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Medicinal composition for delaying male senility

A composition and aging technology, applied in the field of medical preparations of plant materials, can solve problems such as inconvenience of life of patients, and achieve the effects of enhancing anti-fatigue ability, delaying male aging, and increasing serum testosterone

Inactive Publication Date: 2010-05-26
广州淡韵生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, testosterone replacement therapy still has shortcomings. There are a variety of androgen target cells in the human body. For example, long-term use of testosterone replacement therapy may cause prostatic tissue hyperplasia in some people. bring inconvenience

Method used

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  • Medicinal composition for delaying male senility
  • Medicinal composition for delaying male senility
  • Medicinal composition for delaying male senility

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0066] 1. Preparation of each component in the active ingredient:

[0067] (1) Epimedium extract: Weigh the dry powder of the whole herb of Epimedium, add 10 times the amount of distilled water, heat to a slight boil for 30 minutes, cool, and coarsely filter: repeat the extraction of the filter residue once; combine the coarse filtrate twice, and suction filter . Adopt AB-8 macroporous adsorption resin, adopt 70% ethanol as eluent during elution, the amount of eluent is 6 times of amount resin volume, elution, the solution after resin elution is successively extracted 3 times with chloroform ( Remove the less polar impurities) and extract with ethyl acetate 3 times, each time the amount of extractant is 2 times of the volume of the liquid to be extracted, combine the ethyl acetate phases, and concentrate to obtain a yellow powder. The above yellow powder is recrystallized with 60% ethanol to obtain a light yellow extract containing 90% total flavonoids of Epimedium.

[0068]...

example 2

[0076] 1. Preparation of each component in the active ingredient:

[0077] (1) Epimedium extract: Weigh the dry powder of the whole herb of Epimedium, then extract it with 10 times the volume of 70% ethanol under reflux, collect the reflux liquid, filter and recover the ethanol, concentrate and dry in a thin film rotary evaporator to obtain Epimedium Huskwort extract, which contains 20% of total flavonoids of Epimedium.

[0078] (2) Chinese yam extract: crush the Chinese yam decoction pieces to about 10 meshes, add an equal volume of 2% sulfuric acid and petroleum ether according to the ratio of raw medicinal material: hydrolyzate = 1:12, hydrolyze at 90°C for 5 hours, pour out, Cool, separate layers, take the upper layer (petroleum ether part), wash with sodium carbonate solution until neutral, then wash with distilled water, recover petroleum ether, evaporate to dryness, then wash with ethanol, recover ethanol, evaporate to dryness, and vacuum dry at 70°C , get yam extract,...

example 3

[0086] 1. Preparation of each component in the active ingredient:

[0087] (1) Epimedium extract: Weigh the dry powder of the whole herb of Epimedium, add 10 times the amount of distilled water, heat to a slight boil for extraction for 30 minutes, cool, and coarsely filter; repeat the extraction of the filter residue once; combine the coarse filtrate twice, and suction filter . Get the pretreated D101 macroporous adsorption resin, wet-pack the column, put the Epimedium water extract on the D101 resin column (the weight of the resin is 100g), wash the resin column with 5 times the volume of distilled water, and then use 3 times the volume of 50% Eluted with ethanol, concentrated to dryness under reduced pressure at 60°C, extract of Epimedium, which contains 70% of total flavonoids of Epimedium.

[0088] (2) Chinese yam extract: crush the yam decoction pieces to about 10 meshes, add an equal volume of 2% sulfuric acid at the ratio of raw medicinal material: hydrolyzate = 1:10, ...

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Abstract

The invention is concerned with the medication combination for staying caducity of men, which combined by the active constituent and the acceptable accessories medically. The active constituent combines with the weight proportion: barrenwort extract is 20% to 70%, yam extract is 30% to 80%; barrenwort extract contains 20% to 90% of barrenwort flavones; yam extract contains 20% to 60% of yam sapogenin. The invention can increase serum testosterone, reinforce anti-fatigue capability, anti-freeradical capability, etc.

Description

technical field [0001] The invention relates to a medical preparation derived from plant materials, in particular to a plant material medical preparation with the effect of delaying male aging. Background technique [0002] With the acceleration of my country's population aging process, the increase of the elderly population and the improvement of living standards, the health problems of middle-aged and elderly men have attracted more and more attention. In the process of male aging, the most prominent manifestation is the decline in the function of the reproductive axis of the hypothalamus-pituitary-testis. As the endocrine hormone of the reproductive axis, the level of testosterone gradually decreases with age. In men over 55 years old, the total serum testosterone drops by about 36%, while the free testosterone drops by about 50%. The serum dehydroepiandrosterone and its sulfides are also obvious. decline. The main reason for the decline of testosterone level is hypotha...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8945A61K9/20A61K9/48A61P39/06A61P15/08
Inventor 王剑
Owner 广州淡韵生物科技有限公司
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