130] Chuanwu 93g

[0131] Zhicao Wu 93g

[0132] Nux Nux 9g

[0133] Pinellia 32g

[0134] Arisa 16g

[0135] Chenpi 17g

[0136] Sichuan Ayurvedic Knuckle 8g

[0137] Papaya 8g

[0138] Codonopsis 17g

[0139] Uncaria 17g

[0140] Dendrobium 8g

[0141] Dipsacus 15.8g

[0142] Chrysanthemum stone 4.8g

[0143] Baicao Cream 4.8g

[0144] Chinese medicine tablet is prepared by following process:

[0145] 1) Process the above-mentioned raw materials of traditional Chinese medicine to obtain Chinese medicinal decoction pieces or coarse particles, wherein the particle size of the coarse particles is 0.84mm;

[0146] 2) Grinding the decoction pieces or coarse particles of the traditional Chinese medicine prepared in the above steps respectively to obtain fine powder of Chinese medicine, wherein the particle size of the...

Embodiment 3

[0149] [Example 3] Preparation of tablet

[0150] The formula of the Chinese medicine tablet includes the following Chinese medicine raw materials:

[0151] Sichuan Aconitum 91g

[0152] Zhicao Wu 91g

[0153] Nux Nux 7g

[0154] Pinellia 28g

[0155] Arisa 14g

[0156] Chenpi 13g

[0157] Sichuan Ayurvedic Knuckle 7g

[0158] Papaya 7g

[0159] Codonopsis 13g

[0160] Uncaria 13g

[0161] Dendrobium 7g

[0162] Dipsacus 15.2g

[0163] Chrysanthemum stone 4.6g

[0164] Baicao Cream 4.6g

[0165] Chinese medicine tablet is prepared by following process:

[0166] 1) Process the above-mentioned raw materials of traditional Chinese medicine to obtain Chinese herbal decoction pieces or coarse particles, wherein the particle size of the coarse particles is 0.80mm;

[0167] 2) Grinding the decoction pieces or coarse particles of the traditional Chinese medicine processed in the above steps to obtain fine powder of Chinese medicine, wherein the particle size of the fine ...

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Abstract

The invention relates to a traditional Chinese medicine preparation for dispelling wind, dredging collaterals, strengthening tendons and strengthening bones. The preparation formula includes the following traditional Chinese medicine raw materials: 90-95 parts for making Aconitum aconiti, 90-95 parts for making Aconitum aconitum, and 6-10 parts for making Nux. , 25-35 parts of Pinellia, 13-18 parts of Arisa, 10-20 parts of Chenpi, 6-9 parts of Sichuan Achyranthes, 6-9 parts of papaya, 10-20 parts of Codonopsis, 10-20 parts of Uncaria, 6 parts of Dendrobium -9 parts, 15.1-16 parts of Dipsacus, 4.5-4.9 parts of Jinzhengshi, 4.5-4.9 parts of Baicao Cream; prepared by the following process: first process the above raw materials to obtain Chinese herbal medicine pieces or coarse particles, then pulverize and then ultrafine pulverize After mixing, add pharmaceutically acceptable auxiliary materials according to the preparation method of traditional Chinese medicine preparations to prepare various dosage forms suitable for administration. The invention rationally assembles the Chinese medicinal materials, and pulverizes them by adopting ultrafine pulverization technology, thereby improving the bioavailability of the preparation and greatly improving the absorption rate of the Chinese medicinal materials.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for dispelling wind and dredging collaterals, strengthening tendons and strengthening bones and a preparation method thereof, especially the role of the traditional Chinese medicine composition in preparing medicines for treating rheumatoid arthritis, rheumatoid arthritis and osteoporosis application. Background technique [0002] The total number of patients with joint diseases in my country has exceeded 100 million. According to reports, the prevalence of arthritis in my country is extremely high, and it is more common in the elderly. Statistics show that 50% of people over the age of 50 suffer from arthritis, and people over the age of 65 suffer from this disease. Diseased women and men up to more than 80%. The prevalence rate of rheumatoid arthritis in my country is about 0.35%, but it can easily cause disability in patients. The rate of osteoclastosis in the course of two years is...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8984A61K36/8888A61K36/8884A61K36/752A61K36/74A61K36/732A61K36/714A61K36/56A61K36/344A61K36/21A61K36/185A61K36/00A61K33/06A61K9/00A61K9/28A61P19/02A61P29/00
Inventor 田惠玲王政军赵斌刘平许惠芳王娟郭晓林杜浩宇白彦明侯建文
Owner SHAANXI HANWANG PHARM CO LTD