Synergistic microbicidal compositions
A composition and mixture technology, which is applied in biocides, chemicals for biological control, animal repellants, etc., can solve the problems of inability to provide microbial control, poor microbial activity, etc.
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[0055] Materials and methods
[0056] The synergy of the combinations of the invention is demonstrated by testing a wide range of compound concentrations and ratios.
[0057] A measure of synergy is Kull, F.C.; Eisman, P.C.; Sylwestrowicz, H.D. and Mayer, R.L. in Applied Microbiology (Applied Microbiology) 9: 538-541 (1961) proposed in the industry acceptable method, the method uses The ratio determined by:
[0058] Q a / Q A +Q b / Q B = Synergy Index ("SI")
[0059] In the formula:
[0060] Q A = Concentration of Compound A (first component) that produced the endpoint when used alone (MIC of Compound A), in ppm.
[0061] Q a = Concentration of compound A in ppm which produces the endpoint when used in mixture.
[0062] Q B= Concentration of Compound B (second component) that produced the endpoint when used alone (MIC of Compound B) in ppm.
[0063] Q b = Concentration of compound B in ppm which produces the endpoint when used in mixture.
[0064] When Q a / Q ...
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