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Enhanced sample processing devices, systems and methods

A sample processing and processing chamber technology, applied in the field of amplifying genetic material, can solve the problems of limited and widely used disks, and achieve the effect of improving uniformity

Active Publication Date: 2013-05-01
索灵意大利股份公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Additionally, the technical nature of these processes requires highly skilled personnel to obtain accurate results
[0014] The use of magnetic disk devices to integrate multiple thermal processing steps into a single device suffers from a number of disadvantages, including the use of costly silicon substrates, and the incorporation of costly heating and / or cooling systems built into the magnetic disks
Therefore, the cost of the disk can limit its widespread use

Method used

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  • Enhanced sample processing devices, systems and methods
  • Enhanced sample processing devices, systems and methods
  • Enhanced sample processing devices, systems and methods

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Embodiment Construction

[0096] The present invention provides for use in processes involving heat treatment (such as PCR amplification, ligase chain reaction (LCR), autonomous sequence replication, enzyme kinetic studies, cognate ligand binding assays) that require precise thermal control and / or rapid thermal changes. Sensitive chemical processes of the class, as well as more complex biochemical or other processes). The device may include, for example, reflective layers, baffle structures, valve structures, trapping plugs, thermal indicators, absorbent materials, and other materials that facilitate rapid and accurate thermal processing of sample material in the processing chamber of the device or part.

[0097] Although the construction of several exemplary embodiments of the device are described below, a rotatable sample processing device according to the principles of the present invention can be fabricated according to the principles described in: Filed June 28, 2000, entitled THERMAL PROCESSING D...

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Abstract

Devices, systems, and methods for processing sample materials. The sample materials may be located in a plurality of process chambers in the device, which is rotated during heating of the sample materials.

Description

[0001] Cross references to related patent applications [0002] This patent application is filed under 35 U.S.C. § 119(e) to U.S. Provisional Patent Application No. 60 / 871,620, which patent application is hereby incorporated by reference in its entirety. technical field [0003] The present invention relates to devices, methods and systems for processing sample material, such as methods for amplifying genetic material and the like. Background technique [0004] Many different chemical, biochemical, and other reactions are sensitive to temperature changes. Examples of thermal processing in the field of gene amplification include, but are not limited to, polymerase chain reaction (PCR), Sanger sequencing, and the like. Depending on the temperature of the materials involved, the reaction is either enhanced or inhibited. While it is possible to process samples individually and obtain accurate sample-to-sample results, individual processing can be time consuming and expensiv...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): B01L3/00B01L99/00
CPCB01L2400/0409B01F11/0074B01F15/0233B01L2200/0684B01L2200/0668B01L2300/0806B01L3/502738B01L2400/0677B01L3/50273B01F13/0059Y10T137/7758Y10T137/0753Y10T137/0329B01F31/651B01F33/30B01F35/71725G01N1/44G01N35/00B01L3/00
Inventor 威廉姆·拜丁汉姆克里斯托弗·R·科考伊瑟尔彼得·D·陆德外斯巴里·W·罗博莱
Owner 索灵意大利股份公司