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Patrinai villosa dropping pill and its preparing process

A technology of Paijiang and dripping pills, which is applied in the fields of pill delivery, pharmaceutical formulations, and medical preparations of non-active ingredients, etc. It can solve the problems of uneven dispersion of substances, long dissolution time of dripping pills, and affecting bioavailability, etc. Achieve high bioavailability, avoid the first-pass effect, avoid the effect of stimulating side effects

Active Publication Date: 2010-09-08
云南云河药业股份有限公司
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  • Summary
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AI Technical Summary

Problems solved by technology

[0005] However, due to the physical and chemical characteristics of the Paijiang raw material itself, the Patiotache dripping pills prepared according to the existing dripping pill preparation method have a very uneven material dispersion state, which makes the dissolution time of the dripping pills longer and affects It affects the absorption of the human body and also affects the improvement of bioavailability

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0021] In order to observe the difference in the quality of the Baijiang dripping pills before and after adding chitin, we did the following two groups of experiments respectively:

[0022] Experiment 1: According to parts by weight, Patrador was mixed with polyethylene glycol 2000, or polyethylene glycol 4000, or polyethylene glycol 6000, or polyethylene glycol at a ratio of 1:1, 1:3, and 1:9, respectively. Ethylene glycol 8000, or polyethylene glycol 10000, or polyethylene glycol 20000 are mixed, and prepared according to the steps specified in the preparation method, 6 groups of experiments without adding chitin can be obtained, and 3 groups of different experimental results can be obtained See Table 1-1 to Table 1-3.

[0023] Experiment 2: Using the mixture of polyethylene glycol and chitin as the matrix, the extract of Padina Patraceae was mixed with the matrix in parts by weight at a ratio of 1:1, 1:3, and 1:9 According to the steps specified in the preparation method, ...

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PUM

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Abstract

The invention discloses a Chinese medicinal composition with mind tranquilizing, antitumour, antibiotic, antiviral, liver protecting, and gallbladder smoothing effects, specially relates to an oral preparation prepared from dahurian patrinia as raw material. The invention is to supply the insufficiency of the present technology in preparing dripping pill, to provide a dripping pill of dahurian patrinia with short dissolvation, high bioavailability, and rapid absorption. The inventive dripping pill of dahurian patrinia is added with chitin in the substrate.

Description

technical field [0001] The invention relates to a pharmaceutical composition with sedative, anti-tumor, antibacterial, anti-viral, hepatoprotective and choleretic functions, and in particular to an oral preparation prepared from Patrin. Background technique [0002] There are about 10 species, 3 subspecies and 2 varieties of Patrinia plants in the family Patrinaceae, including 9 species and 2 subspecies recorded for medicinal purposes. Its plant resources are very rich and are distributed all over the country. This genus of plants has a long history of medicinal use in my country. The Paijiang (also known as deer intestine) recorded in "Shen Nong's Materia Medica" is the Huanghuabaijiang P. scabiosafo2lia and Baihuabaijiang Psinensis that are currently used. In recent years, research results at home and abroad have continuously confirmed that plants of this genus and their extracts have extensive and efficient physiological activities such as anticancer, antibacterial, and s...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61P35/00A61K125/00A61J3/06A61K36/185A61P31/12A61K9/20A61P31/04A61K47/44A61K47/10A61K47/36
Inventor 曲韵智
Owner 云南云河药业股份有限公司
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