Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Shanxiangyuan leaf extract, preparation method and uses thereof

A technology for the round leaves and extracts of Shanxiang, which is applied in the fields of pharmaceutical formulations, anti-infectives, and drug combinations, etc.

Inactive Publication Date: 2007-08-08
胡军
View PDF1 Cites 26 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the preparations of Shanxiang round leaves on the market include Shanxiangyuan granules, Shanxiangyuan tablets, Shanxiangyuan buccal tablets, etc., which are throat pain drugs. They are clinically used for the treatment of lung and stomach heat, pharyngitis, acute tonsillitis, and sore throat. Good curative effect, so far there are no reports of adverse reactions of safflower and its preparations

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Shanxiangyuan leaf extract, preparation method and uses thereof
  • Shanxiangyuan leaf extract, preparation method and uses thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Embodiment 1: Get the round leaves of Cymbidium chinensis, add water and decoct 2 times, the first time 16 times the amount for 2 hours, the second time 14 times the amount for 1.5 hours, combine the decoction liquid, concentrate under reduced pressure until the relative density is 1.08~1.18 (80 ℃ heat measurement), add ethanol until the alcohol content is 75%, stir, let stand for 24 hours, filter, recover ethanol from the filtrate, concentrate under reduced pressure to 1:0.8~1.6 (W / V), add water to dilute to 3 times the amount of medicinal materials (V / W), dilute hydrochloric acid to adjust the pH value to 4, and slowly pass through (about 1BV / hr) 2 times the amount of medicinal materials (W / W) AB-8 macroporous adsorption resin column that has been treated , water elutes 3BV (about 2BV / hr), 15% ethanol elutes 3BV (about 2BV / hr), 65% ethanol elutes, collects 65% ethanol eluate, reclaims ethanol, concentrates under reduced pressure, and spray-dries to obtain The extract ...

Embodiment 2

[0047] Embodiment 2: With the process of water boiling and alcohol precipitation in Example 1, the extract is obtained, and slowly passes through (about 1BV / hr) 2 times the treated polyamide column of the medicinal material amount (W / W), and water elutes 4BV ( about 2BV / hr), eluted with 95% ethanol, collected the eluate, recovered ethanol, concentrated under reduced pressure, and spray-dried to obtain the extract of Cymbidium rotifera, with a yield of about 3.4%.

Embodiment 3

[0048] Example 3: The same process as in Example 1 was boiled and alcoholized to obtain the extract, the pH value was adjusted to 4 with dilute hydrochloric acid, extracted 4 times with water-saturated n-butanol, the extracts were combined, the n-butanol was recovered under reduced pressure, concentrated, and sprayed Dry it to get it; or mix the n-butanol extraction concentrate with an appropriate amount of diatomaceous earth, dry it in the air, add ethanol to extract twice, combine the ethanol extract, recover ethanol, concentrate under reduced pressure, and spray dry to get it. The yield is 3.6%.

[0049] 1. Determination of total phenolic acid content:

[0050] Determination according to ultraviolet-visible spectrophotometry (Appendix V A of Chinese Pharmacopoeia 2005 edition).

[0051] Preparation of reference substance solution Accurately weigh gallic acid reference substance, add absolute ethanol to make a solution containing 20μg per 1ml, and set aside.

[0052] Prepa...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a method for preparing the suaveolic round leaf extractive which contains celery element or the chromocor compound with celery element as corn, or relative salt. The invention also provides relative quality control method, while said extractive can be used to prepare the drug for treating virus B hepatitis, thrombus, cancer, or the like.

Description

technical field [0001] The present invention relates to an extract of traditional Chinese medicine, in particular to a flavonoid glycoside chemical component containing apigenin or apigenin as an aglycone and a pharmaceutically acceptable salt thereof, and a preparation method of the extract , the quality control method of the extract, and the use of the extract in the preparation of antibacterial, antiviral, antioxidative, antimutagenic, antitumor, antithrombotic, antiarteriosclerotic, liver protective, antihepatitis B virus, antidepressant, neuron protective and immune Regulatory and other drugs, such as the application in the preparation of drugs for the treatment of pharyngitis, oral ulcers, gynecological inflammation, hepatitis, viral colds, tumors, and cardiovascular and cerebrovascular diseases. Background technique [0002] The fresh or dried leaves of Turpinia arguta Seem. or Turpinia indochinensis, a plant of the family Oilaceae, have the effects of clearing away h...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/185A61P31/00A61P9/00A61P1/16A61P25/00A61K31/7048
Inventor 胡军
Owner 胡军
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com