Methods of preventing or treating sinusitis with oxidative reductive potential water solution

Abstract

Provided is a method for preventing or treating sinusitis by administering a therapeutically effective amount of an oxidative reduction potential (ORP) water solution that is stable for at least about twenty-four hours. The ORP water solution administered in accordance with the invention can be combined with one or more suitable carriers. The ORP water solution can be administered alone or, e.g., in combination with one or more additional therapeutic agents.

Description

CROSS-REFERENCE TO RELATED APPLICATIONS [0001] This patent application claims the benefit of U.S. Provisional Patent Application Nos. 60 / 760,635 filed Jan. 20, 2006; 60 / 760,567 filed Jan. 20, 2006; 60 / 760,645 filed Jan. 20, 2006; and 60 / 760,557 filed Jan. 20, 2006; all of which are hereby incorporated by reference in their entireties.BACKGROUND OF THE INVENTION [0002] The cranial sinuses are air chambers within the bone of the cheeks, eyebrows and jaw. These chambers include the frontal sinuses in the eyebrow area, maxillary sinuses inside each cheekbone, ethmoid sinuses just behind the bridge of the nose and between the eyes, and sphenoid sinuses located behind the ethmoids in the upper region of the nose and behind the eyes. The sinuses are lined by a respiratory type epithelium with an underlining subepithelial layer rich in mucus glands and small blood vessels. [0003] Sinusitis is a condition in which the lining of the sinuses becomes inflamed. Sinusitis can be acute or chronic....

AI Technical Summary

Benefits of technology

[0011] The method of the present invention can be effective for treating or preventing acute sinusitis and chronic sinusitis, and can be effective for treating or preventing sinusitis that results from, e.g., an allergic reaction, asthma, or inflammation affecting one or more tissues in the one or more of the cranial sinuses or in the upper respiratory airway. The method of the present invention also can be effective for treating or preventing sinusitis that results from an infection, e.g., by one or more microorganisms, which can include viruses, bacteria, and fungi, which are preferably susceptible to the ORP water solution. Susceptible viruses can include, e.g., coxsackie viruses, adenoviruses, rhinoviruses and influenza viruses. Susceptible bacteria can include, e.g., Streptococcus pneumoniae, Haemophilus influenzae, staphylococci, non-pneumococcal streptococci, corynebacterium, and anaerobes. Susceptible fungi can include, e.g., zygomycetes, aspergillus, and candida.

Problems solved by technology

This inflammation results in increased mucus production and congestion of the nasal passages.

This congestion predisposes the individual to bacterial sinusitis.

Although fungi are abundant in the environment, they usually are harmless to healthy people.

However, fungi, such as Aspergillus, can cause serious illness in people whose immune systems are hypersensitive to Aspergillus.

Each of these drugs has side effects and other drawbacks.

For example, nonsteroidal anti-inflammatory agents can produce adverse gastronintestinal and cardiovasular side effects.

When drug therapy fails, surgery is the only alterative to treat sinusitis but, surgery can result in significant morbidity, pain, and can prolong recovery.

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