Sinomenine hydrochloride sustained-released injection and preparation method thereof

A technology of sinomenine hydrochloride and slow-release injections, which is applied in anti-inflammatory agents, pharmaceutical formulas, non-central analgesics, etc., and can solve the problems of large side effects and frequent use
CN101396345AInactive Publication Date: 2009-04-01HUNAN ZHENGQING PHARM GRP CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
HUNAN ZHENGQING PHARM GRP CO LTD
Publication Date
2009-04-01
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a sinomenine hydrochloride sustained release injection and a preparation method thereof. The sustained release injection comprises one of synthetic polymer nanometer sinomenine hydrochloride sustained release injection, natural polymer material microsphere sinomenine hydrochloride sustained release injection, lipid sinomenine hydrochloride sustained release injection, multivesicular liposome sinomenine hydrochloride sustained release injection and gelatin sinomenine hydrochloride sustained release injection. Various sinomenine hydrochloride sustained release injections prepared by the invention by different methods can prolong the acting time of drug, reduce drug administration times, keep stable blood concentration in vivo and reduce the toxic and side effects of the drug.
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Description

technical field

[0001] The invention relates to a new pharmaceutical dosage form of sinomenine hydrochloride, in particular to a sinomenine hydrochloride sustained-release injection and a preparation method thereof. Background technique

[0002] Sinomenine is an active ingredient extracted from the traditional Chinese medicine Qingfengteng. It is an effective Chinese medicine for treating rheumatism and rheumatoid arthritis. Its hydrochloride is often used in medicine. This variety has remarkable curative effect and good market promotion, and has now become a commonly used drug. At present, sinomenine hydrochloride is mainly used as an injection for clinical treatment. Although sinomenine hydrochloride injection has a definite curative effect, it has disadvantages such as frequent use (injection once a day) and large side effects in clinical practice. Contents of the invention

[0003] One object of the present invention is to disclose a new drug dosage form of sinomenine...

Claims

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