Chinese medicament for treating hyperlipoidemia and preparation thereof

A technology of hyperlipidemia and traditional Chinese medicine, applied in the field of pharmaceutical compositions and preparations for the treatment of hyperlipidemia, which can solve the problems of unsafe hidden dangers and limit the wide use of patients, and achieve the effect of reducing TG

Inactive Publication Date: 2010-06-16
LIAONING UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the objective existence of unsafe hidden dangers, it limits the wide use of patients to a certain extent.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028]An injection of traditional Chinese medicine for treating hyperlipidemia is prepared by adding 90g of kudzu root extract, 45g of Alisma extract, 45g of hawthorn leaf extract, 8010g of leaf temperature, and 300g of mannitol, adding water for injection to 5000ml, and making 1000 sticks.

[0029] Preparation process: Accurately weigh the raw and auxiliary materials according to the above prescription, add Pueraria root extract and hawthorn leaf extract to 1000ml of water for injection and heat to dissolve completely, add Tween 80 to 1000ml of water for injection to make an aqueous solution, add Alisma extract and heat to dissolve . Add 1000ml of water for injection to mannitol, heat and stir to dissolve completely, combine the above solutions, and add water for injection to the full amount. Add 0.1% activated carbon, heat and stir for 15 minutes, and filter through a sand filter to decarbonize. The pH of the solution was measured and adjusted to 5.5, and the solution was f...

Embodiment 2

[0031] A tablet of traditional Chinese medicine for the treatment of hyperlipidemia is to get Pueraria root extract 90g, Alisma extract 45g, hawthorn leaf extract 45g, add dextrin 30g, starch 40g, microcrystalline cellulose 40g, magnesium stearate 7g and talc powder 3g, mix uniformly and make tablets, and prepare 1000 tablets altogether.

[0032] Preparation process: Precisely weigh the raw and auxiliary materials according to the above prescription, pulverize the kudzu root extract, Alisma extract and hawthorn leaf extract and pass through an 80-mesh sieve for later use. Get 10g of starch and dissolve it in hot water to make starch slurry for subsequent use. Mix kudzu root extract, alisma extract, hawthorn leaf extract, dextrin, starch, and microcrystalline cellulose evenly, add an appropriate amount of starch slurry solution, and stir evenly to make a suitable soft material. The soft material is passed through a 20-mesh sieve to make granules. The wet granules were dried u...

Embodiment 3

[0034] A kind of granule of traditional Chinese medicine for the treatment of hyperlipidemia is to get kudzu root extract 180g, Alisma extract 90g, hawthorn leaf extract 90g, powdered sugar 600g and 2% HPMC aqueous solution in right amount, mix uniformly, make granule, altogether 1000 bags are prepared.

[0035] Preparation process: Accurately weigh the raw and auxiliary materials according to the above prescription, crush the sucrose and pass through an 80-mesh sieve for standby; pueraria root extract, Alisma extract and hawthorn leaf extract are crushed and pass through a 100-mesh sieve for standby. Mix kudzu root extract, alisma extract and hawthorn leaf extract powder and powdered sugar in equal increments, add an appropriate amount of 2% HPMC aqueous solution, and stir evenly to make a suitable soft material, which is passed through a 20-mesh sieve Granules. The wet granules are dried under reduced pressure at 60°C, and the dry granules are sieved through a 18-mesh sieve...

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PUM

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Abstract

The invention belongs to the technical field of medicine, and in particular relates to a medicinal composition for treating hyperlipoidemia, a preparation method and application thereof, and a preparation containing the medicinal composition. The medicinal composition comprises the following components in part by weight: 1,000 to 8,000 parts of kudzuvine root, 800 to 3,000 parts of oriental waterplantain rhizome and 800 to 3,000 parts of crataegus leaf, wherein preferably, the medicinal composition comprises the components in part by weight: 1,000 to 6,000 parts of the kudzuvine root, 1,500 and 2,500 parts of the oriental waterplantain rhizome and 1,500 and 2,500 parts of the crataegus leaf; and the medicinal composition comprises the optimal part by weight: 3,000 parts of the kudzuvine root, 2,000 parts of the oriental waterplantain rhizome and 2,000 parts of the crataegus leaf. Based on extract, the medicinal composition comprises 300 parts of kudzuvine root extract, 150 parts of oriental waterplantain rhizome extract and 150 parts of crataegus leaf extract. The composition can be prepared into clinically or pharmaceutically acceptable formulations, has the characteristics of synergistic action and good stability, and has the effects of reducing blood fat and blood pressure, improving blood circulation and the like. The composition has the advantages of strengthened medicinal effect, exact curative effect and adverse reaction reduction, and is mainly used for preparing the medicament for treating the hyperlipoidemia.

Description

technical field [0001] The invention relates to a traditional Chinese medicine, in particular to a pharmaceutical composition containing kudzu root, alisma and hawthorn leaves for treating hyperlipidemia and a preparation thereof. Background technique [0002] Hyperlipidemia is one of the important risk factors for arteriosclerosis and coronary heart disease. With the improvement of living standards, changes in living habits, the increase of life and work pressure, and the intake of a large number of high-nutrient substances, the incidence of hyperlipidemia is increasing year by year. According to the statistics of the World Health Organization, each year my country's cardiovascular and cerebrovascular The number of deaths from the disease is about 600,000, which is shocking. The incidence of hyperlipidemia is increasing year by year, and the harm is greater. At present, there are many lipid-lowering western medicines commonly used clinically, mainly bile acid chelate resins...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/884A61P3/06
Inventor 程岚康廷国袁子民赵琳吕佳李学涛刘玉强
Owner LIAONING UNIV OF TRADITIONAL CHINESE MEDICINE
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