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Magnolia flower volatile oil spray for nose

A technology of volatile oil and oily nose, which is applied in the field of magnolia unilateral nasal spray, which can solve the problems of slow onset of action, long time to reach the diseased part, and increased burden of body excretion.

Inactive Publication Date: 2008-12-03
JILIN HUINAN TIANTAI PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0018] The invention provides a magnolia volatile oil nasal spray to solve the problems of slow onset of current oral medicines, long time to reach the diseased part, and increased burden on body excretion

Method used

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  • Magnolia flower volatile oil spray for nose
  • Magnolia flower volatile oil spray for nose
  • Magnolia flower volatile oil spray for nose

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0255] It is made from raw materials and excipients in the following proportions by volume:

[0256] Magnolia volatile oil 40ml, polysorbate 80 40ml,

[0257] Glycerin 20ml.

[0258] The preparation method of the present invention is:

[0259] Take the polysorbate 80 and glycerin in the formula, add 100ml of absolute ethanol, stir to dissolve it, slowly add magnolia volatile oil under stirring at a speed of 900r / min, stir for 10 minutes at a speed of 900r / min, and then Add distilled water to constant volume to 1000ml, filter through a 0.22μm microporous membrane, and pack in aliquots.

Embodiment 2

[0261] Magnolia volatile oil 50ml, polysorbate 80 50ml, glycerin 26ml.

[0262] The preparation method of the present invention is:

[0263] Take the polysorbate 80 and glycerin in the formula, add 300ml of absolute ethanol, stir to dissolve it, under stirring at a speed of 1000r / min, slowly add magnolia volatile oil, stir for 10 minutes at a speed of 1000r / min, and then Add distilled water to constant volume to 1000ml, filter through a 0.22μm microporous membrane, and pack in aliquots.

Embodiment 3

[0265] Magnolia volatile oil 60ml, polysorbate 80 60ml,

[0266] Glycerin 32ml.

[0267] The preparation method of the present invention is:

[0268] Take the polysorbate 80 and glycerin in the formula, add 500ml of absolute ethanol, stir to dissolve it, and slowly add magnolia volatile oil under stirring at a speed of 1100r / min, stir for 10 minutes at a speed of 1100r / min, and then Add distilled water to constant volume to 1000ml, filter through a 0.22μm microporous membrane, and pack in aliquots.

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Abstract

The invention relates to a Flos Magnoliae volatile oil nasal spray, belonging to the Chinese traditional medicine preparation field. The nasal spray is prepared by the following raw material medicines and auxiliary materials in volume portion: 40 to 60ml of Flos Magnoliae volatile oil, 40 to 60ml of polysorbate 80 and 20 to 32ml of glycerin. The preparation method comprises the following steps that: the polysorbate 80 and the glycerin in the formula are taken and added with 100 to 500ml of absolute ethyl alcohol and stirred so as to dissolve the polysorbate 80 and the glycerin in the absolute ethyl alcohol; under the stirring at a rotary speed of between 900 and 1,100r / min, the mixed solution is slowly added with the Flos Magnoliae volatile oil and stirred for 10 minutes at a rotary speed of between 900 and 1,100r / min; and the mixed solution is added with distilled water until the constant volume is 1,000ml, and is filtered through a micro-hole filter membrane with a hole diameter of 0.22mu m. The nasal spray of the invention has the effects of dispelling chill, removing nasal obstruction and resisting allergy; moreover, the nasal spray is used to treat acute and chronic rhinitis, allergic rhinitis, sinusitis, nasal obstruction, nasosinusitis and nasal discharge. The nasal spray is used to spray four times once, twice a day.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine preparations, and relates to a nasal spray of magnolia unilateral preparation for treating acute and chronic rhinitis. Background technique [0002] Rhinitis is a common multiple respiratory disease. Its incidence has no obvious regional, seasonal, age, and gender differences, so rhinitis can be suffered from all year round, all over the country, men, women, and children. Its incidence rate accounts for about 5-6% of the total population. And allergic rhinitis is the most common, accounting for about 30% of various nasal diseases. The main causes of the disease are bacteria, virus attack, pollen-like substance allergy, cold air allergy, environmental pollution, physical and chemical factors. The clinical manifestations are nasal congestion, runny nose, shortness of breath, sore nose and eyes, hypoxia and other symptoms. If it is not treated in time, it will recur, and hypoxia can ca...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/575A61K9/72A61K47/34G01N30/02G01N30/90A61P11/02A61K47/10A61K47/26
Inventor 王晓华付雅彬邢哲勋宋明武李敏刘建恒
Owner JILIN HUINAN TIANTAI PHARMA
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