Artificial eardrum using silk protein and method of fabricating the same

Abstract

Provided are an artificial eardrum using silk protein and a method of fabricating the same. The artificial eardrum is fabricated in the form of a silk membrane by desalinating and drying silk protein (or silk fibroin) or a silk protein complex solution obtained after removal of sericin from a silkworm cocoon or silk fiber. Thus, regeneration of an eardrum perforated due to disease or a sudden accident is stimulated, a boundary of the regenerated eardrum is clean and biocompatibility and transparency are increased. In addition, the artificial eardrum may be fabricated using the silk protein or silk protein complex solution obtained from a silkworm cocoon alone or mixed with collagen, alginic acid, PEG or pluronic 127.

Description

[0001] Cross References to Related Applications [0002] This application claims priority and benefit from Korean Patent Application No. 2009-0040200 filed on May 8, 2009, the disclosure of which is incorporated herein by reference in its entirety. technical field [0003] The present invention relates to an artificial eardrum using silk protein and a manufacturing method thereof, and more particularly, to an artificial eardrum in the form of a silk membrane using silk protein using silk protein obtained by removing sericin from silkworm cocoons or its Composite made as a raw material for the artificial eardrum that stimulates the regeneration of the eardrum perforated by disease or sudden accident, provides a clear boundary for the regenerated eardrum and is easy to use due to high biocompatibility and transparency ; and a method of manufacture thereof. Background technique [0004] Generally speaking, silk is a fabric made from cocoons formed by spinning silkworms fed wit...

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