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A medicinal preparation for treating breast cancer and preparation method thereof

A pharmaceutical preparation and breast cancer technology are applied in the field of traditional Chinese medicine preparations for treating breast cancer and their preparation, which can solve problems such as inconvenience in taking, and achieve the effects of convenient taking, reducing adverse events and reducing side effects.

Inactive Publication Date: 2010-03-24
SHUGUANG HOSPITAL AFFILIATED WITH SHANGHAI UNIV OF T C M
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

This patented technology prevents or reduces cellular transformation from growing on certain types of cells called neoplasms (cancer). It also enhances an individual’s ability to fight against these diseases without causing harmful side effects like chemotherapies used during treatment.

Problems solved by technology

This patents discusses various ways to treat breast cancer through different types of medication such as radiation therapies, chemical agents like cisplatin, fluorescence imaging techniques, hormone drugs, etc., which may cause harmful side-effects on patient outcomes due to their long term use. Current approaches involve administering these substances frequently during hospital stays despite promising results from previous trials conducted over time.

Method used

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  • A medicinal preparation for treating breast cancer and preparation method thereof
  • A medicinal preparation for treating breast cancer and preparation method thereof
  • A medicinal preparation for treating breast cancer and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] 1 part of Astragalus, 1 part of Codonopsis pilosula, 1 part of Atractylodes macrocephala, 1 part of medlar, 1 part of Nansha ginseng, 1 part of fairy spleen, 1 part of dogwood,

[0020] Take half of the amount of medicine in the above formula, add 3 times the amount of water, soak for half an hour, decoct for 45 minutes, add 3 times the amount of water, decoct for 30 minutes, filter, combine the decoction liquid, concentrate under reduced pressure, and dry under reduced pressure to obtain dry extract , crushed into fine powder (over 80 mesh). The other half of the crude drug was crushed to 80 mesh, and the 60 Sterilize, irradiate at a dose of 8k, mix with extract powder, add mannitol, lactose, sucrose powder, aspartame, menthol, mix well and use 60% ethanol as a binder to make granules. The granular preparation is 10g / bag.

Embodiment 2

[0022] 3 parts of Astragalus, 2 parts of Codonopsis, 2 parts of Atractylodes macrocephala, 2 parts of Lycium barbarum, 2 parts of Nansha ginseng, 2 parts of Xianling spleen, 2 parts of Cornus officinalis, and the rest are medicinal excipients.

[0023] Take half of the amount of medicine in the above formula, add 8 times the amount of water, soak for half an hour, decoct for 45 minutes, add 8 times the amount of water, decoct for 30 minutes, filter, combine the decoction liquid, concentrate under reduced pressure, and dry under reduced pressure to obtain dry extract , crushed into fine powder (over 80 mesh). The other half of the crude drug was crushed to 80 mesh, and the 60 Sterilization, irradiation dose 8k, mix with extract powder, add mannitol, lactose, sucrose powder, aspartame, menthol, after mixing uniformly, use 70% ethanol as binding agent to make granule; According to conventional method, Add molding excipients or flavoring excipients to make tablets.

Embodiment 3

[0025] 3 parts of Astragalus, 2 parts of Codonopsis pilosula, 2 parts of Atractylodes macrocephala, 2 parts of medlar, 2 parts of Nansha ginseng, 1 part of fairy spleen, 1 part of dogwood, and the rest are medicinal excipients.

[0026] Take half of the amount of medicine in the above formula, add 8 times the amount of water, soak for half an hour, decoct for 45 minutes, add 8 times the amount of water, decoct for 30 minutes, filter, combine the decoction liquid, concentrate under reduced pressure, and dry under reduced pressure to obtain dry extract , crushed into fine powder (over 80 mesh). The other half of the crude drug was crushed to 80 mesh, and the 60 Sterilization irradiation dose 8k, mix with extract powder, add mannitol, lactose, sucrose powder, aspartame, menthol, mix well and use 70% ethanol as binder to make granules.

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Abstract

The present invention belongs to the field of traditional Chinese pharmaceutics, which relates to a traditional Chinese medicinal preparation for treating breast cancer and preparation method thereof.The present invention adopts supplementing qi, nourishing yin, regulating the thoroughfare and controlling vessels as therapeutic principle, which adopts the extracts of the following traditional Chinese medicine raw materials: radix astragali, Radix Codonopsis, bighead atractylodes rhizome, wolfberry, adenophora tetraphylla, epimedium sagittatum, Cornus officinalis, and auxiliary material to prepare a small preparation for treating breast cancer. By animal experiment and clinic trial, the results show that the preparation particles of the present invention can inhibit tumor growth and lung metastasis of tumor-bearing mice and enhance body antitumor enhance host anti-tumor immunity; the clinical studies showed that preparation particles of the present invention can obviously decrease sideeffects caused by a medicament for treating breast cancer and auxiliary treating endocrine, reduce adverse event, improve depression, and anxiety symptoms, and improve life quality of patient. The preparation of the present invention has the advantages of convenient administration, little dosage, no toxic side effect even long-term administration, and good evaluation.

Description

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Claims

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Application Information

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Owner SHUGUANG HOSPITAL AFFILIATED WITH SHANGHAI UNIV OF T C M
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