Preparation method for externally used ophicalcitum compound emergency life saving hemostatic

A stamenite and hemostatic agent technology, applied in the field of preparation of external stamenite compound emergency life-saving hemostatic agent, to achieve good hemostatic effect, rich raw materials, and accelerate the blood coagulation process

Active Publication Date: 2009-12-23
ZHEJIANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

So far, there are no domestic and foreign patent reports on the application of stamens and their compounds in blood coagulation materials, wound treatment and trauma repair, and the combination of natural zeolite with medical bandages and medical adhesives in different forms for trauma repair

Method used

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  • Preparation method for externally used ophicalcitum compound emergency life saving hemostatic
  • Preparation method for externally used ophicalcitum compound emergency life saving hemostatic
  • Preparation method for externally used ophicalcitum compound emergency life saving hemostatic

Examples

Experimental program
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Effect test

Embodiment 1

[0036] Example 1

[0037] A certain amount of stamens is put into a traditional Chinese medicine pulverizer, and the pulverization time is about 5 minutes; the particle size obtained after pulverization is 1 micron to 1 mm. The pulverized stamens were dried in an oven at 100° C. for 1 h. Its hemostatic effect is good. See attached Figure 4 , 5 6.

Embodiment 2

[0039] Take a certain amount of stamens and roast them at 300°C, 500°C, 700°C, and 900°C for 6 hours to obtain heat-treated stamens. Dry the stamen above in an oven at 100°C for 24h. In the range of 100 ~ 500 ℃, stamen's hemostatic effect is good, and its hemostatic effect is shown in the appendix image 3 .

Embodiment 3

[0041] Mix crushed stamen with 1.0mol / L CaCl 2 Mix according to the solid-liquid ratio of 1g / 20m, react at room temperature for 24 hours, wash with deionized water, and dry in an oven at 100°C for 24 hours to obtain modified stamens rich in calcium. The hemostatic effect is significantly better than that of raw stamens. See attached for hemostatic effect Figure 4 .

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Abstract

The present invention provides a preparation method of an external-use ophicalcitum compound emergency hemostat. The present invention grinds the natural ophicalcitum into a certain particle diameter, carries out the calcium chloride modification treatment through different temperature treatments, and obtains the ophicalcitum compound material with high hematopoietic function by mixing with other auxiliary compound materials. The present invention can be used for hemostasis on different medical occasions, can be combined with other medical materials and medical apparatuses, can be made into adhesive bandage, transfusion bandage, self-adhesive dressing, tablet and capsule core material, operation packet, first-aid packet, etc., and can also be made as the oral medicine and be used with other external-use medicines so as to get better curing effect. The present invention has the advantages of simple and feasible operation, abundant materials, low price and easy access, convenient application, good hematopoietic effect and less discharged heat.

Description

technical field [0001] The invention relates to an emergency life-saving hemostatic agent for treating fatal large blood vessel bleeding uncontrollable by conventional hemostatic measures and a preparation process thereof, in particular to a preparation method of an external-use stamen compound emergency life-saving hemostatic agent. Background technique [0002] Emergency life-saving hemostatic agent is an emerging research field in the world. Emergency life-saving hemostats are primarily developed for emergencies where bleeding does not stop in trauma. An emergency like aortic bleeding can be contained within a short period of time (3 minutes), gaining valuable time for further medical treatment. [0003] According to the statistics of the Ministry of Health in 2007, there are about 200 million people with various injuries every year, and about 700,000 to 750,000 deaths due to injuries such as wars, traffic accidents, and major natural disasters. Excessive blood loss is t...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K33/10A61P7/04A61L15/44A61K33/06
Inventor 范杰李云龙
Owner ZHEJIANG UNIV
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