Preparation method for thin coating medicine for treating cold

A film-coated tablet and Guanzhong technology, which is applied in the field of preparation of traditional Chinese medicine and western medicine composition, can solve the problems of being unable to meet the needs of different clinical conditions and the market, not giving full play to the excellent curative effect, and having no standard quality. Cost and energy consumption are reasonable and optimized, product dosage forms are enriched, and quality is controllable

Inactive Publication Date: 2009-12-09
ZHEJIANG WECOME MEDICINE IND
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But it has the following disadvantages: at present, there is only one dosage form of Suganning Capsules on the market, which cannot meet the needs of different clinical conditions and the needs of the market. Therefore, the above-mentioned excellent curative effect of this drug has not been fully utilized, which is very unfavorable to the majority of patients.
Moreover, the preparation of general Chinese medicine tablets has problems such as complicated process, no quality standard, difficult quality control, and high cost.

Method used

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  • Preparation method for thin coating medicine for treating cold
  • Preparation method for thin coating medicine for treating cold
  • Preparation method for thin coating medicine for treating cold

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Guanzhong 320g Bupleurum 320g Daqingye 240g Honeysuckle 160g Bezoar 8g

[0030] Acetaminophen 100g Chlorpheniramine Maleate 1.2g Microcrystalline Cellulose 50g

[0031] Carboxymethyl Starch Sodium 60g Magnesium Stearate 10g

[0032] Its preparation method comprises the following steps:

[0033] 1) Take Guanzhong, Bupleurum, Daqingye, and honeysuckle, add water and decoct twice, add 10 times the amount of water for the first time, decoct for 3 hours, add 8 times the amount of water for the second time, decoct for 2 hours, use 300 Filter through a mesh filter cloth, and combine the filtrates;

[0034] 2) Concentrate the filtrate into a clear paste with a relative density of 1.20-1.25 (50-60°C) at a temperature of 70-80°C and a vacuum of 0.08-0.1Mpa. Dry under the condition of 0.08~0.1Mpa, crush into fine powder, add bezoar powder, acetaminophen, chlorpheniramine maleate, microcrystalline cellulose, sodium carboxymethyl starch and mix well;

[0035]3) Granulate with 70...

Embodiment 2

[0040] Guanzhong 320g Bupleurum 320g Daqingye 240g Honeysuckle 160g Artificial Bezoar 8g

[0041] Acetaminophen 100g Chlorpheniramine Maleate 1.2g Dextrin 50g

[0042] Pregelatinized starch 60g Magnesium stearate 10g

[0043] Its preparation method comprises the following steps:

[0044] 1) Take Guanzhong, Bupleurum, Daqingye, and honeysuckle, add water and decoct twice, add 8 times the amount of water for the first time, decoct for 2 hours, add 6 times the amount of water for the second time, decoct for 1 hour, use 200 Filter through a mesh filter cloth, and combine the filtrates;

[0045] 2) Concentrate the filtrate into a clear paste with a relative density of 1.20-1.25 (50-60°C) at a temperature of 70-80°C and a vacuum of 0.08-0.1Mpa. Dry under the condition of 0.08~0.1Mpa, crush into fine powder, add artificial bezoar powder, acetaminophen, chlorpheniramine maleate, dextrin, and pregelatinized starch and mix well;

[0046] 3) Granulate with 70% ethanol, dry at a tempe...

Embodiment 3

[0051] Guanzhong 320g Bupleurum 320g Daqingye 240g Honeysuckle 160g Artificial Bezoar 8g

[0052] Acetaminophen 100g Chlorpheniramine Maleate 1.2g Microcrystalline Cellulose 40g

[0053] Starch 50g Magnesium stearate 12g

[0054] Its preparation method comprises the following steps:

[0055] 1) Take Guanzhong, Bupleurum, Daqingye, and honeysuckle, add water and decoct twice, add 12 times the amount of water for the first time, decoct for 3 hours, add 10 times the amount of water for the second time, decoct for 2 hours, use 300 Filter through a mesh filter cloth, and combine the filtrates;

[0056] 2) Concentrate the filtrate into a clear paste with a relative density of 1.20-1.25 (50-60°C) at a temperature of 70-80°C and a vacuum of 0.08-0.1Mpa. Dry under the condition of 0.08-0.1Mpa, crush into fine powder, add bezoar powder, acetaminophen, chlorpheniramine maleate, microcrystalline cellulose, and starch and mix well;

[0057] 3) Granulate with 70% ethanol, dry at a tempe...

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Abstract

A Chinese medicine in the form of coated tablet for treating cold is prepared from paracetamol, chlorphenamine maleate, and 5 Chinese-medicinal materials including isatis leaf, honeysuckle flower, bupleurum root, etc. Its preparing process is also disclosed.

Description

(1) Technical field: [0001] The invention discloses a method for preparing a film-coated tablet for treating colds, which belongs to a method for preparing a combination of traditional Chinese medicine and western medicine. (two) background technology: [0002] Traditional Chinese medicine believes that a cold is caused by wind evils invading the human body through the skin and hair, but wind evils not only invade alone, but also often "attack" with cold, damp, heat or heat together. Thus, it can be divided into different cold syndrome types. At present, the anti-cold medicines on the Chinese market mainly include: Xinkangtek, Kangbid, Gankang, Baijiahei, Ganmaotong, etc. Chinese patent cold medicine, adhering to the fine tradition of Chinese medicine, occupies an important position in my country's pharmaceutical market. In recent years, Chinese patent medicines have made great progress in terms of efficacy stability, dosage forms, convenience of use, and new product devel...

Claims

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Application Information

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IPC IPC(8): A61K9/28A61K36/35A61K36/19A61K36/315A61K36/11A61K35/413A61K31/4402A61K31/167A61P31/00A61P11/00
Inventor 代军平杨帆
Owner ZHEJIANG WECOME MEDICINE IND
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