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Prediction method of concentration fluctuation of measurement target components in blood, and device therefor

A technology for measuring objects and concentrations, applied in biological testing, diagnostic recording/measurement, medical science, etc., can solve problems such as unrecorded blood sugar changes and unrecorded

Active Publication Date: 2010-10-06
SYSMEX CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in WO9600110, there is no device for measuring the area under the blood concentration-time curve.
Of course, the device described in WO9600110 does not describe at all the content of using the area under the blood concentration-time curve to investigate blood sugar fluctuations

Method used

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  • Prediction method of concentration fluctuation of measurement target components in blood, and device therefor
  • Prediction method of concentration fluctuation of measurement target components in blood, and device therefor
  • Prediction method of concentration fluctuation of measurement target components in blood, and device therefor

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Embodiment Construction

[0081] Preferred embodiments of the present invention are described below with reference to the drawings.

[0082] The area under the blood concentration-time curve (Area Under the blood concentrationtime Curve: AUC) is known as a value reflecting the total amount of components circulating in a living body within a predetermined period. Specifically, AUC refers to the area enclosed by a curve (blood concentration-time curve of biological component) drawn by a graph showing the time-lapse of the blood concentration of a predetermined component in the living body and the horizontal axis (time axis).

[0083] The blood glucose AUC refers to the area (unit: mg·h / dl) of a portion enclosed by a curve drawn by a graph representing the passage of time of the blood glucose level and the horizontal axis. Blood glucose AUC can be used as an index for judging the effects of insulin and oral agents in diabetes treatment. For example, blood glucose AUC measures the value that reflects the ...

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Abstract

The invention provides a method for predicting a concentration fluctuation of a measurement target component in the blood, comprising steps of: obtaining an initial value of the amount relating to the measurement target component in a subject; obtaining, as a first measurement value, a value of an area under the blood concentration time curve of the measurement target component during a first extraction period; obtaining, as a second measurement value, a value of an area under the blood concentration time curve of the measurement target component during a second extraction period; and predicting the concentration fluctuation of the measurement target component in the blood from the initial value, the first measurement value and the second measurement value, as well as a device for predicting a concentration fluctuation of a measurement target component in the blood.

Description

technical field [0001] The present invention relates to a method and an apparatus for obtaining the area under the blood concentration-time curve of a component to be measured in blood, and using the area under the curve of the blood concentration-time curve to estimate the concentration fluctuation of the component to be measured in blood. Background technique [0002] In grasping the pathological state of diabetes, the highest blood sugar level is used as a criterion for judgment. Therefore, it is important to investigate blood sugar fluctuations in order to obtain the highest blood sugar level and the time to reach the highest blood sugar level from the start of eating. For example, when insulin is supplied to lower blood sugar levels, it is therapeutically effective to make the peak of insulin's action on a living body coincide with the peak of blood sugar levels. Therefore, when the time at which the highest blood sugar level appears is known to some extent, insulin ca...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/48
CPCA61B5/14514A61B5/14532
Inventor 佐藤利幸冈田正规
Owner SYSMEX CORP