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Traditional Chinese medicine composition for treating male infertility, preparation method and quality control method thereof

A quality control method and technology for male infertility, applied in the field of traditional Chinese medicine composition for treating male infertility and its preparation, traditional Chinese medicine composition and its preparation method, and quality control, which can solve problems such as uncertain curative effect

Active Publication Date: 2009-04-29
BEIJING ASIA EAST BIO PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the therapeutic methods that have a certain clinical effect include endocrine therapy, treatment of reproductive tract inflammation, immunotherapy, surgical treatment, and artificial insemination. There are still many male infertility with unknown causes and unclear diagnoses. The treatment methods for this situation are summarized There are: hormones, antibiotics, thyroxine, vitamins, trace elements, amino acids and other drugs, supplemented by advising patients to avoid alcohol and tobacco, preventing mental stress, excessive fatigue, and maintaining normal nutrition and regular living habits, etc., but the curative effect is not sure

Method used

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  • Traditional Chinese medicine composition for treating male infertility, preparation method and quality control method thereof
  • Traditional Chinese medicine composition for treating male infertility, preparation method and quality control method thereof
  • Traditional Chinese medicine composition for treating male infertility, preparation method and quality control method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0178] Goji berry 56g Shayuanzi 25g Raspberry 20g

[0179] Schisandra 5g Plantain (stir-fried with salt) 7g

[0180] Weigh the above raw materials and the above five flavors, use ultra-fine pulverization technology, pulverize into fine powder, and mix well; when 90-110g of honey is at 116-118°C, the refining density is 1.37, that is, refined honey is obtained; add refined honey for every 100g of powder 40g and 110g of water, pan pellets, dried at 60°C for 11 hours, made into 100g, ready to be obtained.

[0181] (1) Take 5g of this product, grind it finely, add 50ml of diethyl ether, treat it with ultrasound for 20 minutes, filter, evaporate the filtrate to dryness, add 1ml of ethyl acetate to dissolve the residue, and use it as the test solution. Take another 1 g of wolfberry reference medicinal material, grind it, add 20 ml of ether, and prepare the reference medicinal material solution in the same way. According to the thin-layer chromatography ("Chinese Pharmacopoeia" 200...

Embodiment 2

[0190] Goji berry 56g Cuscuta (fried) 25g Raspberry 20g

[0191] Schisandra (steamed) 5g Plantain (salt fried) 7g

[0192] Weigh the above raw materials and the above five flavors, use ultra-fine pulverization technology, pulverize into fine powder, and mix well; when 90-110g of honey is at 116-118°C, the refining density is 1.37, that is, refined honey is obtained; add refined honey for every 100g of powder 40g and 110g of water, pan pellets, dried at 60°C for 11 hours, made into 100g, ready to be obtained.

[0193] (1) Take 5g of this product, grind it finely, add 50ml of diethyl ether, treat it with ultrasound for 20 minutes, filter, evaporate the filtrate to dryness, add 1ml of ethyl acetate to dissolve the residue, and use it as the test solution. Take another 1 g of wolfberry reference medicinal material, grind it, add 20 ml of ether, and prepare the reference medicinal material solution in the same way. According to the thin-layer chromatography ("Chinese Pharmacopoeia"...

Embodiment 3

[0203] Goji berry 15g Cuscuta (stir-fried) 20g Raspberry 10g

[0204] Schisandra 1g Plantain (stir-fried with salt) 4g

[0205] Weigh the above raw materials and the above five flavors, use ultra-fine pulverization technology, pulverize into fine powder, and mix well; when 90-110g of honey is at 116-118°C, the refining density is 1.37, that is, refined honey is obtained; add refined honey for every 100g of powder 40g and 110g of water, pan pellets, and dried at 60°C for 11 hours to obtain.

[0206] (1) Take 5g of this product, grind it finely, add 50ml of diethyl ether, treat it with ultrasound for 20 minutes, filter, evaporate the filtrate to dryness, add 1ml of ethyl acetate to dissolve the residue, and use it as the test solution. Take another 1 g of wolfberry reference medicinal material, grind it, add 20 ml of ether, and prepare the reference medicinal material solution in the same way. According to the thin-layer chromatography ("Chinese Pharmacopoeia" 2005 edition app...

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Abstract

The invention relates to a traditional Chinese medicine composition used for treating male sterility, a preparation method and a quality control method thereof. The traditional medicine composition contains crude drugs such as fruits of Chinese wolfberry, dodder (fried), raspberry, fructus schizandrae (steamed), plantago seeds (fried with salt) and the like. The preparation method comprises an ultrafine grinding technology and the like. The quality control method of the medicine composition comprises a thin-layer identification method for fruits of Chinese wolfberry, dodder, raspberry, fructus schizandrae and plantago seeds as well as a method for measuring the content of schizandrin B in the plantago seeds. The medicine composition has obvious therapeutic effect in treating renal deficiency and lumbago, post-micturition dribble, spermatorrhea, premature ejaculation, impotence and sterility.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, a preparation method and a quality control method thereof, in particular to a traditional Chinese medicine composition for treating male infertility, a preparation method and a quality control method thereof, and belongs to the technical field of traditional Chinese medicine. Background technique [0002] Male infertility is not a single specific disease, but male genitalia caused by multiple causes, including abnormalities of different levels of internal and external genitalia and gonad axis, and finally manifested as a syndrome of decreased or lost fertility. Because of this, it is impossible for male infertility to cure male infertility caused by various causes with a specific drug or method. At present, the therapeutic methods that have a certain clinical effect include endocrine therapy, treatment of reproductive tract inflammation, immunotherapy, surgical treatment, and artifici...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/815A61K9/20A61K9/48A61P15/08G01N30/02G01N30/90
Inventor 付立家付建家
Owner BEIJING ASIA EAST BIO PHARMA CO LTD
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