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Use of Loosestrife total saponine in preparing medicine for treating liver cancer

A technology for the treatment of liver cancer and loosestrife, applied in the field of natural medicine, can solve the problems of adverse reactions and small side effects

Inactive Publication Date: 2010-06-02
SUZHOU UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Drug therapy is the most important method to treat cancer clinically, but at present, all antineoplastic drugs have serious adverse reactions. Therefore, it has always been the focus of the international medical community to find antineoplastic drugs with significant effects and less toxic side effects from traditional Chinese medicine. hot topic

Method used

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  • Use of Loosestrife total saponine in preparing medicine for treating liver cancer
  • Use of Loosestrife total saponine in preparing medicine for treating liver cancer
  • Use of Loosestrife total saponine in preparing medicine for treating liver cancer

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Embodiment 1

[0070] Get 600g of pearl vegetable, pulverize it, use 12, 10, and 8 times the amount of 80% ethanol to reflux extract three times, each time for 1.5 hours, combine the filtrate, recover the ethanol under reduced pressure to obtain the extract, add water to dissolve the extract, filter, and concentrate the filtrate to 0.9ml / g crude drug. The concentrated solution was adjusted to pH 5.0 with dilute hydrochloric acid, then adsorbed by AB-8 macroporous adsorption resin at a flow rate of 1.0ml / min, washed with water until the eluate was nearly colorless, then eluted with 40% ethanol, and collected the eluate , after removing ethanol by evaporation, add n-butanol to extract 3 times, 100ml each time, combine the extracts, add n-butanol saturated water to wash 3 times, each time 10ml, recover n-butanol under reduced pressure until it is odorless, extract 80°C Vacuum drying for 2 hours yielded 2.1 g of loosestrife extract with a total saponin content of about 55%.

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Abstract

The invention relates to the field of natural medicine, in particular to an application of total saponins of loosestrife. The invention is characterized in that the total saponins of loosestrife can be used to prepare drugs for treating tumors, and particularly has good anti-hepatoma effect.

Description

technical field [0001] The invention relates to the field of natural medicines, in particular to an anti-tumor application of total saponins from nacelle. Background technique [0002] Malignant tumors are the second killer of human beings next to cardiovascular diseases. With the progress of industrialization and the increase of the proportion of the elderly population, the incidence of tumors has shown a significant upward trend in the past 20 years. Drug therapy is the most important method to treat cancer clinically, but at present, all antineoplastic drugs have serious adverse reactions. Therefore, it has always been the focus of the international medical community to find antineoplastic drugs with significant effects and less toxic side effects from traditional Chinese medicine. hot topics. [0003] Lysimachia clethroide Duby, English name: Lysimachia clethroide Duby, is the root or whole plant of Primulaceae Sansevieria clethroide. It tastes bitter, pungent, and mild...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61P35/00A61P1/16A61K36/185
Inventor 唐丽华游本刚黄荣华潘海敏李新章
Owner SUZHOU UNIV
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