Susceptible/resistant MUC13 molecular marker capable of identifying F4 weaning brash of piglets and application

Abstract

The invention discloses a susceptible / resistant MUC 13 molecular marker capable of identifying F4 weaning brash of piglets of western pig breeds and application thereof to genetic improvement of pig breeds. The molecular marker firstly identifies single nucleotide polymorphism (SNP) A157G, and then adopts a SNaPshot method to perform genotype judgment on the SNPA157G. The invention detects a polymorphic site through modern molecular biology technology, utilizes the marker assisted selection (MAS) to select advantageous allelotype reserved individual breed, can obviously improve weaning brash resistance of species groups, and greatly reduces the death rate of the piglets.

Description

MUC13 Molecular Marker and Its Application to Differentiate Susceptibility / Resistance to Weaned Piglet F4 Diarrhea technical field The invention relates to the field of animal molecular biology technology and breeding, in particular to a MUC13 molecular marker capable of identifying the susceptibility / resistance to weaned piglet F4 diarrhea and its application. Background technique Infectious diseases of livestock and poultry cause huge economic losses to livestock and poultry production all over the world every year. The losses caused by this account for 17% (1.7 billion pounds) of the annual trade volume in developed countries, and as high as 35%-50% in developing countries. Piglet diarrhea is the most common and very important disease. The mortality rate of piglets caused by diarrhea is 11.5%-29.5%. Among them, the morbidity and mortality caused by E. coli account for 56.2% of the incidence and mortality of pig diarrhea and 24.7%. Escherichia coli disease seriously aff...

AI Technical Summary

Problems solved by technology

Escherichia coli disease seriously affects the growth and development of piglets, leading to increased feeding costs and huge economic losses to the pig industry. Vaccination or antibacterial drugs are used to prevent and treat the disease. On the one hand, long-term use is likely to cause drug resistance. The abuse of drugs will lead to drug residues in animal products and become drugs and food, which will eventually affect human health

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