Homogeneous crosslinking beta-cyclodextrin/wolfram carbine composite microsphere and method of producing the same

Abstract

The invention discloses an isotropic crosslinking beta-cyclodextrin / tungsten carbide composite microsphere and a preparation method thereof. The preparation method comprises the following steps: firstly, beta-cyclodextrin is dissolved into a sodium hydroxide aqueous solution, and the mixture is dripped with epichlorohydrin and undergoes stirring reaction under heating condition, so as to generateviscose; secondly, the viscose is added with tungsten carbide powder, oil dispersed phase and a dispersant under the condition of mechanical stirring to form a reversed phase suspension dispersion system; thirdly, the epichlorohydrin is added into the reversed phase suspension dispersion system, and the composite microsphere is obtained after mechanical stirring reaction; and fourthly, after the reversed phase suspension dispersion system is cooled, the composite microsphere is filtered, cleaned and neutralized, and subjected to wet sieving and expanded bed floatation. The composite microsphere developed by the method has the advantages of good hydrophilicity and sphericity, stable properties, low cost, high density, easy adjustment and so on, and can be used as a substrate during the process of expanded bed absorption as shown by an expanding performance test experiment.

Description

technical field

[0001] The invention relates to the synthesis of functional materials, in particular to a homogeneous crosslinked β-cyclodextrin / tungsten carbide composite microsphere and a preparation method thereof. Background technique

[0002] Expanded bed adsorption (EBA) technology is a new type of biochemical separation technology, which integrates solid-liquid separation, concentration and initial purification, and can directly capture the target product from the feed liquid containing solid particles. Expanded bed is a special case of fluidized bed, which uses the physical properties of the adsorbent itself, combined with a special fluid distribution device, to obtain a stable fluidized bed with a small degree of back mixing, thus overcoming the inability of traditional fixed beds to deal with At the same time, because the adsorbent particles are stably graded in the expanded bed, the feed liquid passes through the bed in a form close to the plug flow, and the degre...

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