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Structured occllusive dressings

A so-called wound care technology, applied in the field of adhesive bandages, can solve the problems of too soft, messy wound dressing materials blending, etc.

Inactive Publication Date: 2014-05-14
JOHNSON & JOHNSON CONSUMER COPANIES
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Petroleum jelly-based formulations of conventional ointments appear too runny and messy for blending with wound dressing materials

Method used

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  • Structured occllusive dressings
  • Structured occllusive dressings
  • Structured occllusive dressings

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0054] To a Brabender Plasticorder heated to 125°C was added 180g U.S. white petrolatum, 90g Elvax 40W (a polyvinyl acetate obtained from Dupont), 15g mineral oil and 15g Kraton G 1702 (a diembedded segment copolymers, consisting of polystyrene and ethylene propylene copolymers). The composition was mixed for 60 minutes, then the temperature was lowered to 80°C and mixing continued for an additional 30 minutes. The agent was coated onto a nonwoven substrate while continuing to warm (at 80°C) using the depletion method. Place a square approximately 3 / 4 inch long in the middle of the 3 / 4 inch by 3 inch adhesive strip. A release film with a low release surface is placed over the strip, covering the adhesive and ointment surface. The strips were subjected to a standard ethylene oxide sterilization loop (175°F for 30 minutes) in the presence of water. No ointment was observed to seep or flow from the adhesive strip, and no ointment was visible on the adhesive strip.

[0055] Se...

Embodiment 2

[0057] Using the method of Example 1, 210 grams of white petrolatum, 60 grams of Elvax 40W, 15 grams of Kraton G1702 and 15 grams of lanolin alcohol were coated onto a nonwoven substrate. Ointment exudation or flow was also not observed. The hydrophilic nature of the composition was tested by observing the slow absorption of water droplets placed onto the coating of this example.

Embodiment 3-6 and comparative Embodiment A

[0059] The following five compositions were prepared as in Example 1 and also coated on nonwoven substrates.

[0060] compound

3

4

5

6

A

Kraton G 1702

11.1

7.7

11.5

11.1

--

vaseline

74.1

76.9

77.0

74.1

83.3

Elvax 40W

14.8

15.4

11.5

11.1

12.5

Elvax 150W

--

--

--

3.7

4.2

[0061] Rheometrics RDS 7700 rheometer was used to measure the change of viscosity of the composition of Example 3 with the shear rate at 35° C., and compared with the change of viscosity of white petrolatum with the shear rate. attached figure 2 A graphical representation of the results of this assay is given. A factor of 10 viscosity increase between white petrolatum and the Example 3 composition is noted.

[0062] The temperature dependence of the viscosity of the compositions of Example 6 and Comparative Example A...

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Abstract

This invention relates to a composition containing a hydrophobic solvent, a network polymer and a flow control agent which is useful in healing wounds. The composition of this invention may be applied directly to a wound to create a structured occlusive dressing. The dressings of this invention do not migrate, but maintain their integrity at skin temperature, and encourage the creation of a moist wound environment while protecting the wound in order to accelerate healing.

Description

[0001] This application is a divisional application of the parent application with application number 96105797.1. The filing date of the parent case is March 1, 1996; the title of the invention is "structured closed dressing". technical field [0002] This application is a continuation-in-part of US Patent Application No. 08 / 397,596 filed March 2, 1995 by Schiraldi et al. (hereinafter the "Schiraldi Application"). The disclosure of the Schiraldi application is hereby incorporated by reference. [0003] The present invention relates to a structured wound dressing that stays in place and does not flow, but has an ointment-like feel. The present invention also relates to an adhesive bandage comprising the above-mentioned structured dressing. Background technique [0004] Absorbent bandages have been used as wraps in the care of wounds or other skin lesions for many years. The literature ("Epidermal Wound Healing", H.I. Maibach, D.T. Rovee, editors, Year Book Medical Publishe...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61F13/02A61L15/22A61L15/20A61L15/42A61L15/44A61F13/00A61L15/10A61L15/34A61L15/58
CPCA61L15/44A61L2300/402A61L2300/412A61L15/42A61L2300/406A61L2300/41A61F2013/0091A61L2300/404A61F13/0203A61F2013/00885A61L15/20A61L15/22
Inventor M·T·席拉迪N·孔德尔M·蒙尼A·加罗J·佩卢基
Owner JOHNSON & JOHNSON CONSUMER COPANIES