Method for predicting mass spectrum mass measurement error

A quality measurement and prediction method technology, applied in measurement devices, instruments, scientific instruments, etc., can solve problems such as large differences in measurement errors, and achieve the effect of high prediction accuracy
CN101196498AInactive Publication Date: 2008-06-11INST OF COMPUTING TECH CHINESE ACAD OF SCI
1 Cites 8 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
INST OF COMPUTING TECH CHINESE ACAD OF SCI
Publication Date
2008-06-11
Estimated Expiration
Not applicable · inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The invention discloses a prediction method of the inaccuracy of measurement of the mass spectrum quality, which comprises the following steps: first, resolve the inaccuracy of measurement of the substance into the system error and the random error; second, calculate the inaccuracy of measurement of the sample point in the mass spectrum, wherein the sample point comprises the hydronium, sum of the hydronium or difference of the hydronium; third, select the maximum value and minimum value of the objective function in random error to determine the parameter value of the distillation function in system error. The inaccuracy of measurement of the sample point calculated in the mass spectrum is gained by predicting the molecular formula of the hydronium. The advantages of the invention are that: no extra internal or external standards required as the reference; no pre-identification is needed; both the error condition of individual mass spectrum and the error distribution condition of all mass spectrum of the whole samples; high predicting accuracy.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention relates to a mass spectrometry data preprocessing method, in particular to a mass spectrometry mass measurement error prediction method based on ion molecular formula prediction. Background technique

[0002] Any measurement tool in reality has certain measurement errors. Mass spectrometers are no exception. The function of a mass spectrometer is to measure the mass of charged ions. In the identification of protein peptides, these measurement errors will directly affect the protein identification results. Therefore, it is very important to analyze the measurement errors of the instrument and calibrate them.

[0003] The laboratory environment, such as temperature and humidity, has a great impact on the measurement accuracy of mass spectrometry. Even if the instrument is calibrated before measuring the sample to achieve an accuracy of 5ppm, the measurement error can be as high as 100ppm or more when measuring the actual sample. Therefore...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More