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Medicine for preventing and treating flurouracil phlebitis

A technology of fluorouracil and phlebitis, which is applied in the field of drugs for the prevention and treatment of fluorouracil phlebitis, and can solve problems such as phlebitis

Inactive Publication Date: 2011-03-23
山西省肿瘤医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The present invention provides a drug for preventing and treating fluorouracil phlebitis in order to solve the problem in the prior art that the use of fluorouracil in chemotherapy is particularly likely to cause phlebitis

Method used

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  • Medicine for preventing and treating flurouracil phlebitis
  • Medicine for preventing and treating flurouracil phlebitis
  • Medicine for preventing and treating flurouracil phlebitis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0058] Embodiment 1, a kind of medicine of preventing and treating fluorouracil phlebitis, comprises the raw material mixing and mixing composition of following weight ratio, fresh potato juice 18 grams, 6 milligrams of dexamethasone, glucose 4 grams, 1.3 grams of paraben ethyl ester , 6 grams of glycerol.

Embodiment 2

[0059] Embodiment 2, a kind of medicine of preventing and treating fluorouracil phlebitis, comprises the raw material of following weight proportion and mixes thoroughly composition, fresh potato juice 22 grams, dexamethasone 4 milligrams, glucose 6 grams, 0.7 grams of paraben ethyl ester , 10 grams of glycerol.

Embodiment 3

[0060] Embodiment 3, a kind of medicine of preventing and treating fluorouracil phlebitis, comprises the raw material of following weight ratio and mixes thoroughly to form, fresh potato juice 20 grams, 5 milligrams of dexamethasone, glucose 5 grams, 1 gram of paraben ethyl ester , 8 grams of glycerol.

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PUM

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Abstract

The invention relates to a medicine, in particular to a medicine for preventing and treating flurouracil phlebitis, which solves the problem existing in the prior art that the use of flurouracil has great possibility to result in phlebitis during chemotherapy. The medicine is prepared by evenly mixing and blending the following weight ratio of raw materials: 18 to 22 parts of fresh potato juice, 4to 6 parts of dexamethasone, 4 to 6 parts of glucose, 0.7 to 1.3 parts of ethylparaban, and 6 to 10 parts of glycerol. The animal experiments and clinical use prove that the medicine has the effectsof preventing and treating flurouracil phlebitis.

Description

technical field [0001] The invention relates to a medicine, in particular to a medicine for preventing and treating fluorouracil phlebitis. Background technique [0002] With the development of medicine, chemotherapy of antineoplastic drugs has become one of the three major treatment methods for malignant tumors besides surgery and radiotherapy. The drug fluorouracil used in chemotherapy has a certain effect on various malignant tumors, such as: digestive tract tumors, breast cancer, ovarian cancer, choriocarcinoma, cervical cancer, liver cancer, bladder cancer, and skin cancer. It is widely used clinically. Most of the chemotherapeutic drugs used in clinic have stimulating effect on local tissues, and some highly irritating chemotherapeutic drugs are likely to cause tissue necrosis and phlebitis. Many researchers at home and abroad have found that fluorouracil has the strongest inflammatory effect due to continuous administration. If preventive measures are not taken for ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/81A61P9/00A61K31/573
Inventor 王晋芬任连生杨文琴
Owner 山西省肿瘤医院