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Children's granules for clearing heat and suppressing cough and preparation method thereof

A kind of granule and pediatric technology, applied in the direction of pharmaceutical formula, medical preparations containing active ingredients, plant raw materials, etc., can solve the problems of limited curative effect, prone to drug resistance, difficult to take effect of antibiotics, etc.

Active Publication Date: 2011-08-24
浙江泰利森药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, most upper respiratory tract infections in children are viral infections. Antibiotics are often difficult to be effective, and drug resistance is easy to develop. Other chemical drugs can only be treated symptomatically. Some Chinese patent medicines have a slow onset time due to their composition and dosage. , with limited efficacy

Method used

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  • Children's granules for clearing heat and suppressing cough and preparation method thereof
  • Children's granules for clearing heat and suppressing cough and preparation method thereof
  • Children's granules for clearing heat and suppressing cough and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment approach 1

[0012] 1. Production process research

[0013] 1.1 Prescription: Ephedra 150g, Bitter almond (fried) 200g, Gypsum 450g, Licorice 150g, Scutellaria baicalensis 300g, Radix Radix 300g, Bean root 150g.

[0014] 1.2 Extraction: Take ephedra and gypsum coarse powder, add 8 times the amount of water, heat and boil for 30 minutes. Add licorice, scutellaria baicalensis, isatis root, bitter almond (stir-fried), bean root and other five traditional Chinese medicines, add water 4 times the amount of crude medicine (referring to the total amount of all Chinese medicines), and boil for 2 hours. The decoction is discharged through a pipeline filter. Adding water for the second time is 3 times the amount of crude drug (referring to the total whole Chinese medicine amount), and boiled for 1 hour. The decoction is released through the pipeline filter. Combine the two decoctions, concentrate under reduced pressure to about 1 / 3 of the decoction, release, and let stand overnight. Aspirate the...

Embodiment approach 2

[0137] 1. Prescription

[0138] Ephedra 1.8kg Bitter almond (fried) 2.4kg Gypsum 5.4kg Licorice 1.8kg

[0139] Scutellaria baicalensis 3.6kg Radix isatidis 3.6kg Bean root 1.8kg Sucrose 5.832kg

[0140] Citric acid 0.096kg Sodium cyclamate 0.096kg Dextrin Appropriate amount

[0141] Made into 12.0kg (6g×2000 bags) Qingrezhike granules for children

[0142] 2. Preparation method

[0143] Take ephedra and gypsum coarse powder, add 8 times the amount of drinking water (58L), heat and boil for 30 minutes. Add licorice, scutellaria baicalensis, Radix Isatidis, bitter almond (stir-fried), bean root and other five flavors of Chinese medicine, add drinking water to 4 times the amount of crude medicine (82L), boil for 2 hours. The decoction is discharged through a pipeline filter. Add water for the second time, which is 3 times the amount of crude drug (61L), and boil for 1 hour. The decoction is released through the pipeline filter. Combine the two decoctions, concentrate under...

Embodiment approach 3

[0147] Take 180g of ephedra, 430g of gypsum, add water and boil for half an hour, then add 220g of bitter almonds (fried), 130g of licorice, 320g of skullcap, 280g of isatidis root and 160g of bean root, add water and boil twice, the first time for 2 hours, the second time For 1 hour, combine the decoctions, filter, and concentrate the filtrate under reduced pressure to a thick paste with a relative density of 1.35-1.38 (60° C.), add 9 g of sodium cyclamate, 7 g of citric acid, 470 g of sucrose, and mix in an appropriate amount of dextrin. Make 1000g of granules and dry (80°C) to get it. (Concrete process is identical with embodiment one)

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Abstract

The invention discloses a heat clearing and cough relieving granule for children and a preparation method thereof; the heat clearing and cough relieving granule for children is prepared by the raw materials of Chinese ephedra, (fried) bitter almond, gypsum, liquorice, radix scutellariae, radix isatidis and rhizoma menispermi; the weight of each raw material required for preparing 1000g of the heat clearing and couch relieving granule for children is as follows: 100-200g of Chinese ephedra, 180-220g of (fried) bitter almond, 400-500g of gypsum, 180-220g of liquorice, 270-330g of radix scutellariae, 280-320g of radix isatidis and 130-180g of rhizoma menispermi. The granule of the invention has remarkable functions of clearing heat, ventilating the lung and relieving asthma as well as definite and good curative effects on the symptoms caused by exogenous infection of children such as fever with chilliness, cough with yellow sputum, tachypnea, hyperpnea, dry mouth, raucity, swollen sore throat, tonsillitis, and the like; furthermore, the granule of the invention has good taste, does not contain any preservatives and is especially suitable for children.

Description

technical field [0001] The invention relates to Xiaoer Qingrezhike granule and a preparation method thereof, belonging to the technical field of traditional Chinese medicine. Background technique [0002] Upper respiratory tract infection is the most common disease in children. It is often caused by exogenous pathogenic factors, such as fever, cough with yellow sputum, wheezing, and sore throat. At present, chemical drugs such as antibiotics, antipyretic and analgesics, antitussive and expectorant drugs, and Chinese patent medicines such as Pediatric Kechuanling Oral Liquid and Pediatric Feire Kechuan Oral Liquid are often used clinically. However, most upper respiratory tract infections in children are viral infections. Antibiotics are often difficult to be effective, and drug resistance is easy to develop. Other chemical drugs can only be treated symptomatically. Some Chinese patent medicines have a slow onset time due to their composition and dosage. , with limited effic...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61P11/14A61K47/40A61K36/736A61K33/06A61K9/16
Inventor 肖亚宝崔生法文君叶小女
Owner 浙江泰利森药业有限公司
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